Curcumin Suppresses Aldosterone-Induced CRP Generation in Rat Vascular Smooth Muscle Cells via Interfering with the ROS-ERK1/2 Signaling Pathway
Evid Based Complement Alternat Med. 2020 Aug 7;2020:3245653. doi: 10.1155/2020/3245653. eCollection 2020. ABSTRACT Aldosterone regulates the initiation and development of atherosclerosis which is identified as...
Curcumin inhibits the proliferation and migration of vascular smooth muscle cells by targeting the chemerin / CMKLR1 / LCN2 axis
Aging (Albany NY). 2021 May 24;13(10):13859-13875. doi: 10.18632/aging.202980. Epub 2021 May 24. ABSTRACT Atherosclerosis (AS) is a chronic progressive inflammatory disease and a leading cause...
Different Effects of Endothelial Extracellular Vesicles and LPS-Induced Endothelial Extracellular Vesicles on Vascular Smooth Muscle Cells: Role of Curcumin and Its Derivatives
Front Cardiovasc Med. 2021 May 31;8:649352. doi: 10.3389/fcvm.2021.649352. eCollection 2021. ABSTRACT Background: During the progression of atherosclerosis (AS), the vascular endothelial and smooth muscle cells...
Curcumin-mediated Photodynamic Therapy Inhibits the Phenotypic Transformation, Migration, and Foaming of Oxidized Low-density Lipoprotein-treated Vascular Smooth Muscle Cells by Promoting Autophagy
J Cardiovasc Pharmacol. 2021 Jun 2;78(2):308-318. doi: 10.1097/FJC.0000000000001069. ABSTRACT Vascular smooth muscle cells (VSMCs) are becoming a hot spot and target of atherosclerosis research. This...
Optimization of FDM 3D printing process parameters to produce haemodialysis curcumin-loaded vascular grafts
Drug Deliv Transl Res. 2021 Oct 12. doi: 10.1007/s13346-021-01078-2. Online ahead of print. ABSTRACT 3D printing has provided a new prospective in the manufacturing of...
The omega-3 and Nano-curcumin effects on vascular cell adhesion molecule (VCAM) in episodic migraine patients: a randomized clinical trial
BMC Res Notes. 2021 Jul 23;14(1):283. doi: 10.1186/s13104-021-05700-x. ABSTRACT OBJECTIVE: The purpose of this clinical trial was to examine the effect of omega-3 fatty acids...
Curcumin upregulates transforming growth factor-beta1, its receptors, and vascular endothelial growth factor expressions in an in vitro human gingival fibroblast wound healing model
BMC Oral Health. 2021 Oct 17;21(1):535. doi: 10.1186/s12903-021-01890-9. ABSTRACT BACKGROUND: Curcumin accelerates healing of oral wounds; however, the responsible mechanisms remain underexplored. Our hypothesis is...
Development of oral curcumin based on pH-responsive transmembrane peptide-cyclodextrin derivative nanoparticles for hepatoma
Carbohydr Polym. 2022 Feb 1;277:118892. doi: 10.1016/j.carbpol.2021.118892. Epub 2021 Nov 16. ABSTRACT Herein, a pH-responsive cyclodextrin derivative (R6H4-CMβCD) with cell-penetrating ability was successfully synthesized, and...
A soft Pickering emulsifier made from chitosan and peptides endows stimuli-responsiveness, bioactivity and biocompatibility to emulsion
Carbohydr Polym. 2022 Feb 1;277:118768. doi: 10.1016/j.carbpol.2021.118768. Epub 2021 Oct 18. ABSTRACT Polymeric Pickering emulsifiers may bring new insights to emulsion theory and practice due...
Enhancement of photodynamic bactericidal activity of curcumin against Pseudomonas Aeruginosa using polymyxin B
Photodiagnosis Photodyn Ther. 2021 Dec 7:102677. doi: 10.1016/j.pdpdt.2021.102677. Online ahead of print. ABSTRACT BACKGROUND: Pseudomonas aeruginosa (P. aeruginosa) is an emerging opportunistic pathogen, which can...
The Inhibitory Effect of Curcumin Derivative J147 on Melanogenesis and Melanosome Transport by Facilitating ERK-Mediated MITF Degradation
Front Pharmacol. 2021 Nov 23;12:783730. doi: 10.3389/fphar.2021.783730. eCollection 2021. ABSTRACT The therapeutic use of curcumin and chemically modified curcumin (CMC) for suppressing melanogenesis and tyrosinase...
Effects of curcumin on neurobehavior and oxidative stress in hippocampus of rats exposed to manganese
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2021 Nov 20;39(11):801-807. doi: 10.3760/cma.j.cn121094-20201126-00651. ABSTRACT Objective: To establish the animal model of subchronic manganism,...
The Multifaceted Role of Curcumin in Advanced Nanocurcumin Form in the Treatment and Management of Chronic Disorders
Molecules. 2021 Nov 24;26(23):7109. doi: 10.3390/molecules26237109. ABSTRACT Curcumin is the primary polyphenol in turmeric’s curcuminoid class. It has a wide range of therapeutic applications, such...
Design of Hybrid Polymeric-Lipid Nanoparticles Using Curcumin as a Model: Preparation, Characterization, and In Vitro Evaluation of Demethoxycurcumin and Bisdemethoxycurcumin-Loaded Nanoparticles
Polymers (Basel). 2021 Nov 30;13(23):4207. doi: 10.3390/polym13234207. ABSTRACT Polymeric lipid hybrid nanoparticles (PLHNs) are the new generation of drug delivery systems that has emerged as...
Evaluation and Characterization of Curcumin-beta-Cyclodextrin and Cyclodextrin-Based Nanosponge Inclusion Complexation
Polymers (Basel). 2021 Nov 24;13(23):4073. doi: 10.3390/polym13234073. ABSTRACT Cyclodextrin polymers and cyclodextrin-based nanosponges have been widely investigated for increasing drug bioavailability. This study examined curcumin’s...