Sequential steps of the incorporation of bioactive plant extracts from wild Italian Plantago coronopus L. and Cichorium intybus L. leaves in fresh egg pasta
Food Chem. 2022 Aug 1;384:132462. doi: 10.1016/j.foodchem.2022.132462. Epub 2022 Feb 16. ABSTRACT The application of bioactive extracts from Cichorium intybus L. and Plantago coronopus L....
Synergistic effects of Nepeta menthoides and Melissa officinalis aqueous extracts on reserpine-induced depressive-like behaviors in mice
Phytother Res. 2022 Jun;36(6):2481-2494. doi: 10.1002/ptr.7457. Epub 2022 Apr 26. ABSTRACT Nepeta menthoides Boiss. & Buhse and Melissa officinalis are extensively used in Persian medicine...
Polyphenols and Maillard Reaction Products in Dried Prunus spinosa Fruits: Quality Aspects and Contribution to Anti-Inflammatory and Antioxidant Activity in Human Immune Cells Ex Vivo
Molecules. 2022 May 20;27(10):3302. doi: 10.3390/molecules27103302. ABSTRACT Dried Prunus spinosa fruits (sloes) are folk phytotherapeutics applied to treat chronic inflammatory disorders. However, their pharmacological potential,...
Development of Synergy-Based Combination of Methanolic Extract of Andrographis paniculata and Berberis aristata Against E. coli and S. aureus
Curr Microbiol. 2022 Jun 15;79(8):223. doi: 10.1007/s00284-022-02911-8. ABSTRACT This study evaluates the antibacterial activity and phytochemical characterizations of Andrographis paniculata extract (APE) and Berberis aristata...
Isolated compounds from Dracaena angustifolia Roxb and acarbose synergistically/additively inhibit α-glucosidase and α-amylase: an in vitro study
BMC Complement Med Ther. 2022 Jul 2;22(1):177. doi: 10.1186/s12906-022-03649-3. ABSTRACT BACKGROUND: As a traditional herbal medicine, Dracaena angustifolia Roxb has been used as an anti-inflammatory...
A proof of concept ‘phase zero’ study of neurodevelopment using brain organoid models with Vis/near-infrared spectroscopy and electrophysiology
Sci Rep. 2020 Dec 2;10(1):20987. doi: 10.1038/s41598-020-77929-8. ABSTRACT Homeostatic control of neuronal excitability by modulation of synaptic inhibition (I) and excitation (E) of the principal...
Association of gut-related metabolites with outcome in acute heart failure
Am Heart J. 2021 Apr;234:71-80. doi: 10.1016/j.ahj.2021.01.006. Epub 2021 Jan 14. ABSTRACT BACKGROUND: Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF)...
Metabolomics of Cerebrospinal Fluid from Healthy Subjects Reveal Metabolites Associated with Ageing
Metabolites. 2021 Feb 23;11(2):126. doi: 10.3390/metabo11020126. ABSTRACT To increase our understanding of age-related diseases affecting the central nervous system (CNS) it is important to understand...
Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS) -induced neuroinflammation by targeting TLR4/NFκB, autophagy, inflammation and oxidative stress
Metab Brain Dis. 2021 Aug;36(6):1391-1401. doi: 10.1007/s11011-021-00715-6. Epub 2021 Mar 12. ABSTRACT Acetyl-L-carnitine has been shown to exert neuroprotection against neurodegenerative diseases. The present study...
Effect of acetyl-L-carnitine on hypersensitivity in acute recurrent caerulein-induced pancreatitis and microglial activation along the brain’s pain circuitry
World J Gastroenterol. 2021 Mar 7;27(9):794-814. doi: 10.3748/wjg.v27.i9.794. ABSTRACT BACKGROUND: Acute pancreatitis (AP) and recurring AP are serious health care problems causing excruciating pain and...
Correction to: Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS) -induced neuroinflammation by targeting TLR4/NFκB, autophagy, inflammation and oxidative stress
Metab Brain Dis. 2021 Aug;36(6):1403. doi: 10.1007/s11011-021-00721-8. NO ABSTRACT PMID:33788081 | DOI:10.1007/s11011-021-00721-8...
Long-Chain Acylcarnitines and Monounsaturated Fatty Acids Discriminate Heart Failure Patients According to Pulmonary Hypertension Status
Metabolites. 2021 Mar 26;11(4):196. doi: 10.3390/metabo11040196. ABSTRACT Defects in fatty acid (FA) utilization have been well described in group 1 pulmonary hypertension (PH) and in...
Combination photobiomodulation/N-acetyl-L-cysteine treatment appears to mitigate hair cell loss associated with noise-induced hearing loss in rats
Lasers Med Sci. 2021 Dec;36(9):1941-1947. doi: 10.1007/s10103-021-03304-2. Epub 2021 Apr 6. ABSTRACT Sensorineural hearing loss is an intractable disease. Acoustic overstimulation creates hearing loss; many...
The Alteration of L-Carnitine Transport and Pretreatment Effect under Glutamate Cytotoxicity on Motor Neuron-Like NSC-34 Lines
Pharmaceutics. 2021 Apr 14;13(4):551. doi: 10.3390/pharmaceutics13040551. ABSTRACT L-Carnitine (LC) is essential for transporting fatty acids to the mitochondria for β-oxidation. This study was performed to...
Analgesic and Antidepressant Effects of the Clinical Glutamate Modulators Acetyl-L-Carnitine and Ketamine
Front Neurosci. 2021 May 11;15:584649. doi: 10.3389/fnins.2021.584649. eCollection 2021. ABSTRACT Pain and depression are leading causes of disability and of profound social and economic burden....