Multi-Pathway Microenvironment Regulation for Atherosclerosis Therapy Based on Beta-Cyclodextrin/L-Arginine/Au Nanomotors with Dual-Mode Propulsion
Small. 2021 Dec 16:e2104120. doi: 10.1002/smll.202104120. Online ahead of print. ABSTRACT Most of the current non-pharmacological treatment strategies for atherosclerosis (AS) suffer from poor penetration...
The role of L-arginine metabolism in neurocritical care patients
Neural Regen Res. 2022 Jul;17(7):1446-1453. doi: 10.4103/1673-5374.327331. ABSTRACT Nitric oxide is an important mediator of vascular autoregulation and is involved in pathophysiological changes after acute...
Contributions of Endothelin-1 and L-arginine to Blunted Cutaneous Microvascular Function in Young, Black Women
Am J Physiol Heart Circ Physiol. 2021 Dec 17. doi: 10.1152/ajpheart.00457.2021. Online ahead of print. ABSTRACT Non-Hispanic black (BL) individuals have the greatest prevalence of...
Analysis of serum levels L-arginine and 25-hydroxyvitamin D as a predictor of survival of severe preeclampsia mothers
Gac Sanit. 2021;35 Suppl 2:S224-S226. doi: 10.1016/j.gaceta.2021.10.026. ABSTRACT OBJECTIVE: This study aimed to analyze serum levels of L-arginine and 25-hydroxyvitamin D as predictors of survival...
l-Arginine Alleviates LPS-Induced Oxidative Stress and Apoptosis via Activating SIRT1-AKT-Nrf2 and SIRT1-FOXO3a Signaling Pathways in C2C12 Myotube Cells
Antioxidants (Basel). 2021 Dec 7;10(12):1957. doi: 10.3390/antiox10121957. ABSTRACT l-arginine (l-Arg) has been reported to possess a wide range of functions, including anti-inflammatory, anti-oxidative, and anti-apoptosis....
L-Arginine Supplementation for Nulliparous Sows during the Last Third of Gestation
Animals (Basel). 2021 Dec 6;11(12):3476. doi: 10.3390/ani11123476. ABSTRACT We evaluated the effects of L-arginine supplementation during the last third of gestation on molecular mechanisms related...
The Role of the pH in the Impregnation of Spherical Mesoporous Silica Particles with L-Arginine Aqueous Solutions
Int J Mol Sci. 2021 Dec 14;22(24):13403. doi: 10.3390/ijms222413403. ABSTRACT In the context of the development of carriers for amino acids delivery, Spherical Mesoporous Silica...
Reversal of Stroke-Like Episodes With L-Arginine and Meticulous Perioperative Management of Renal Transplantation in a Patient With Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS) Syndrome. Case Report
Neurohospitalist. 2022 Jan;12(1):67-73. doi: 10.1177/19418744211000512. Epub 2021 Mar 15. ABSTRACT Mitochondrial encephalomyopathy, lactic acidosis and stroke like episodes (MELAS) syndrome is a maternally inherited mitochondrial...
Nutraceuticals in the Management of Cardiovascular Risk Factors: Where is the Evidence?
Cardiovasc Hematol Disord Drug Targets. 2021 Nov 30. doi: 10.2174/1871529X21666211201104124. Online ahead of print. ABSTRACT Cardiovascular disease continues to rise at an alarming rate, and...
Erythritol modulates the polarization of macrophages: Potential role of tumor necrosis factor-alpha and Akt pathway
J Food Biochem. 2021 Dec 19:e13960. doi: 10.1111/jfbc.13960. Online ahead of print. ABSTRACT Low-calorie sweeteners are substitutes for sugar and frequently used by patients with...
An insight on the future therapeutic application potential of Stevia rebaudiana Bertoni for atherosclerosis and cardiovascular diseases
Biomed Pharmacother. 2021 Nov;143:112207. doi: 10.1016/j.biopha.2021.112207. Epub 2021 Sep 23. ABSTRACT Stevia rebaudiana Bertoni is a native plant to Paraguay. The extracts have been used...
Inhibitory effect of stevioside on calcium influx to produce antihypertension
Planta Med. 2001 Dec;67(9):796-9. doi: 10.1055/s-2001-18841. ABSTRACT Stevioside is a sweet-tasting glycoside occurring abundantly in the leaves of Stevia rebaudiana (Compositae). It has been used...
Isosteviol acts on potassium channels to relax isolated aortic strips of Wistar rat
Life Sci. 2004 Mar 26;74(19):2379-87. doi: 10.1016/j.lfs.2003.09.065. ABSTRACT Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly used as a...
Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults with ADPKD
Clin J Am Soc Nephrol. 2021 Dec 14:CJN.08950621. doi: 10.2215/CJN.08950621. Online ahead of print. ABSTRACT Background and Objectives: Clinical manifestations of autosomal dominant polycystic kidney...
Steroid-Induced Osteonecrosis of the Femoral Head: Novel Insight Into the Roles of Bone Endothelial Cells in Pathogenesis and Treatment
Front Cell Dev Biol. 2021 Nov 30;9:777697. doi: 10.3389/fcell.2021.777697. eCollection 2021. ABSTRACT Steroid-induced osteonecrosis of the femoral head (SONFH) is a disease characterized by the...