Examining the hepatotoxic potential of cannabidiol, cannabidiol-containing hemp extract, and cannabinol at consumer-relevant exposure concentrations in primary human hepatocytes
J Appl Toxicol. 2024 Jun 26. doi: 10.1002/jat.4646. Online ahead of print. ABSTRACT Hemp extracts and consumer products containing cannabidiol (CBD) and/or other phytocannabinoids derived...
Effects of Orange Peel Extract on Laccase Activity and Gene Expression in Trametes versicolor
J Fungi (Basel). 2024 May 22;10(6):370. doi: 10.3390/jof10060370. ABSTRACT The genome of Trametes versicolor encodes multiple laccase isozymes, the expression of which is responsive to...
Cannabinerol Prevents Endoplasmic Reticulum and Mitochondria Dysfunctions in an In Vitro Model of Alzheimer’s Disease: A Network-Based Transcriptomic Analysis
Cells. 2024 Jun 10;13(12):1012. doi: 10.3390/cells13121012. ABSTRACT Neurodegenerative disorders are affecting millions of people worldwide, impacting the healthcare system of our society. Among them, Alzheimer’s...
Cannabigerol-A useful agent restoring the muscular phospholipids milieu in obese and insulin-resistant Wistar rats?
Front Mol Biosci. 2024 Jun 11;11:1401558. doi: 10.3389/fmolb.2024.1401558. eCollection 2024. ABSTRACT Numerous strategies have been proposed to minimize obesity-associated health effects, among which phytocannabinoids appear...
Artificial Manganese Metalloenzymes with Laccase-like Activity: Design, Synthesis, and Characterization
ACS Appl Bio Mater. 2024 Jun 25. doi: 10.1021/acsabm.4c00571. Online ahead of print. ABSTRACT Laccase is an oxidase of great industrial interest due to its...
Chemical compounds, anti-tumor and anti-neuropathic pain effect of hemp essential oil in vivo
Fitoterapia. 2024 Jun 22:106092. doi: 10.1016/j.fitote.2024.106092. Online ahead of print. ABSTRACT Hemp (Cannabis sativa L.), an annual dioecious plant, has shown extensive application in the...
The effects of a brand-specific, hemp-derived cannabidiol product on physiological, biochemical, and psychometric outcomes in healthy adults: a double-blind, randomized clinical trial
J Int Soc Sports Nutr. 2024 Dec;21(1):2370430. doi: 10.1080/15502783.2024.2370430. Epub 2024 Jun 21. ABSTRACT BACKGROUND: Cannabidiol (CBD) is a non-psychoactive phyto-cannabinoid derived from the Cannabis...
Isolation, Identification, Phytochemical Characterization, and In Vitro Anti-Inflammatory Property of an Endophytic Trametes versicolor CL-1 Isolated from Rosa roxburghii
Chem Biodivers. 2024 Jun 20:e202400873. doi: 10.1002/cbdv.202400873. Online ahead of print. ABSTRACT This study explores the anti-inflammatory potential of an endophytic fungus, Trametes versicolor CL-1,...
Decay and Termite Resistance of Wood Modified by High-Temperature Vapour-Phase Acetylation (HTVPA), a Simultaneous Acetylation and Heat Treatment Modification Process
Polymers (Basel). 2024 Jun 5;16(11):1601. doi: 10.3390/polym16111601. ABSTRACT High-temperature vapour-phase acetylation (HTVPA) is a simultaneous acetylation and heat treatment process for wood modification. This study...
Comparison of the Effects of Essential Oils from Cannabis sativa and Cannabis indica on Selected Bacteria, Rumen Fermentation, and Methane Production-In Vitro Study
Int J Mol Sci. 2024 May 28;25(11):5861. doi: 10.3390/ijms25115861. ABSTRACT This study aimed to evaluate the effects of essential oils (EOs) extracted from Cannabis sativa...
Modulation of Redox and Inflammatory Signaling in Human Skin Cells Using Phytocannabinoids Applied after UVA Irradiation: In Vitro Studies
Cells. 2024 Jun 3;13(11):965. doi: 10.3390/cells13110965. ABSTRACT UVA exposure disturbs the metabolism of skin cells, often inducing oxidative stress and inflammation. Therefore, there is a...
The novel anti-fibrillary effects of volatile compounds α-asarone and β-caryophyllene on tau protein: Towards promising therapeutic agents for Alzheimer’s disease
Int J Biol Macromol. 2024 Jun;271(Pt 2):132401. doi: 10.1016/j.ijbiomac.2024.132401. Epub 2024 May 17. ABSTRACT The abnormal deposition of tau protein is one of the critical...
Evaluation of Aromatic Characteristics and Potential Applications of Hemerocallis L. Based on the Analytic Hierarchy Process
Molecules. 2024 Jun 6;29(11):2712. doi: 10.3390/molecules29112712. ABSTRACT Hemerocallis L. possesses abundant germplasm resources and holds significant value in terms of ornamental, edible, and medicinal aspects....
Minor Cannabinoids as Inhibitors of Skin Inflammation: Chemical Synthesis and Biological Evaluation
J Nat Prod. 2024 Jun 18. doi: 10.1021/acs.jnatprod.4c00212. Online ahead of print. ABSTRACT Despite millennia of therapeutic plant use, deliberate exploitation of Cannabis’s diverse biomedical...
Airlift bioreactor-based strategies for prolonged semi-continuous cultivation of edible Agaricomycetes
Appl Microbiol Biotechnol. 2024 Jun 18;108(1):377. doi: 10.1007/s00253-024-13220-4. ABSTRACT Submerged cultivation of edible filamentous fungi (Agaricomycetes) in bioreactors enables maximum mass transfer of nutrients and...