Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats
Exp Mol Pathol. 2022 Apr 7:104763. doi: 10.1016/j.yexmp.2022.104763. Online ahead of print. ABSTRACT BACKGROUND: A decrease in nitric oxide (NO) bioavailability has been shown to...
L-Arginine and Cardioactive Arginine Derivatives as Substrates and Inhibitors of Human and Mouse NaCT/Nact
Metabolites. 2022 Mar 22;12(4):273. doi: 10.3390/metabo12040273. ABSTRACT The uptake transporter NaCT (gene symbol SLC13A5) is expressed in liver and brain and important for energy metabolism...
Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas
Int J Mol Sci. 2022 Apr 15;23(8):4386. doi: 10.3390/ijms23084386. ABSTRACT Bacterial biofilm represents a multicellular community embedded within an extracellular matrix attached to a surface....
Eight Days of L-Citrulline or L-Arginine Supplementation Did Not Improve 200-m and 100-m Swimming Time Trials
Int J Environ Res Public Health. 2022 Apr 7;19(8):4462. doi: 10.3390/ijerph19084462. ABSTRACT The effects of L-citrulline or L-arginine supplementation on exercise performance are equivocal, and...
Poly-L-Arginine Molecule Properties in Simple Electrolytes: Molecular Dynamic Modeling and Experiments
Int J Environ Res Public Health. 2022 Mar 17;19(6):3588. doi: 10.3390/ijerph19063588. ABSTRACT Physicochemical properties of poly-L-arginine (P-Arg) molecules in NaCl solutions were determined by molecular...
Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice
Sci Rep. 2022 Mar 24;12(1):5108. doi: 10.1038/s41598-022-08846-1. ABSTRACT In humans and mice, L-arginine:glycine amidinotransferase (AGAT) and its metabolites homoarginine (hArg) and creatine have been linked...
l-Arginine and Beetroot Extract Supplementation in the Prevention of Sarcopenia
Pharmaceuticals (Basel). 2022 Feb 26;15(3):290. doi: 10.3390/ph15030290. ABSTRACT Aging is associated with a significant decline in neuromuscular function, leading to a reduction in muscle mass...
Research Note: Effects of dietary L-arginine on the production performance and gene expression of reproductive hormones in laying hens fed low crude protein diets
Poult Sci. 2022 Feb 25;101(5):101816. doi: 10.1016/j.psj.2022.101816. Online ahead of print. ABSTRACT The present study was designed to investigate whether L-arginine (Arg) supplementation would influence...
Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: From effects to molecular mechanisms
Biomed Pharmacother. 2022 Mar;147:112642. doi: 10.1016/j.biopha.2022.112642. Epub 2022 Jan 21. ABSTRACT Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among all types...
Effect of cocoa flavanol supplementation for prevention of cardiovascular disease events: The COSMOS randomized clinical trial
Am J Clin Nutr. 2022 Mar 16:nqac055. doi: 10.1093/ajcn/nqac055. Online ahead of print. ABSTRACT BACKGROUND: Cocoa extract is a source of flavanols that favorably influence...
Comparing the effectiveness of Chinese patent medicines containing red yeast rice on hyperlipidaemia: A network meta-analysis of randomized controlled trials
Endocrinol Diabetes Metab. 2022 Jan;5(1):e00314. doi: 10.1002/edm2.314. Epub 2021 Nov 11. ABSTRACT INTRODUCTION: The purpose of this study was to evaluate the therapeutic effectiveness of...
The Effect of Dietary Polyphenols on Vascular Health and Hypertension: Current Evidence and Mechanisms of Action
Nutrients. 2022 Jan 27;14(3):545. doi: 10.3390/nu14030545. ABSTRACT The aim of this review was to explore existing evidence from studies conducted on humans and summarize the...
Red Yeast Rice Preparations Reduce Mortality, Major Cardiovascular Adverse Events, and Risk Factors for Metabolic Syndrome: A Systematic Review and Meta-analysis
Front Pharmacol. 2022 Feb 21;13:744928. doi: 10.3389/fphar.2022.744928. eCollection 2022. ABSTRACT Background: Metabolic syndrome (MetS) is characterized by the cooccurrence of obesity, insulin resistance, dyslipidaemia, and...
Effects of monacolin K-containing nutraceutical on cholesterol homeostasis re-establishment and CVD risk reduction in hypercholesterolemic subjects
Eur Rev Med Pharmacol Sci. 2021 Aug;25(16):5261-5267. doi: 10.26355/eurrev_202108_26546. ABSTRACT OBJECTIVE: Hypercholesterolemia is caused by cholesterol homeostasis (CH) disruption, and it contributes to cardiovascular diseases...
Curcumin alleviates lipopolysaccharides-induced inflammation and apoptosis in vascular smooth muscle cells via inhibition of the NF-kappaB and JNK signaling pathways
Inflammopharmacology. 2022 Mar 1. doi: 10.1007/s10787-021-00912-w. Online ahead of print. ABSTRACT Curcumin plays an important role in inflammation regulation. This study aimed to investigate the...