The State of Synthetic Cannabinoid Medications for the Treatment of Pain
CNS Drugs. 2024 Jul 1. doi: 10.1007/s40263-024-01098-9. Online ahead of print. ABSTRACT Synthetic cannabinoids are compounds made in the laboratory to structurally and functionally mimic...
Thermally induced changes in the profiles of phytocannabinoids and other bioactive compounds in Cannabis sativa L. inflorescences
Food Res Int. 2024 Aug;190:114487. doi: 10.1016/j.foodres.2024.114487. Epub 2024 May 27. ABSTRACT Phytocannabinoids occurring in Cannabis Sativa L. are unique secondary metabolites possessing interesting pharmacological...
A new HPLC method with multiple detection systems for impurity analysis and discrimination of natural versus synthetic cannabidiol
Anal Bioanal Chem. 2024 Jun 28. doi: 10.1007/s00216-024-05396-5. Online ahead of print. ABSTRACT Cannabidiol (CBD) is the main non-psychoactive phytocannabinoid derived from Cannabis sativa L....
Development and validation of a quantitative method for the analysis of delta-9-tetrahydrocannabinol (delta-9-THC), delta-8-tetrahydrocannabinol (delta-8-THC), delta-9-tetrahydrocannabinolic acid (THCA), and cannabidiol (CBD) in botanicals, edibles, liquids, oils, waxes, and bath products by gas chromatography mass spectrometry (GC/MS)
J Forensic Sci. 2024 Jun 28. doi: 10.1111/1556-4029.15574. Online ahead of print. ABSTRACT A quantitative gas chromatography mass spectrometry (GC/MS) method was developed for delta-9-tetrahydrocannabinol...
Single and Combined Effects of Cannabigerol (CBG) and Cannabidiol (CBD) in Mouse Models of Oxaliplatin-Associated Mechanical Sensitivity, Opioid Antinociception, and Naloxone-Precipitated Opioid Withdrawal
Biomedicines. 2024 May 22;12(6):1145. doi: 10.3390/biomedicines12061145. ABSTRACT Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most prevalent and dose-limiting complications in chemotherapy patients, with estimates...
Cannabinoids’ Role in Modulating Central and Peripheral Immunity in Neurodegenerative Diseases
Int J Mol Sci. 2024 Jun 10;25(12):6402. doi: 10.3390/ijms25126402. ABSTRACT Cannabinoids (the endocannabinoids, the synthetic cannabinoids, and the phytocannabinoids) are well known for their various...
Cannabidiol Protects against the Reinstatement of Oxycodone-Induced Conditioned Place Preference in Adolescent Male but Not Female Rats: The Role of MOR and CB1R
Int J Mol Sci. 2024 Jun 17;25(12):6651. doi: 10.3390/ijms25126651. ABSTRACT Cannabidiol (CBD), a phytocannabinoid, appeared to satisfy several criteria for a safe approach to preventing...
Effects of Cannabinoids on Intestinal Motility, Barrier Permeability, and Therapeutic Potential in Gastrointestinal Diseases
Int J Mol Sci. 2024 Jun 18;25(12):6682. doi: 10.3390/ijms25126682. ABSTRACT Cannabinoids and their receptors play a significant role in the regulation of gastrointestinal (GIT) peristalsis...
Potential of CBD Acting on Cannabinoid Receptors CB1 and CB2 in Ischemic Stroke
Int J Mol Sci. 2024 Jun 18;25(12):6708. doi: 10.3390/ijms25126708. ABSTRACT Stroke is one of the leading causes of death. It not only affects adult people...
Clinical and Family Implications of Cannabidiol (CBD)-Dominant Full-Spectrum Phytocannabinoid Extract in Children and Adolescents with Moderate to Severe Non-Syndromic Autism Spectrum Disorder (ASD): An Observational Study on Neurobehavioral Management
Pharmaceuticals (Basel). 2024 May 27;17(6):686. doi: 10.3390/ph17060686. ABSTRACT Autism Spectrum Disorder (ASD) encompasses a wide range of neurodevelopmental conditions characterized by deficits in social interaction,...
Cannabinoids: Potential for Modulation and Enhancement When Combined with Vitamin B12 in Case of Neurodegenerative Disorders
Pharmaceuticals (Basel). 2024 Jun 20;17(6):813. doi: 10.3390/ph17060813. ABSTRACT The enduring relationship between humanity and the cannabis plant has witnessed significant transformations, particularly with the widespread...
Development and Characterization of a Microemulsion Containing a Cannabidiol Oil and a Hydrophilic Extract from Sambucus ebulus for Topical Administration
Pharmaceutics. 2024 May 24;16(6):705. doi: 10.3390/pharmaceutics16060705. ABSTRACT Cannabidiol (CBD) is a safe and non-psychotropic phytocannabinoid with a wide range of potential therapeutic anti-inflamatory and antioxidant...
The potential neuroprotective effects of cannabinoids against paclitaxel-induced peripheral neuropathy: in vitro study on neurite outgrowth
Front Pharmacol. 2024 Jun 12;15:1395951. doi: 10.3389/fphar.2024.1395951. eCollection 2024. ABSTRACT Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a shared burden for 68.1% of oncological patients undergoing...
Improved productivity and dye removal performance of Trametes versicolor pellets using rice husk as a co-substrate
J Microbiol Methods. 2024 Jun 24:106976. doi: 10.1016/j.mimet.2024.106976. Online ahead of print. ABSTRACT Pellet production represents a critical step for several processes requiring fungal biomass,...
Therapeutic potential of cannabidiol (CBD) in anxiety disorders: A systematic review and meta-analysis
Psychiatry Res. 2024 Jun 21;339:116049. doi: 10.1016/j.psychres.2024.116049. Online ahead of print. ABSTRACT Cannabidiol (CBD), as one of the phytocannabinoids, has a wide range of therapeutic...