Preparing Medicinal Cannabis for Serious and Complex Illness
By Patrick Blanchard, M.D. Many people who visit a cannabis dispensary for the first time are scared and confused but it’s not their fault. The...
A behavioral and molecular study; ameliorated anxiety-like behavior and cognitive dysfunction in a rat model of chronic unpredictable stress treated with oregano extract
Brain Behav. 2022 Jul 27:e2727. doi: 10.1002/brb3.2727. Online ahead of print. ABSTRACT OBJECTIVE: Chronic stress is considered a severe risk factor leading to various disorders,...
Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies
PLoS One. 2022 Jun 29;17(6):e0270123. doi: 10.1371/journal.pone.0270123. eCollection 2022. ABSTRACT Aging-induced memory impairment is closely associated with oxidative stress. D-Galactose (D-gal) evokes severe oxidative stress...
Effects of curcumin and γ-oryzanol solid dispersion on the brain of middle-aged rats
Biomed Rep. 2022 May 26;17(1):59. doi: 10.3892/br.2022.1542. eCollection 2022 Jul. ABSTRACT Oxidative stress is one of the major factors that contributes to brain deterioration in...
Effect of Long-term Intake of Nutritive and Non-nutritive Sweeteners on Metabolic Health and Cognition in Adult Male Rats
J Med Food. 2022 Aug 11. doi: 10.1089/jmf.2022.0016. Online ahead of print. ABSTRACT This study evaluated the effects of long-term intake of nutritive sweeteners (NSs)...
A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease
Medicine (Baltimore). 2022 Aug 26;101(34):e30194. doi: 10.1097/MD.0000000000030194. ABSTRACT BACKGROUND: Alzheimer disease (AD) is a degenerative brain disease, which may lead to severe memory loss and...
Treatment of radiation-induced brain injury with bisdemethoxycurcumin
Neural Regen Res. 2023 Feb;18(2):416-421. doi: 10.4103/1673-5374.346549. ABSTRACT Radiation therapy is considered the most effective non-surgical treatment for brain tumors. However, there are no available...
Standardization and Ameliorative effect of Kalyanaka ghrita in β-amyloid induced memory impairment in wistar rats
J Ethnopharmacol. 2022 Aug 30:115671. doi: 10.1016/j.jep.2022.115671. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Kalyanaka ghrita (KG) is an Ayurvedic formulation traditionally used in the...
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems
Drug Chem Toxicol. 2022 Sep 7:1-9. doi: 10.1080/01480545.2022.2119995. Online ahead of print. ABSTRACT One of the well-established models for examining neurodegeneration and neurotoxicity is the...
Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Foods. 2022 Sep 2;11(17):2678. doi: 10.3390/foods11172678. ABSTRACT Due to great demand for memory enhancers, the memory-enhancing effects and the possible underlying mechanisms of the functional...
Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Foods. 2022 Sep 2;11(17):2678. doi: 10.3390/foods11172678. ABSTRACT Due to great demand for memory enhancers, the memory-enhancing effects and the possible underlying mechanisms of the functional...
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
Behav Pharmacol. 2022 Sep 13. doi: 10.1097/FBP.0000000000000694. Online ahead of print. ABSTRACT The effect of curcumin (Cur) on cognitive impairment and the possible role of...
Early life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats
JCI Insight. 2022 Sep 13:e157714. doi: 10.1172/jci.insight.157714. Online ahead of print. ABSTRACT Low-calorie sweetener (LCS) consumption in children has increased dramatically due to widespread presence...
Study protocol to determine the effects of highly absorbable oral curcumin on the indicators of cognitive functioning: a double-blind randomised controlled trial
BMJ Open. 2022 Sep 19;12(9):e057936. doi: 10.1136/bmjopen-2021-057936. ABSTRACT INTRODUCTION: Mild cognitive impairment (MCI) refers to a state in which cognitive functions, such as memory, have...
Neuroprotective effects of Shogaol in metals (Al, As and Pb) and high fat diet induced neuroinflammation and behavior in mice
Curr Mol Pharmacol. 2022 Sep 28. doi: 10.2174/1874467215666220928110557. Online ahead of print. ABSTRACT BACKGROUND: Increased exposure of humans to toxic metals and high fat diet...