A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease
Medicine (Baltimore). 2022 Aug 26;101(34):e30194. doi: 10.1097/MD.0000000000030194. ABSTRACT BACKGROUND: Alzheimer disease (AD) is a degenerative brain disease, which may lead to severe memory loss and...
Standardization and Ameliorative effect of Kalyanaka ghrita in β-amyloid induced memory impairment in wistar rats
J Ethnopharmacol. 2022 Aug 30:115671. doi: 10.1016/j.jep.2022.115671. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Kalyanaka ghrita (KG) is an Ayurvedic formulation traditionally used in the...
Effect of Long-term Intake of Nutritive and Non-nutritive Sweeteners on Metabolic Health and Cognition in Adult Male Rats
J Med Food. 2022 Aug 11. doi: 10.1089/jmf.2022.0016. Online ahead of print. ABSTRACT This study evaluated the effects of long-term intake of nutritive sweeteners (NSs)...
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems
Drug Chem Toxicol. 2022 Sep 7:1-9. doi: 10.1080/01480545.2022.2119995. Online ahead of print. ABSTRACT One of the well-established models for examining neurodegeneration and neurotoxicity is the...
Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Foods. 2022 Sep 2;11(17):2678. doi: 10.3390/foods11172678. ABSTRACT Due to great demand for memory enhancers, the memory-enhancing effects and the possible underlying mechanisms of the functional...
Treatment of radiation-induced brain injury with bisdemethoxycurcumin
Neural Regen Res. 2023 Feb;18(2):416-421. doi: 10.4103/1673-5374.346549. ABSTRACT Radiation therapy is considered the most effective non-surgical treatment for brain tumors. However, there are no available...
Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Foods. 2022 Sep 2;11(17):2678. doi: 10.3390/foods11172678. ABSTRACT Due to great demand for memory enhancers, the memory-enhancing effects and the possible underlying mechanisms of the functional...
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
Behav Pharmacol. 2022 Sep 13. doi: 10.1097/FBP.0000000000000694. Online ahead of print. ABSTRACT The effect of curcumin (Cur) on cognitive impairment and the possible role of...
Early life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats
JCI Insight. 2022 Sep 13:e157714. doi: 10.1172/jci.insight.157714. Online ahead of print. ABSTRACT Low-calorie sweetener (LCS) consumption in children has increased dramatically due to widespread presence...
Study protocol to determine the effects of highly absorbable oral curcumin on the indicators of cognitive functioning: a double-blind randomised controlled trial
BMJ Open. 2022 Sep 19;12(9):e057936. doi: 10.1136/bmjopen-2021-057936. ABSTRACT INTRODUCTION: Mild cognitive impairment (MCI) refers to a state in which cognitive functions, such as memory, have...
Neuroprotective effects of Shogaol in metals (Al, As and Pb) and high fat diet induced neuroinflammation and behavior in mice
Curr Mol Pharmacol. 2022 Sep 28. doi: 10.2174/1874467215666220928110557. Online ahead of print. ABSTRACT BACKGROUND: Increased exposure of humans to toxic metals and high fat diet...
Quercetin ameliorates memory impairment by inhibiting abnormal microglial activation in a mouse model of paradoxical sleep deprivation
Biochem Biophys Res Commun. 2022 Sep 27;632:10-16. doi: 10.1016/j.bbrc.2022.09.088. Online ahead of print. ABSTRACT Paradoxical sleep deprivation (PSD) is prevalent in modern society, and impaired...
Herbal tea with bacoside loaded saponins: formulation and characterization for food fortification from Bacopa monnieri L
J Food Sci Technol. 2022 Nov;59(11):4510-4519. doi: 10.1007/s13197-022-05532-y. Epub 2022 Jun 28. ABSTRACT In recent times, there is a renewed interest of herbal tea because...
The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease
Front Aging Neurosci. 2022 Oct 17;14:1022821. doi: 10.3389/fnagi.2022.1022821. eCollection 2022. ABSTRACT Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, affecting more than 55 million...
Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling
World J Gastroenterol. 2022 Oct 28;28(40):5865-5880. doi: 10.3748/wjg.v28.i40.5865. ABSTRACT BACKGROUND: Immune dysfunction is the crucial cause in the pathogenesis of inflammatory bowel disease (IBD), which...