Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies
PLoS One. 2022 Jun 29;17(6):e0270123. doi: 10.1371/journal.pone.0270123. eCollection 2022. ABSTRACT Aging-induced memory impairment is closely associated with oxidative stress. D-Galactose (D-gal) evokes severe oxidative stress...
Effects of curcumin and γ-oryzanol solid dispersion on the brain of middle-aged rats
Biomed Rep. 2022 May 26;17(1):59. doi: 10.3892/br.2022.1542. eCollection 2022 Jul. ABSTRACT Oxidative stress is one of the major factors that contributes to brain deterioration in...
Treatment of radiation-induced brain injury with bisdemethoxycurcumin
Neural Regen Res. 2023 Feb;18(2):416-421. doi: 10.4103/1673-5374.346549. ABSTRACT Radiation therapy is considered the most effective non-surgical treatment for brain tumors. However, there are no available...
A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease
Medicine (Baltimore). 2022 Aug 26;101(34):e30194. doi: 10.1097/MD.0000000000030194. ABSTRACT BACKGROUND: Alzheimer disease (AD) is a degenerative brain disease, which may lead to severe memory loss and...
Standardization and Ameliorative effect of Kalyanaka ghrita in β-amyloid induced memory impairment in wistar rats
J Ethnopharmacol. 2022 Aug 30:115671. doi: 10.1016/j.jep.2022.115671. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Kalyanaka ghrita (KG) is an Ayurvedic formulation traditionally used in the...
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems
Drug Chem Toxicol. 2022 Sep 7:1-9. doi: 10.1080/01480545.2022.2119995. Online ahead of print. ABSTRACT One of the well-established models for examining neurodegeneration and neurotoxicity is the...
Study protocol to determine the effects of highly absorbable oral curcumin on the indicators of cognitive functioning: a double-blind randomised controlled trial
BMJ Open. 2022 Sep 19;12(9):e057936. doi: 10.1136/bmjopen-2021-057936. ABSTRACT INTRODUCTION: Mild cognitive impairment (MCI) refers to a state in which cognitive functions, such as memory, have...
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
Behav Pharmacol. 2022 Sep 13. doi: 10.1097/FBP.0000000000000694. Online ahead of print. ABSTRACT The effect of curcumin (Cur) on cognitive impairment and the possible role of...
Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling
World J Gastroenterol. 2022 Oct 28;28(40):5865-5880. doi: 10.3748/wjg.v28.i40.5865. ABSTRACT BACKGROUND: Immune dysfunction is the crucial cause in the pathogenesis of inflammatory bowel disease (IBD), which...
Protection against Morphine-Induced Inhibitory Avoidance Memory Impairment in Rat by Curcumin: Possible Role of Nitric Oxide/ cAMP-Response Element Binding Protein Pathway
Iran J Med Sci. 2022 Nov;47(6):594-602. doi: 10.30476/IJMS.2022.92131.2339. ABSTRACT BACKGROUND: Although a substantial body of research suggests curcumin (CUR) has the preventive potential in memory...
The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease
Front Aging Neurosci. 2022 Oct 17;14:1022821. doi: 10.3389/fnagi.2022.1022821. eCollection 2022. ABSTRACT Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, affecting more than 55 million...
Efficacy of Curcumin-Mediated Photodynamic Therapy for Root Canal Therapy Procedures: A Systematic Review
Photodiagnosis Photodyn Ther. 2022 Dec 20:103252. doi: 10.1016/j.pdpdt.2022.103252. Online ahead of print. ABSTRACT BACKGROUND: This systematic review aimed to investigate the effectiveness of CUR-mediated PDT...
Curcumin Regulates Gut Microbiota and Exerts a Neuroprotective Effect in the MPTP Model of Parkinson’s Disease
Evid Based Complement Alternat Med. 2022 Nov 24;2022:9110560. doi: 10.1155/2022/9110560. eCollection 2022. NO ABSTRACT PMID:36467550 | PMC:PMC9715342 | DOI:10.1155/2022/9110560...
Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1
ACS Omega. 2022 Nov 14;7(47):43290-43305. doi: 10.1021/acsomega.2c06215. eCollection 2022 Nov 29. NO ABSTRACT PMID:36467923 | PMC:PMC9713875 | DOI:10.1021/acsomega.2c06215...
Dietary curcumin supplementation relieves hydrogen peroxide-induced testicular injury by antioxidant and anti-apoptotic effects in roosters
Theriogenology. 2022 Nov 5;197:46-56. doi: 10.1016/j.theriogenology.2022.10.038. Online ahead of print. NO ABSTRACT PMID:36470109 | DOI:10.1016/j.theriogenology.2022.10.038...