Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies
PLoS One. 2022 Jun 29;17(6):e0270123. doi: 10.1371/journal.pone.0270123. eCollection 2022. ABSTRACT Aging-induced memory impairment is closely associated with oxidative stress. D-Galactose (D-gal) evokes severe oxidative stress...
Effects of curcumin and γ-oryzanol solid dispersion on the brain of middle-aged rats
Biomed Rep. 2022 May 26;17(1):59. doi: 10.3892/br.2022.1542. eCollection 2022 Jul. ABSTRACT Oxidative stress is one of the major factors that contributes to brain deterioration in...
Treatment of radiation-induced brain injury with bisdemethoxycurcumin
Neural Regen Res. 2023 Feb;18(2):416-421. doi: 10.4103/1673-5374.346549. ABSTRACT Radiation therapy is considered the most effective non-surgical treatment for brain tumors. However, there are no available...
A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease
Medicine (Baltimore). 2022 Aug 26;101(34):e30194. doi: 10.1097/MD.0000000000030194. ABSTRACT BACKGROUND: Alzheimer disease (AD) is a degenerative brain disease, which may lead to severe memory loss and...
Standardization and Ameliorative effect of Kalyanaka ghrita in β-amyloid induced memory impairment in wistar rats
J Ethnopharmacol. 2022 Aug 30:115671. doi: 10.1016/j.jep.2022.115671. Online ahead of print. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Kalyanaka ghrita (KG) is an Ayurvedic formulation traditionally used in the...
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems
Drug Chem Toxicol. 2022 Sep 7:1-9. doi: 10.1080/01480545.2022.2119995. Online ahead of print. ABSTRACT One of the well-established models for examining neurodegeneration and neurotoxicity is the...
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
Behav Pharmacol. 2022 Sep 13. doi: 10.1097/FBP.0000000000000694. Online ahead of print. ABSTRACT The effect of curcumin (Cur) on cognitive impairment and the possible role of...
Study protocol to determine the effects of highly absorbable oral curcumin on the indicators of cognitive functioning: a double-blind randomised controlled trial
BMJ Open. 2022 Sep 19;12(9):e057936. doi: 10.1136/bmjopen-2021-057936. ABSTRACT INTRODUCTION: Mild cognitive impairment (MCI) refers to a state in which cognitive functions, such as memory, have...
The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease
Front Aging Neurosci. 2022 Oct 17;14:1022821. doi: 10.3389/fnagi.2022.1022821. eCollection 2022. ABSTRACT Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, affecting more than 55 million...
Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling
World J Gastroenterol. 2022 Oct 28;28(40):5865-5880. doi: 10.3748/wjg.v28.i40.5865. ABSTRACT BACKGROUND: Immune dysfunction is the crucial cause in the pathogenesis of inflammatory bowel disease (IBD), which...
Protection against Morphine-Induced Inhibitory Avoidance Memory Impairment in Rat by Curcumin: Possible Role of Nitric Oxide/ cAMP-Response Element Binding Protein Pathway
Iran J Med Sci. 2022 Nov;47(6):594-602. doi: 10.30476/IJMS.2022.92131.2339. ABSTRACT BACKGROUND: Although a substantial body of research suggests curcumin (CUR) has the preventive potential in memory...
Efficacy of Curcumin-Mediated Photodynamic Therapy for Root Canal Therapy Procedures: A Systematic Review
Photodiagnosis Photodyn Ther. 2022 Dec 20:103252. doi: 10.1016/j.pdpdt.2022.103252. Online ahead of print. ABSTRACT BACKGROUND: This systematic review aimed to investigate the effectiveness of CUR-mediated PDT...
Curcumin Regulates Gut Microbiota and Exerts a Neuroprotective Effect in the MPTP Model of Parkinson’s Disease
Evid Based Complement Alternat Med. 2022 Nov 24;2022:9110560. doi: 10.1155/2022/9110560. eCollection 2022. NO ABSTRACT PMID:36467550 | PMC:PMC9715342 | DOI:10.1155/2022/9110560...
Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1
ACS Omega. 2022 Nov 14;7(47):43290-43305. doi: 10.1021/acsomega.2c06215. eCollection 2022 Nov 29. NO ABSTRACT PMID:36467923 | PMC:PMC9713875 | DOI:10.1021/acsomega.2c06215...
Dietary curcumin supplementation relieves hydrogen peroxide-induced testicular injury by antioxidant and anti-apoptotic effects in roosters
Theriogenology. 2022 Nov 5;197:46-56. doi: 10.1016/j.theriogenology.2022.10.038. Online ahead of print. NO ABSTRACT PMID:36470109 | DOI:10.1016/j.theriogenology.2022.10.038...