Curcumin-Attenuated TREM-1/DAP12/NLRP3/Caspase-1/IL1B, TLR4/NF-κB Pathways, and Tau Hyperphosphorylation Induced by 1,2-Diacetyl Benzene: An in Vitro and in Silico Study
Neurotox Res. 2022 Jul 4. doi: 10.1007/s12640-022-00535-1. Online ahead of print. ABSTRACT We aimed to evaluate the effects of 1,2-diacetylbenzene (DAB) and curcumin on neuroinflammation...
The Effects of Nano-Curcumin Supplementation on Leptin and Adiponectin in Migraine Patients: A Double-Blind Clinical Trial Study from Gene Expression to Clinical Symptoms
Endocr Metab Immune Disord Drug Targets. 2022 Jul 1. doi: 10.2174/1871530322666220701100817. Online ahead of print. ABSTRACT BACKGROUND: Migraine is a disabling neurogenic disorder characterized by...
Review on the Therapeutic Potential of Curcumin and its Derivatives on Glioma Biology
Neurochem Res. 2022 Jul 5. doi: 10.1007/s11064-022-03666-1. Online ahead of print. ABSTRACT Gliomas are common and aggressive brain tumors that carry a poor prognosis. The...
Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: A review of molecular pathways
Phytother Res. 2022 Jul 4. doi: 10.1002/ptr.7522. Online ahead of print. ABSTRACT Curcumin, isolated from turmeric (Curcuma longa L.) is one of the broadly studied...
Effect of Curcuma longa on glycemia, neuropathic sensation and advanced glycation end product in diabetic patients
Pak J Pharm Sci. 2022 May;35(3(Special)):873-878. ABSTRACT Diabetes is a chronic disorder affecting a large number of people throughout the world. According to the American...
Modulation of matrix metalloproteases by ciliary neurotrophic factor in human placental development
Cell Tissue Res. 2022 Jul 7. doi: 10.1007/s00441-022-03658-1. Online ahead of print. ABSTRACT Ciliary neurotrophic factor (CNTF) is a pleiotropic cytokine that signals through a...
Curcumin as a Promising Neuroprotective Agent for the Treatment of Spinal Cord Injury: A Review of the Literature
Neurospine. 2022 Jun;19(2):249-261. doi: 10.14245/ns.2244148.074. Epub 2022 Jun 30. ABSTRACT Curcumin is a polyphenolic chemical derived from the rhizomes of Curcuma longa. It has been...
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain
CNS Neurol Disord Drug Targets. 2022 Jul 7. doi: 10.2174/1871527321666220707091435. Online ahead of print. ABSTRACT BACKGROUND: Alzheimer’s disease (AD) is one of the most common...
Regulation of Gene Expression through Food-Curcumin as a Sirtuin Activity Modulator
Plants (Basel). 2022 Jun 30;11(13):1741. doi: 10.3390/plants11131741. ABSTRACT The sirtuin family comprises NAD+-dependent protein lysine deacylases, mammalian sirtuins being either nuclear (SIRT1, SIRT2, SIRT6, and...
Curcumin reduces blood-nerve barrier abnormalities and cytotoxicity to endothelial cells and pericytes induced by cisplatin
Folia Morphol (Warsz). 2022 Jul 12. doi: 10.5603/FM.a2022.0065. Online ahead of print. ABSTRACT Cisplatin is a platinum-based antineoplastic agent used to treat cancers of solid...
Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer’s disease via NLRP3-inhibition
J Nanobiotechnology. 2022 Jul 14;20(1):322. doi: 10.1186/s12951-022-01524-4. ABSTRACT BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disorder without effective therapy and lack diagnosis strategy...
An anti-inflammatory and neuroprotective biomimetic nanoplatform for repairing spinal cord injury
Bioact Mater. 2022 Jun 2;18:569-582. doi: 10.1016/j.bioactmat.2022.05.026. eCollection 2022 Dec. ABSTRACT Spinal cord regeneration after a spinal cord injury (SCI) remains a difficult challenge due...
Non-micronized and micronized curcumin do not prevent the behavioral and neurochemical effects induced by acute stress in zebrafish
Pharmacol Rep. 2022 Jul 19. doi: 10.1007/s43440-022-00389-6. Online ahead of print. ABSTRACT BACKGROUND: Curcumin, a polyphenol extracted from the rhizome of Curcuma longa L. (Zingiberaceae),...
Visual analysis on regulation of necroptosis with Chinese medicine based on VOSviewer and CiteSpace knowledge graphs
Zhongguo Zhong Yao Za Zhi. 2022 Jul;47(14):3933-3942. doi: 10.19540/j.cnki.cjcmm.20220428.501. ABSTRACT The study was conducted by searching the literature related to the regulation of necroptosis with...
Prevention of Bortezomib-Induced Peripheral Neuropathy in Newly Multiple Myeloma Patients Using Nervonic Acid, Curcuma Rizoma, and L-Arginine Compound: A Pilot Study
Integr Cancer Ther. 2022 Jan-Dec;21:15347354221114142. doi: 10.1177/15347354221114142. ABSTRACT INTRODUCTION: This is a phase II pilot study to evaluate the efficacy of a nutraceutical compound composed...