DoE-assisted development and validation of a stability-indicating HPLC-DAD method for simultaneous determination of five cannabinoids in Cannabis sativa L. based on analytical quality by design (AQbD) concept
Phytochem Anal. 2022 Oct;33(7):999-1017. doi: 10.1002/pca.3154. Epub 2022 Jun 22. ABSTRACT INTRODUCTION: Medical uses of Cannabis sativa L. have gained interest in recent decades, which...
Simulated microgravity contributed to modification of callogenesis performance and secondary metabolite production in CannabisIndica
Plant Physiol Biochem. 2022 Sep 1;186:157-168. doi: 10.1016/j.plaphy.2022.07.012. Epub 2022 Jul 14. ABSTRACT In vitro plant culture paves the way for meeting the industrial demand...
A polarized supercell produces specialized metabolites in cannabis trichomes
Curr Biol. 2022 Sep 26;32(18):4040-4047.e4. doi: 10.1016/j.cub.2022.07.014. Epub 2022 Aug 1. ABSTRACT For centuries, humans have cultivated cannabis for the pharmacological properties that result from...
Cis-Δ9-tetrahydrocannabinolic acid occurrence in Cannabis sativa L
J Pharm Biomed Anal. 2022 Sep 20;219:114958. doi: 10.1016/j.jpba.2022.114958. Epub 2022 Jul 22. ABSTRACT Cannabidiolic acid (CBDA) and trans-Δ9-tetrahydrocannabinolic acid (trans-Δ9-THCA) are known to be...
Rapid quantification of cannabinoids in beef tissues and bodily fluids using direct-delivery electrospray ionization mass spectrometry
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2022 Oct;39(10):1705-1717. doi: 10.1080/19440049.2022.2107711. Epub 2022 Aug 8. ABSTRACT Hempseed cake is a byproduct...
Quantification of Cannabis in Infused Consumer Products and Their Residues on Skin
ACS Pharmacol Transl Sci. 2022 Jul 18;5(8):642-651. doi: 10.1021/acsptsci.2c00077. eCollection 2022 Aug 12. ABSTRACT Cannabis consumer products are a $4.6 billion industry in the U.S....
Modulation of type 1 cannabinoid receptor activity by cannabinoid by-products from Cannabis sativa and non-cannabis phytomolecules
Front Pharmacol. 2022 Aug 26;13:956030. doi: 10.3389/fphar.2022.956030. eCollection 2022. ABSTRACT Cannabis sativa contains more than 120 cannabinoids and 400 terpene compounds (i.e., phytomolecules) present in...
Application of experimental design in HPLC method optimisation for the simultaneous determination of multiple bioactive cannabinoids
J Pharm Biomed Anal. 2022 Nov 30;221:115037. doi: 10.1016/j.jpba.2022.115037. Epub 2022 Sep 9. ABSTRACT The scientific interest in Cannabis sativa L. analysis has been rapidly...
Natural vs. artificial cannabinoid oils: the comparison of their antioxidant activities
Eur Food Res Technol. 2023;249(2):359-366. doi: 10.1007/s00217-022-04121-9. Epub 2022 Sep 22. ABSTRACT In the wide range of products containing hemp ingredients, cannabinoid oils are the...
Semiquantitative Screening of THC Analogues by Silica Gel TLC with an Ag(I) Retention Zone and Chromogenic Smartphone Detection
Anal Chem. 2022 Oct 11;94(40):13710-13718. doi: 10.1021/acs.analchem.2c01627. Epub 2022 Sep 30. ABSTRACT With the ever-evolving cannabis industry, low-cost and high-throughput analytical methods for cannabinoids are...
Medical cannabis dimethyl ether, ethanol and butane extracts inhibit the in vitro growth of bacteria and dermatophytes causing common skin diseases
Front Microbiol. 2022 Sep 20;13:953092. doi: 10.3389/fmicb.2022.953092. eCollection 2022. ABSTRACT Cannabis preparations are gaining popularity among patients with various skin diseases. Due to the lack...
Development and Validation of a GC-FID Method for the Quantitation of 20 Different Acidic and Neutral Cannabinoids
Planta Med. 2023 May;89(6):683-696. doi: 10.1055/a-1962-8165. Epub 2022 Oct 18. ABSTRACT For decades, Cannabis sativa had been illegal to sell or consume around the world,...
Supercritical fluids in analysis of cannabinoids in various Cannabis products
Anal Chim Acta. 2022 Nov 1;1232:340452. doi: 10.1016/j.aca.2022.340452. Epub 2022 Sep 30. ABSTRACT We developed a fast, selective, and sensitive method for the determination of...
Medical Cannabis Use and Inflammatory Cytokines and Chemokines Among Adult Chronic Pain Patients
Cannabis Cannabinoid Res. 2022 Nov 4. doi: 10.1089/can.2022.0143. Online ahead of print. ABSTRACT Background: Utilizing cannabis as a therapeutic option for chronic pain (CP) has...
Nutrient digestibility, rumen parameters, and (cannabinoid) residues in sheep fed a pelleted diet containing green hemp (Cannabis sativa L.) biomass
Transl Anim Sci. 2022 Oct 26;6(4):txac141. doi: 10.1093/tas/txac141. eCollection 2022 Oct. ABSTRACT The feeding value for ruminants of green hemp biomass, from the low Δ9-tetrahydrocannabinol...