Gynostemma pentaphyllum for dyslipidemia: A systematic review of randomized controlled trials
Front Pharmacol. 2022 Aug 26;13:917521. doi: 10.3389/fphar.2022.917521. eCollection 2022. ABSTRACT Objective: To evaluate the lipid-lowering effect and safety of Gynostemma pentaphyllum (GP) used alone or...
Topical Administration of a Marine Oil Rich in Pro-Resolving Lipid Mediators Accelerates Wound Healing in Diabetic db/db Mice through Angiogenesis and Macrophage Polarization
Int J Mol Sci. 2022 Aug 31;23(17):9918. doi: 10.3390/ijms23179918. ABSTRACT Impaired wound healing in patients with type 2 diabetes (DM2) is characterized by chronic inflammation,...
Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update
Front Pharmacol. 2022 Apr 8;13:865376. doi: 10.3389/fphar.2022.865376. eCollection 2022. ABSTRACT Depression is a global health problem with growing prevalence rates and serious impacts on the...
Quercetin: an effective polyphenol in alleviating diabetes and diabetic complications
Crit Rev Food Sci Nutr. 2022 Apr 25:1-24. doi: 10.1080/10408398.2022.2067825. Online ahead of print. ABSTRACT Various studies, especially in recent years, have shown that quercetin...
Partial carbonization of quercetin boosts the antiviral activity against H1N1 influenza A virus
J Colloid Interface Sci. 2022 Apr 26;622:481-493. doi: 10.1016/j.jcis.2022.04.124. Online ahead of print. ABSTRACT Inflenza A viruses (IAVs) are highly transmissible and pathogenic Orthomyxoviruses, which...
[Corrigendum] Quercetin protects rat cortical neurons against traumatic brain injury
Mol Med Rep. 2022 Jul;26(1):216. doi: 10.3892/mmr.2022.12732. Epub 2022 May 11. ABSTRACT Subsequently to the publication of the above paper, an interested reader drew to...
Quercetin alleviated multi-walled carbon nanotubes-induced neurotoxicity in mice through inhibition of oxidation, inflammation, and pyroptosis
Biomed Pharmacother. 2022 May 20;151:113160. doi: 10.1016/j.biopha.2022.113160. Online ahead of print. ABSTRACT Recently, we reported that quercetin (Que) could alleviate immunotoxicity induced by pristine multi-walled...
Neuroprotective Effects of Quercetin on Ischemic Stroke: A Literature Review
Front Pharmacol. 2022 May 18;13:854249. doi: 10.3389/fphar.2022.854249. eCollection 2022. ABSTRACT Ischemic stroke (IS) is characterized by high recurrence and disability; however, its therapies are very...
Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway
Front Neurol. 2022 May 20;13:905640. doi: 10.3389/fneur.2022.905640. eCollection 2022. ABSTRACT The pathogenesis of spinal cord injury (SCI) is complex. At present, there is no effective...
Quercetin binding accelerates prion fibrillation into proteinase sensitive and loosely structured amyloids
Biomed Pharmacother. 2022 Jul;151:113177. doi: 10.1016/j.biopha.2022.113177. Epub 2022 May 27. ABSTRACT Amyloidoses are caused by the deposition of amyloid fibrils ascribed to protein misfolding. In...
Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin
Ecotoxicol Environ Saf. 2022 Jun 14;241:113772. doi: 10.1016/j.ecoenv.2022.113772. Online ahead of print. ABSTRACT Cadmium (Cd) is one of the most toxic environmental pollutants. Quercetin (Que)...
Doxorubicin-induced senescence in normal fibroblasts promotes in vitro tumour cell growth and invasiveness: the role of Quercetin in modulating these processes
Mech Ageing Dev. 2022 Jun 18:111689. doi: 10.1016/j.mad.2022.111689. Online ahead of print. ABSTRACT Ageing is a complex biological phenomenon representing the major risk factor for...
Phytochemical quercetin alleviates hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia comparable to NSAIDs
Mol Pain. 2022 Apr;18:17448069221108971. doi: 10.1177/17448069221108971. ABSTRACT Quercetin is a flavonoid that is widely found in fruits and vegetables. Quercetin inhibits cyclooxygenase-2 and modulates voltage-gated...
Pharmacological Aspects of Natural Quercetin in Rheumatoid Arthritis
Drug Des Devel Ther. 2022 Jun 29;16:2043-2053. doi: 10.2147/DDDT.S364759. eCollection 2022. ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to severe...
Neuroprotective effect of quercetin against rotenone-induced neuroinflammation and alterations in mice behavior
J Biochem Mol Toxicol. 2022 Jul 13:e23165. doi: 10.1002/jbt.23165. Online ahead of print. ABSTRACT Various studies suggested that neuroinflammation leads to the development of several...