Determination of eight cannabinoids in foods with enhanced matrix removal-lipid adsorbent by ultra performance liquid chromatography-tandem mass spectrometry
Se Pu. 2023 May 8;41(5):426-433. doi: 10.3724/SP.J.1123.2022.08010. ABSTRACT A novel method was developed for the simultaneous determination of eight cannabinoids in six types of food...
Transfer of cannabinoids into the milk of dairy cows fed with industrial hemp could lead to Δ9-THC exposure that exceeds acute reference dose
Nat Food. 2022 Nov;3(11):921-932. doi: 10.1038/s43016-022-00623-7. Epub 2022 Nov 14. ABSTRACT The industrial hemp sector is growing and, in recent years, has launched many novel...
Repositioning Cannabinoids and Terpenes as Novel EGFR-TKIs Candidates for Targeted Therapy Against Cancer: A virtual screening model using CADD and biophysical simulations
Heliyon. 2023 Apr 17;9(4):e15545. doi: 10.1016/j.heliyon.2023.e15545. eCollection 2023 Apr. ABSTRACT This study examines the potential of Cannabis sativa L. plants to be repurposed as therapeutic...
THC in breath aerosols collected with an impaction filter device before and after legal-market product inhalation-a pilot study
J Breath Res. 2023 May 22;17(3):037103. doi: 10.1088/1752-7163/acd410. ABSTRACT An accurate cannabis breathalyzer based on quantitation of the psychoactive cannabinoid Δ9-tetrahydrocannabinol (THC) could be an...
Evaluation of Cytochrome P450-Mediated Cannabinoid-Drug Interactions in Healthy Adult Participants
Clin Pharmacol Ther. 2023 Jun 14. doi: 10.1002/cpt.2973. Online ahead of print. ABSTRACT Understanding cannabis-drug interactions is critical given regulatory changes that have increased access...
Usefulness of nabilone as an antiemetic in persistent vomiting due to refractory gastrointestinal disorders
Rev Esp Enferm Dig. 2023 Jun 14. doi: 10.17235/reed.2023.9719/2023. Online ahead of print. ABSTRACT Nabilone, a synthetic analogue of delta-9-Tetrahydrocannabinol, is an agonist of cannabinoid...
Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry
Psychopharmacology (Berl). 2023 Jun 14. doi: 10.1007/s00213-023-06399-3. Online ahead of print. ABSTRACT RATIONALE: Cannabis-based medicinal products (CBMPs) have been identified as novel therapeutics for generalised...
Evaluation of Cytochrome P450-Mediated Cannabinoid-Drug Interactions in Healthy Adult Participants
Clin Pharmacol Ther. 2023 Jun 14. doi: 10.1002/cpt.2973. Online ahead of print. ABSTRACT Understanding cannabis-drug interactions is critical given regulatory changes that have increased access...
Dietary Cholesterol Supplementation Inhibits the Steroid Biosynthesis but Does Not Affect the Cholesterol Transport in Two Marine Teleosts: A Hepatic Transcriptome Study
Aquac Nutr. 2023 Jun 5;2023:2308669. doi: 10.1155/2023/2308669. eCollection 2023. ABSTRACT Cholesterol has been used as additive in fish feeds due to the reduced use of...
Cannabinoid receptor type 1 regulates sequential stages of migration and morphogenesis of neural crest cells and derivatives in chicken and frog embryos
J Morphol. 2023 Jul;284(7):e21606. doi: 10.1002/jmor.21606. ABSTRACT The main cannabinoid receptor CB1R first shows expression during early neurula stage in chicken (Gallus gallus) embryos, and...
Toxicological safety assessment of HempChoice® hemp oil extract; a proprietary extract consisting of a high concentration of cannabidiol (CBD) in addition to other phytocannabinoids and terpenes derived from CannabissativaL
Heliyon. 2023 Jun 2;9(6):e16913. doi: 10.1016/j.heliyon.2023.e16913. eCollection 2023 Jun. ABSTRACT HempChoice® Hemp Oil Extract (Geocann, LLC) is an extract of the aerial parts of hemp...
A collection of cannabinoid-related negative findings from autaptic hippocampal neurons
Sci Rep. 2023 Jun 13;13(1):9610. doi: 10.1038/s41598-023-36710-3. ABSTRACT Autaptic hippocampal neurons are an architecturally simple model of neurotransmission that express several forms of cannabinoid signaling....
Cognitive dysfunctions and impaired neuroplasticity following repeated exposure to the synthetic cannabinoid JWH-018 in male mice
Br J Pharmacol. 2023 Jun 13. doi: 10.1111/bph.16164. Online ahead of print. ABSTRACT BACKGROUND AND PURPOSE: Psychotic disorders have been reported in long-term users of...
Recreational cannabis: Profile of cannabinoids present in marijuana samples supplied by the consuming population
Salud Colect. 2023 Mar 30;19:e4385. doi: 10.18294/sc.2023.4385. ABSTRACT As cannabis/marijuana is one of the most consumed psychoactive substances in the world, knowing the composition and...
Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals
Psychol Med. 2023 Jun 13:1-12. doi: 10.1017/S0033291723001642. Online ahead of print. ABSTRACT BACKGROUND: Several hypotheses may explain the association between substance use, posttraumatic stress disorder...