A Proposed Association between Improving Energy Metabolism of HepG2 Cells by Plant Extracts and Increasing Their Sensitivity to Doxorubicin
Toxics. 2023 Feb 16;11(2):182. doi: 10.3390/toxics11020182. ABSTRACT Increasing cancer cell sensitivity to chemotherapy by amending aberrant metabolism using plant extracts represents a promising strategy to...
Acyl-CoA-dependent and acyl-CoA-independent avocado acyltransferases positively influence oleic acid content in nonseed triacylglycerols
Front Plant Sci. 2023 Jan 11;13:1056582. doi: 10.3389/fpls.2022.1056582. eCollection 2022. ABSTRACT In higher plants, acyl-CoA:diacylglycerol acyltransferase (DGAT) and phospholipid:diacylglycerol acyltransferase (PDAT) catalyze the terminal step...
Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat-High fructose diet
Front Pharmacol. 2022 Dec 19;13:1089130. doi: 10.3389/fphar.2022.1089130. eCollection 2022. ABSTRACT Non-alcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation in hepatocytes, and in advanced...
Bicarbonates and carbonates as antioxidants in vegetable oils at frying temperatures
J Food Sci. 2022 Dec 28. doi: 10.1111/1750-3841.16442. Online ahead of print. ABSTRACT Antioxidant activity of bicarbonates and carbonates including NaHCO3 , Na2 CO3 ,...
Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies
PLoS One. 2022 Jun 29;17(6):e0270123. doi: 10.1371/journal.pone.0270123. eCollection 2022. ABSTRACT Aging-induced memory impairment is closely associated with oxidative stress. D-Galactose (D-gal) evokes severe oxidative stress...
Effects of curcumin and γ-oryzanol solid dispersion on the brain of middle-aged rats
Biomed Rep. 2022 May 26;17(1):59. doi: 10.3892/br.2022.1542. eCollection 2022 Jul. ABSTRACT Oxidative stress is one of the major factors that contributes to brain deterioration in...
A behavioral and molecular study; ameliorated anxiety-like behavior and cognitive dysfunction in a rat model of chronic unpredictable stress treated with oregano extract
Brain Behav. 2022 Jul 27:e2727. doi: 10.1002/brb3.2727. Online ahead of print. ABSTRACT OBJECTIVE: Chronic stress is considered a severe risk factor leading to various disorders,...
Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Foods. 2022 Sep 2;11(17):2678. doi: 10.3390/foods11172678. ABSTRACT Due to great demand for memory enhancers, the memory-enhancing effects and the possible underlying mechanisms of the functional...
Treatment of radiation-induced brain injury with bisdemethoxycurcumin
Neural Regen Res. 2023 Feb;18(2):416-421. doi: 10.4103/1673-5374.346549. ABSTRACT Radiation therapy is considered the most effective non-surgical treatment for brain tumors. However, there are no available...
A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease
Medicine (Baltimore). 2022 Aug 26;101(34):e30194. doi: 10.1097/MD.0000000000030194. ABSTRACT BACKGROUND: Alzheimer disease (AD) is a degenerative brain disease, which may lead to severe memory loss and...
Standardization and Ameliorative effect of Kalyanaka ghrita in β-amyloid induced memory impairment in wistar rats
J Ethnopharmacol. 2022 Aug 30:115671. doi: 10.1016/j.jep.2022.115671. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Kalyanaka ghrita (KG) is an Ayurvedic formulation traditionally used in the...
Effect of Long-term Intake of Nutritive and Non-nutritive Sweeteners on Metabolic Health and Cognition in Adult Male Rats
J Med Food. 2022 Aug 11. doi: 10.1089/jmf.2022.0016. Online ahead of print. ABSTRACT This study evaluated the effects of long-term intake of nutritive sweeteners (NSs)...
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems
Drug Chem Toxicol. 2022 Sep 7:1-9. doi: 10.1080/01480545.2022.2119995. Online ahead of print. ABSTRACT One of the well-established models for examining neurodegeneration and neurotoxicity is the...
Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Foods. 2022 Sep 2;11(17):2678. doi: 10.3390/foods11172678. ABSTRACT Due to great demand for memory enhancers, the memory-enhancing effects and the possible underlying mechanisms of the functional...
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
Behav Pharmacol. 2022 Sep 13. doi: 10.1097/FBP.0000000000000694. Online ahead of print. ABSTRACT The effect of curcumin (Cur) on cognitive impairment and the possible role of...