A systematic review of minor phytocannabinoids with promising neuroprotective potential
Br J Pharmacol. 2020 Oct;177(19):4330-4352. doi: 10.1111/bph.15185. Epub 2020 Sep 1. ABSTRACT Embase and PubMed were systematically searched for articles addressing the neuroprotective properties of...
Anticancer Effect of New Cannabinoids Derived from Tetrahydrocannabinolic Acid on PANC-1 and AsPC-1 Human Pancreas Tumor Cells
J Pancreat Cancer. 2020 Jun 9;6(1):40-44. doi: 10.1089/pancan.2020.0003. eCollection 2020. ABSTRACT Purpose: New tetrahydrocannabinolic acid (THCA) derivatives ALAM027 and ALAM108 were proposed for the treatment...
Plasma concentrations of eleven cannabinoids in cattle following oral administration of industrial hemp (Cannabis sativa)
Sci Rep. 2020 Jul 29;10(1):12753. doi: 10.1038/s41598-020-69768-4. ABSTRACT Cannabinoid production for medicinal purposes has renewed interest in utilizing byproducts of industrial hemp (IH) as a...
Serum cannabidiol, tetrahydrocannabinol (THC), and their native acid derivatives after transdermal application of a low-THC Cannabis sativa extract in beagles
J Vet Pharmacol Ther. 2020 Sep;43(5):508-511. doi: 10.1111/jvp.12896. Epub 2020 Jul 31. ABSTRACT Cannabinoids hold promise for treating health problems related to inflammation and chronic...
A Cup of Hemp Coffee by Moka Pot from Southern Italy: An UHPLC-HRMS Investigation
Foods. 2020 Aug 14;9(8):1123. doi: 10.3390/foods9081123. ABSTRACT After a long period defined by prohibition of hemp production, this crop has been recently re-evaluated in various...
Quantitative determination and validation of 17 cannabinoids in cannabis and hemp using liquid chromatography-tandem mass spectrometry
Anal Bioanal Chem. 2020 Nov;412(27):7381-7393. doi: 10.1007/s00216-020-02862-8. Epub 2020 Aug 24. ABSTRACT The increase in production of cannabis for medical and recreational purposes in recent...
Aquaponic and Hydroponic Solutions Modulate NaCl-Induced Stress in Drug-Type Cannabis sativa L
Front Plant Sci. 2020 Aug 5;11:1169. doi: 10.3389/fpls.2020.01169. eCollection 2020. ABSTRACT The effects of salt-induced stress in drug-type Cannabis sativa L. (C. sativa), a crop...
Comment on Lachenmeier et al (2020) “Are side effects of cannabidiol (CBD) products caused by tetrahydrocannabinol (THC) contamination?”: disputation on various points in the publication
F1000Res. 2020 Aug 4;9:900. doi: 10.12688/f1000research.25354.1. eCollection 2020. ABSTRACT This Correspondence article is a counterstatement to a Brief Report published by Lachenmeier and co-workers on...
Combination of UV and MS/MS detection for the LC analysis of cannabidiol-rich products
Talanta. 2020 Nov 1;219:121250. doi: 10.1016/j.talanta.2020.121250. Epub 2020 Jun 17. ABSTRACT Cannabidiol (CBD), a major non-psychoactive cannabinoid, has received a lot of attention due to...
Cannabis Chemovar Nomenclature Misrepresents Chemical and Genetic Diversity; Survey of Variations in Chemical Profiles and Genetic Markers in Nevada Medical Cannabis Samples
Cannabis Cannabinoid Res. 2020 Sep 2;5(3):215-230. doi: 10.1089/can.2018.0063. eCollection 2020. ABSTRACT Introduction: Medical cannabis patients receive clinical benefits from the secondary metabolites of the plant,...
Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae
J Nat Prod. 2020 Oct 23;83(10):2877-2893. doi: 10.1021/acs.jnatprod.0c00241. Epub 2020 Oct 1. ABSTRACT Phytocannabinoids are a group of plant-derived metabolites that display a wide range...
Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast
Appl Microbiol Biotechnol. 2020 Nov;104(22):9551-9563. doi: 10.1007/s00253-020-10798-3. Epub 2020 Oct 12. ABSTRACT Heterologous biosynthesis of tetrahydrocannabinolic acid (THCA) in yeast is a biotechnological process in...
Pharmacokinetics of Cannabidiol, Cannabidiolic Acid, Δ9-Tetrahydrocannabinol, Tetrahydrocannabinolic Acid and Related Metabolites in Canine Serum After Dosing With Three Oral Forms of Hemp Extract
Front Vet Sci. 2020 Sep 4;7:505. doi: 10.3389/fvets.2020.00505. eCollection 2020. ABSTRACT Cannabidiol (CBD)-rich hemp extract use is increasing in veterinary medicine with little examination of...
Cannabis sativa extracts protect LDL from Cu2+-mediated oxidation
J Cannabis Res. 2020;2:37. doi: 10.1186/s42238-020-00042-0. Epub 2020 Oct 15. ABSTRACT BACKGROUND: Multiple therapeutic properties have been attributed to Cannabis sativa. However, further research is...
Disposition of cannabinoids and their metabolites in serum, oral fluid, sweat patch and urine from healthy individuals treated with pharmaceutical preparations of medical cannabis
Phytother Res. 2021 Mar;35(3):1646-1657. doi: 10.1002/ptr.6931. Epub 2020 Nov 6. ABSTRACT Recently, several countries authorized the use of cannabis flowering tops (dried inflorescences) with a...