Arbuscular Mycorrhizal Fungi-Mediated Modulation of Physiological, Biochemical, and Secondary Metabolite Responses in Hemp (Cannabis sativa L.) under Salt and Drought Stress
J Fungi (Basel). 2024 Apr 12;10(4):283. doi: 10.3390/jof10040283. ABSTRACT The increasing impact of global climate change has resulted in adversity stresses, like salt and drought,...
Assessment of Clinical Outcomes in Patients With Osteoarthritis: Analysis From the UK Medical Cannabis Registry
J Pain Palliat Care Pharmacother. 2024 Apr 26:1-14. doi: 10.1080/15360288.2024.2340076. Online ahead of print. ABSTRACT Osteoarthritis accounts for 0.6% of disability-adjusted life years globally. There...
Phytocannabinoids CBD, CBG, and their Derivatives CBD-HQ and CBG-A Induced In Vitro Cytotoxicity in 2D and 3D Colon Cancer Cell Models
Curr Issues Mol Biol. 2024 Apr 19;46(4):3626-3639. doi: 10.3390/cimb46040227. ABSTRACT Phytocannabinoids, compounds found in Cannabis sativa L., are used in oncology and palliative care to...
Interactions between Bacillus thuringiensis and selected plant extracts for sustainable management of Phthorimaea absoluta
Sci Rep. 2024 Apr 23;14(1):9299. doi: 10.1038/s41598-024-60140-4. ABSTRACT Phthorimaea absoluta is a global constraint to tomato production and can cause up to 100% yield loss....
Defining a public health approach to substance use: Perspectives from professionals and practitioners across Canada
Int J Drug Policy. 2024 Apr 24;128:104427. doi: 10.1016/j.drugpo.2024.104427. Online ahead of print. ABSTRACT BACKGROUND: While increasingly referenced in the literature and policy discussions, a...
Cannabis use and emergency department symptoms: Discordance between patient and provider perspectives
Am J Emerg Med. 2024 Apr 21:S0735-6757(24)00200-6. doi: 10.1016/j.ajem.2024.04.041. Online ahead of print. NO ABSTRACT PMID:38664105 | DOI:10.1016/j.ajem.2024.04.041...
Cannabis Use Characteristics Associated with Self-Reported Cognitive Function in a Nationally Representative U.S. sample
Subst Use Misuse. 2024 Apr 25:1-10. doi: 10.1080/10826084.2024.2340975. Online ahead of print. ABSTRACT BACKGROUND: With increases in cannabis use and potency, there is a need...
Assessing the preparedness and future-readiness of Malaysian community pharmacists in Klang Valley regarding the use of medical marijuana
BMC Health Serv Res. 2024 Apr 25;24(1):524. doi: 10.1186/s12913-024-11008-w. ABSTRACT BACKGROUND: This study investigated community pharmacists’ level of knowledge and attitude towards medical marijuana and...
Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft versus host disease
J Clin Invest. 2024 Apr 25:e175205. doi: 10.1172/JCI175205. Online ahead of print. ABSTRACT Neuroinflammation is a recognized complication of immunotherapeutic approaches such as immune checkpoint...
Carotenoid pattern intake and relation to metabolic status, risk and syndrome, and its components – divergent findings from the ORISCAV-LUX-2 survey
Br J Nutr. 2024 Apr 19:1-37. doi: 10.1017/S0007114524000758. Online ahead of print. ABSTRACT Carotenoids are generally associated with health-beneficial effects; however, their intake patterns related...
Biological characterization of Physostegia chlorotic mottle virus, an emergent virus infecting vegetables in diversified production systems
Phytopathology. 2024 Apr 22. doi: 10.1094/PHYTO-06-23-0194-R. Online ahead of print. ABSTRACT In 2014, Physostegia chlorotic mottle virus (PhCMoV) was discovered in Austria in Physostegia virginiana....
Indirect and direct cannabinoid agonists differentially affect mesolimbic dopamine release and related behaviors
Behav Neurosci. 2024 Apr;138(2):108-124. doi: 10.1037/bne0000582. ABSTRACT The cannabinoid system is being researched as a potential pharmaceutical target for a multitude of disorders. The present...
Differential Behavior of Conformational Dynamics in Active and Inactive States of Cannabinoid Receptor 1 Revealed by Microsecond-Level Molecular Dynamics Simulation
bioRxiv [Preprint]. 2024 Apr 20:2024.04.17.589939. doi: 10.1101/2024.04.17.589939. ABSTRACT The cannabinoid receptor CB1 is a G protein-coupled receptor that regulates critical physiological processes including pain, appetite,...
Cannabinoid type-1 receptor signaling in dopaminergic Engrailed-1 expressing neurons modulates motivation and depressive-like behavior
Front Mol Neurosci. 2024 Apr 4;17:1379889. doi: 10.3389/fnmol.2024.1379889. eCollection 2024. ABSTRACT The endocannabinoid system comprises highly versatile signaling functions within the nervous system. It is...
Discriminative stimulus properties of Cannabis sativa terpenes in rats
Behav Pharmacol. 2024 Apr 25. doi: 10.1097/FBP.0000000000000772. Online ahead of print. ABSTRACT Cannabis is a pharmacologically complex plant consisting of hundreds of potentially active compounds....