Protective Effect of L-Arginine in an Animal Model of Alzheimer’s Disease Induced by Intra-Hippocampal Injection of AlCl3
Neurol India. 2022 Mar-Apr;70(2):548-553. doi: 10.4103/0028-3886.344672. ABSTRACT BACKGROUND AND OBJECTIVE: Aluminum chloride (AlCl3) can impair spatial memory recovery. We investigated the protective effect of L-arginine,...
Protective effects of L-arginine on cognitive deficits and biochemical parameters in an experimental model of type-2 diabetes mellitus induced Alzheimer’s disease in rats
J Physiol Pharmacol. 2022 Feb;73(1). doi: 10.26402/jpp.2022.1.01. Epub 2022 May 27. ABSTRACT Alzheimer’s disease (AD) has been closely linked to type 2 diabetes mellitus (T2DM)...
Prevention of Bortezomib-Induced Peripheral Neuropathy in Newly Multiple Myeloma Patients Using Nervonic Acid, Curcuma Rizoma, and L-Arginine Compound: A Pilot Study
Integr Cancer Ther. 2022 Jan-Dec;21:15347354221114142. doi: 10.1177/15347354221114142. ABSTRACT INTRODUCTION: This is a phase II pilot study to evaluate the efficacy of a nutraceutical compound composed...
Antioxidant and Neuroprotective Effects of L-arginine Administration After Traumatic Brain Injury and Hemorrhagic Shock in Rats
Turk Neurosurg. 2022 Feb 2. doi: 10.5137/1019-5149.JTN.35263-21.2. Online ahead of print. ABSTRACT AIM: The aim of the current study was to investigate the effect of...
Benefits of Curcumin in the Vasculature: A Therapeutic Candidate for Vascular Remodeling in Arterial Hypertension and Pulmonary Arterial Hypertension?
Front Physiol. 2022 Apr 1;13:848867. doi: 10.3389/fphys.2022.848867. eCollection 2022. ABSTRACT Growing evidence suggests that hypertension is one of the leading causes of cardiovascular morbidity and...
Individual effects of rosemary extract and green tea polyphenols on the physicochemical properties of soybean oil-myosin emulsion with l-arginine or l-lysine
Food Chem. 2022 Jun 27;395:133582. doi: 10.1016/j.foodchem.2022.133582. Online ahead of print. ABSTRACT This study aimed to investigate the individual effects of rosemary extract and green...
Enhanced protein aggregation suppressor activity of N-acetyl-l-arginine for agitation-induced aggregation with silicone oil and its impact on innate immune responses
Int J Biol Macromol. 2022 Jun 29:S0141-8130(22)01389-7. doi: 10.1016/j.ijbiomac.2022.06.176. Online ahead of print. ABSTRACT Previously, N-acetyl-l-arginine (NALA) suppressed the aggregation of intravenous immunoglobulins (IVIG) more...
Red yeast rice for dyslipidaemias and cardiovascular risk reduction: A Position Paper of the International Lipid Expert Panel
Pharmacol Res. 2022 Jul 25:106370. doi: 10.1016/j.phrs.2022.106370. Online ahead of print. ABSTRACT The risk of atherosclerotic cardiovascular disease (ASCVD) is strongly related to lifetime exposure...
Chocolate and Cocoa-Derived Biomolecules for Brain Cognition during Ageing
Antioxidants (Basel). 2022 Jul 12;11(7):1353. doi: 10.3390/antiox11071353. ABSTRACT Cognitive decline is a common problem in older individuals, often exacerbated by neurocognitive conditions, such as vascular...
Acute Effects of Cocoa Flavanols on Blood Pressure and Peripheral Vascular Reactivity in Type 2 Diabetes Mellitus and Essential Hypertension
Nutrients. 2022 Jun 28;14(13):2692. doi: 10.3390/nu14132692. ABSTRACT BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with a high risk of vascular complications. Interestingly, cocoa flavanols...
Assessing Variability in Vascular Response to Cocoa With Personal Devices: A Series of Double-Blind Randomized Crossover n-of-1 Trials
Front Nutr. 2022 Jun 13;9:886597. doi: 10.3389/fnut.2022.886597. eCollection 2022. ABSTRACT Controlled clinical intervention studies have demonstrated that cocoa flavanols (CF) can decrease blood pressure and...
Dietary Bioflavanol Supplementation Does Not Improve Cold-Induced Vasodilation in Healthy Adults
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R3395. ABSTRACT BACKGROUND: Cold-induced vasodilation (CIVD) is a cyclical rise in blood flow to glabrous skin that occurs...
A descriptive study of commercial herbal dietary supplements used for dyslipidemia-Sales data and suspected adverse reactions
Phytother Res. 2022 May 7. doi: 10.1002/ptr.7473. Online ahead of print. ABSTRACT Herbal dietary supplements (HDS) used for dyslipidemia represent a category of concern in...
Effectiveness and safety of red yeast rice predominated by monacolin K β-hydroxy acid form for hyperlipidemia treatment and management
J Tradit Chin Med. 2022 Apr;42(2):264-271. doi: 10.19852/j.cnki.jtcm.2022.02.007. ABSTRACT OBJECTIVE: To assess the lipid-lowering activity and safety of a dietary supplement containing monacolin K β-hydroxy...
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases
Int J Mol Sci. 2022 Feb 15;23(4):2136. doi: 10.3390/ijms23042136. ABSTRACT INTRODUCTION: L-Arginine (Arg) is a semi-essential amino acid. Constitutive and inducible nitric oxide synthase (NOS)...