Metabolism and Bioavailability of Olive Bioactive Constituents Based on In Vitro, In Vivo and Human Studies
Nutrients. 2022 Sep 13;14(18):3773. doi: 10.3390/nu14183773. ABSTRACT Consumption of olive products has been established as a health-promoting dietary pattern due to their high content in...
Characterization, stability, digestion and absorption of a nobiletin nanoemulsion using DHA-enriched phosphatidylcholine as an emulsifier in vivo and in vitro
Food Chem. 2022 Dec 15;397:133787. doi: 10.1016/j.foodchem.2022.133787. Epub 2022 Jul 29. ABSTRACT The emulsification ability of phospholipids might be associated with fatty acid composition. However,...
Assessing the bioavailability of polyphenols and antioxidant properties of extra virgin argan oil by simulated digestion and Caco-2 cell assays. Comparative study with extra virgin olive oil
Food Chem. 2015 Dec 1;188:496-503. doi: 10.1016/j.foodchem.2015.05.006. Epub 2015 May 8. ABSTRACT Argan oil is becoming increasingly popular in the edible-oil market as a luxury...
Design of the interface of edible nanoemulsions to modulate the bioaccessibility of neuroprotective antioxidants
Int J Pharm. 2015 Jul 25;490(1-2):209-18. doi: 10.1016/j.ijpharm.2015.05.031. Epub 2015 May 18. ABSTRACT Most frequently the use of bioactive molecules for the supplementation of food...
Metabolic fate (absorption, β-oxidation and deposition) of long-chain n-3 fatty acids is affected by sex and by the oil source (krill oil or fish oil) in the rat
Br J Nutr. 2015 Sep 14;114(5):684-92. doi: 10.1017/S0007114515002457. Epub 2015 Aug 3. ABSTRACT The effects of krill oil as an alternative source of n-3 long-chain...
Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments
Eur J Pharm Biopharm. 2015 Oct;96:207-16. doi: 10.1016/j.ejpb.2015.07.014. Epub 2015 Jul 26. ABSTRACT Novel formulations that overcome the solubility limitations of poorly water soluble drugs...
Dietary Components Affect the Plasma and Tissue Levels of Lutein in Aged Rats with Lutein Deficiency–A Repeated Gavage and Dietary Study
J Food Sci. 2015 Oct;80(10):H2322-30. doi: 10.1111/1750-3841.13007. Epub 2015 Sep 25. ABSTRACT The aim of this study was to find out the influence of selected...
Gender differences in plasma and urine metabolites from Sprague-Dawley rats after oral administration of normal and high doses of hydroxytyrosol, hydroxytyrosol acetate, and DOPAC
Eur J Nutr. 2017 Feb;56(1):215-224. doi: 10.1007/s00394-015-1071-2. Epub 2015 Oct 13. ABSTRACT PURPOSE: To date, several in vitro and in vivo studies have shown phenolic...
The clinical relevance of omega-3 fatty acids in the management of hypertriglyceridemia
Lipids Health Dis. 2016 Jul 22;15(1):118. doi: 10.1186/s12944-016-0286-4. ABSTRACT Hypertriglyceridemia (triglycerides > 150 mg/dL) affects ~25 % of the United States (US) population and is...
Bioavailability of tomato polyphenols is enhanced by processing and fat addition: Evidence from a randomized feeding trial
Mol Nutr Food Res. 2016 Jul;60(7):1578-89. doi: 10.1002/mnfr.201500820. Epub 2016 May 9. ABSTRACT SCOPE: Tomato contains a variety of phenolics associated with health-promoting properties. However,...
Nanoemulsifying drug delivery system to improve the bioavailability of piroxicam
Pharm Dev Technol. 2017 May;22(3):445-456. doi: 10.1080/10837450.2016.1231810. Epub 2016 Oct 25. ABSTRACT OBJECTIVE: The aim of this study is to develop and characterize self-nanoemulsifying drug...
Microemulsions containing long-chain oil ethyl oleate improve the oral bioavailability of piroxicam by increasing drug solubility and lymphatic transportation simultaneously
Int J Pharm. 2016 Sep 25;511(2):709-18. doi: 10.1016/j.ijpharm.2016.07.061. Epub 2016 Jul 26. ABSTRACT Drug solubility and lymphatic transport enhancements are two main pathways to improve...
The influence of lipid droplet size on the oral bioavailability of vitamin D2 encapsulated in emulsions: an in vitro and in vivo study
Food Funct. 2017 Feb 22;8(2):767-777. doi: 10.1039/c6fo01565d. ABSTRACT Vitamin D deficiency is prevalent in some populations leading to adverse health effects, and therefore there is...
Dietary intake of n-3 PUFAs modifies the absorption, distribution and bioavailability of fatty acids in the mouse gastrointestinal tract
Lipids Health Dis. 2017 Jan 17;16(1):10. doi: 10.1186/s12944-016-0399-9. ABSTRACT BACKGROUND: Dietary polyunsaturated fatty acids (PUFAs), especially n-3 PUFAs, are important for human health. The intestinal...
Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption
Lipids. 2016 Oct;51(10):1137-1144. doi: 10.1007/s11745-016-4189-y. Epub 2016 Sep 7. ABSTRACT Oil from the marine copepod, Calanus finmarchicus, which contains >86 % of fatty acids present...