Adjuvant daily therapy with L-arginine 2,500 mg and tadalafil 5 mg increases efficacy and duration of benefits of low-intensity extracorporeal shock wave therapy for erectile dysfunction: A prospective, randomized, single-blinded study with 1-year follow-up
Investig Clin Urol. 2022 Jan;63(1):83-91. doi: 10.4111/icu.20210317. ABSTRACT PURPOSE: To investigate a therapeutic protocol for erectile dysfunction (ED) based on the combination of low-intensity extracorporeal...
Robust W/O/W Emulsion Stabilized by Genipin-Cross-Linked Sugar Beet Pectin-Bovine Serum Albumin Nanoparticles: Co-encapsulation of Betanin and Curcumin
J Agric Food Chem. 2021 Feb 3;69(4):1318-1328. doi: 10.1021/acs.jafc.0c05212. Epub 2021 Jan 22. ABSTRACT Betanin and curcumin hold promise as natural colorants and antioxidants for...
HPLC-ESI- MS/MS analysis of beet (Beta vulgaris) leaves and its beneficial properties in type 1 diabetic rats
Biomed Pharmacother. 2019 Dec;120:109541. doi: 10.1016/j.biopha.2019.109541. Epub 2019 Oct 17. ABSTRACT The phenolic profile of the leaves of Beta vulgaris subspecies vulgaris variety rubra was...
A quantitative case study assessment of changes to hepatic metabolism from nonlactating grazing dairy cows consuming a large proportion of their diet as fodder beet
J Dairy Sci. 2019 Sep;102(9):8559-8570. doi: 10.3168/jds.2018-16009. Epub 2019 Jul 10. ABSTRACT Because of its high yield and the ability of cows to graze it...
Beet Stalks and Leaves (Beta vulgaris L.) Protect Against High-Fat Diet-Induced Oxidative Damage in the Liver in Mice
Nutrients. 2018 Jul 5;10(7):872. doi: 10.3390/nu10070872. ABSTRACT Some flavonoids identified in beet stalks can help the antioxidant endogenous defenses during a chronic inflammation process. The...
Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: a randomized crossover pilot study
J Hum Hypertens. 2016 Oct;30(10):627-32. doi: 10.1038/jhh.2016.34. Epub 2016 Jun 9. ABSTRACT Hypertension is a major risk factor for cardiovascular disease and has a prevalence...
Long-term high-dose L-arginine supplementation in patients with vasculogenic erectile dysfunction: a multicentre, double-blind, randomized, placebo-controlled clinical trial
J Endocrinol Invest. 2022 Jan 1. doi: 10.1007/s40618-021-01704-3. Online ahead of print. ABSTRACT PURPOSE: The current randomized, double-blind, placebo-controlled clinical trial addressed the effects on...
Ball milling and hot-melt extrusion of indomethacin-L-arginine-vinylpyrrolidone-vinyl acetate copolymer: Solid-state properties and dissolution performance
Int J Pharm. 2021 Dec 27:121424. doi: 10.1016/j.ijpharm.2021.121424. Online ahead of print. ABSTRACT Commonly applied approaches to enhance the dissolution properties of low water-soluble crystalline...
The Effect of L-arginine Supplementation On Blood Pressure in Adults: A Systematic Review and Dose-response Meta-analysis of Randomized Clinical Trials
Adv Nutr. 2021 Dec 30:nmab155. doi: 10.1093/advances/nmab155. Online ahead of print. ABSTRACT A decade-old meta-analytic work indicated that L-arginine supplementation might have a blood pressure...
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials
J Int Soc Sports Nutr. 2021 Dec 29;18(1):76. doi: 10.1186/s12970-021-00472-y. ABSTRACT BACKGROUND: Increasing nitric oxide bioavailability may induce physiological effects that enhance endurance exercise performance....
Activation of the sweet taste receptor T1R3 by sucralose attenuates VEGF-induced vasculogenesis in a cell model of the retinal microvascular endothelium
Graefes Arch Clin Exp Ophthalmol. 2019 Jan;257(1):71-81. doi: 10.1007/s00417-018-4157-8. Epub 2018 Oct 23. ABSTRACT BACKGROUND: One of the most prevalent microvascular complications for patients with...
Activation of the sweet taste receptor, T1R3, by the artificial sweetener sucralose regulates the pulmonary endothelium
Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L165-L176. doi: 10.1152/ajplung.00490.2016. Epub 2017 Sep 28. ABSTRACT A hallmark of acute respiratory distress syndrome (ARDS)...
Effect of fructose and sucralose on flow-mediated vasodilatation in healthy, white European males
J Pak Med Assoc. 2014 Jul;64(7):743-7. ABSTRACT OBJECTIVE: To assess how acute consumption of fructose affects flow-mediated dilatation in brachial artery. METHODS: The randomised cross-over...
Saccharin and Sucralose Protect the Glomerular Microvasculature In Vitro against VEGF-Induced Permeability
Nutrients. 2021 Aug 10;13(8):2746. doi: 10.3390/nu13082746. ABSTRACT Diabetic kidney disease (DKD) has become a global health concern, with about 40% of people living with type...
L-Arginine protects cementoblasts against hypoxia-induced apoptosis through Sirt1-enhanced autophagy
J Periodontol. 2021 Dec 26. doi: 10.1002/JPER.21-0473. Online ahead of print. ABSTRACT BACKGROUND: L-Arginine (L-arg) can reduce apoptosis in a variety of cells. Cementoblast apoptosis...