Vasoactive Properties of a Cocoa Shell Extract: Mechanism of Action and Effect on Endothelial Dysfunction in Aged Rats
Antioxidants (Basel). 2022 Feb 21;11(2):429. doi: 10.3390/antiox11020429. ABSTRACT Cocoa has cardiovascular beneficial effects related to its content of antioxidant phytochemicals. Cocoa manufacturing produces large amounts...
L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction
Biomedicines. 2022 Jan 18;10(2):205. doi: 10.3390/biomedicines10020205. ABSTRACT BACKGROUND: Spinal cord injury (SCI) elicits robust neuroinflammation that eventually exacerbates the initial damage to the spinal cord....
Icariin attenuates cyclophosphamide-induced cystitis via down-regulation of NF-B and up-regulation of Nrf-2/HO-1 signaling pathways in mice model
Int Immunopharmacol. 2022 Feb 8;106:108604. doi: 10.1016/j.intimp.2022.108604. Online ahead of print. ABSTRACT Cystitis is a chronic bladder pain associated with frequency and nocturia. In the...
Efficacy of Auricular Acupuncture and Lavender Oil Aromatherapy in Reducing Preinterventional Anxiety in Cardiovascular Patients: A Randomized Single-Blind Placebo-Controlled Trial
J Integr Complement Med. 2022 Jan;28(1):45-50. doi: 10.1089/jicm.2021.0171. ABSTRACT Introduction: Auricular acupuncture at the “relaxation point” and lavender oil aromatherapy can reduce preoperative anxiety associated...
Cutting Edge: L-Arginine Transfer from Antigen-Presenting Cells Sustains CD4(+) T Cell Viability and Proliferation
J Immunol. 2022 Jan 31:ji2100652. doi: 10.4049/jimmunol.2100652. Online ahead of print. ABSTRACT Metabolomics analyses suggest changes in amino acid abundance, particularly l-arginine (L-ARG), occur in...
Flavanol Consumption in Healthy Men Preserves Integrity of Immunological-Endothelial Barrier Cell Functions: Nutri(epi)genomic Analysis
Mol Nutr Food Res. 2022 Jan 30:e2100991. doi: 10.1002/mnfr.202100991. Online ahead of print. ABSTRACT SCOPE: While cocoa flavanol (CF) consumption improves cardiovascular risk biomarkers, molecular...
l-Arginine inhibits the activity of alpha-amylase: Rapid kinetics, interaction and functional implications
Food Chem. 2022 Jan 21;380:131836. doi: 10.1016/j.foodchem.2021.131836. Online ahead of print. ABSTRACT In this work, the rapid unfolding kinetics of pancreas α-amylase (PPA) induced by...
The Effects of L-Arginine in Hypertensive Patients: A Literature Review
Cureus. 2021 Dec 17;13(12):e20485. doi: 10.7759/cureus.20485. eCollection 2021 Dec. ABSTRACT Hypertension (HTN) is a chronic disease that affects more than 972 million people throughout the...
Dietary N-carbamylglutamate or L-arginine improves fetal intestinal amino acid profiles during intrauterine growth restriction in undernourished ewes
Anim Nutr. 2022 Mar;8(1):341-349. doi: 10.1016/j.aninu.2021.12.001. Epub 2021 Dec 27. ABSTRACT Our previous studies demonstrated that prenatal in utero growth restriction impairs postnatal intestinal function....
Effect of combined treatment of L-arginine and transglutaminase on the gelation behavior of freeze-damaged myofibrillar protein
Food Funct. 2022 Jan 21. doi: 10.1039/d1fo03691b. Online ahead of print. ABSTRACT This research focused on the effects of L-arginine (Arg, 5 mM), transglutaminase (TG,...
A Severe Acute Pancreatitis Mouse Model Transited from Mild Symptoms Induced by a “Two-Hit” Strategy with L-Arginine
Life (Basel). 2022 Jan 16;12(1):126. doi: 10.3390/life12010126. ABSTRACT To develop a severe acute pancreatitis (SAP) model transited from mild symptoms, we investigated a “two-hit” strategy...
Multifaceted functionality of L-arginine in modulating the emulsifying properties of pea protein isolate and the oxidation stability of its emulsions
Food Funct. 2022 Jan 18. doi: 10.1039/d1fo03372g. Online ahead of print. ABSTRACT The effects of L-arginine (Arg) at different concentrations (0%, 0.05%, 0.1%, 0.2%, 0.5%...
Paeoniflorin alleviates NG-nitro-L-arginine methyl ester (L-NAME)-induced gestational hypertension and upregulates silent information regulator 2 related enzyme 1 (SIRT1) to reduce H(2)O(2)-induced endothelial cell damage
Bioengineered. 2022 Feb;13(2):2248-2258. doi: 10.1080/21655979.2021.2024325. ABSTRACT Pregnancy-induced hypertension (PIH) is a leading cause of maternal mortality. Paeoniflorin has been reported to alleviate hypertension, thus relieving...
The effect of l-arginine supplementation and surgical trauma on the frequency of myeloid-derived suppressor cells and T lymphocytes in tumour and blood of colorectal cancer patients
Adv Med Sci. 2022 Jan 4;67(1):66-78. doi: 10.1016/j.advms.2021.12.005. Online ahead of print. ABSTRACT PURPOSE: l-arginine (L-arg) deficiency causes immunosuppression, but it is unknown if L-arg...
A study of lovastatin and L-arginine co-loaded PLGA nanomedicine for enhancing nitric oxide production and eNOS expression
J Mater Chem B. 2022 Jan 7. doi: 10.1039/d1tb01455b. Online ahead of print. ABSTRACT Nitric oxide (NO) is an exceptional endogenous biological gas that mediates...