Decreased Tissue Omega-6/Omega-3 Fatty Acid Ratio Prevents Chemotherapy-Induced Gastrointestinal Toxicity Associated with Alterations of Gut Microbiome
Int J Mol Sci. 2022 May 10;23(10):5332. doi: 10.3390/ijms23105332. ABSTRACT Gastrointestinal toxicity (GIT) is a debilitating side effect of Irinotecan (CPT-11) and limits its clinical...
Fish Oil Nanoemulsion Supplementation Attenuates Bleomycin-Induced Pulmonary Fibrosis BALB/c Mice
Nanomaterials (Basel). 2022 May 14;12(10):1683. doi: 10.3390/nano12101683. ABSTRACT Diets rich in omega-3 or -6 fatty acids will produce different profiles for cell membranes phospholipid constitutions....
Effects of Fish Oil on Biomarkers of Axonal Injury and Inflammation in American Football Players: A Placebo-Controlled Randomized Controlled Trial
Nutrients. 2022 May 20;14(10):2139. doi: 10.3390/nu14102139. ABSTRACT There are limited studies on neuroprotection from repeated subconcussive head impacts (RSHI) following docosahexaenoic acid (DHA) + eicosapentaenoic...
Effects of omega-3 fatty acid supplementation during chronic maternal hypoxia on behavioral disorders in male rat offspring: the role of Trk family and oxidative stress
Metab Brain Dis. 2022 May 27. doi: 10.1007/s11011-022-01012-6. Online ahead of print. ABSTRACT Maternal hypoxia due to a lack of blood flow and insufficient oxygen...
Manipulation of fatty acid profile and nutritional quality of Chlorella vulgaris by supplementing with citrus peel fatty acid
Sci Rep. 2022 May 17;12(1):8151. doi: 10.1038/s41598-022-12309-y. ABSTRACT Microalgae could be an excellent resource of functional and essential fatty acids. To achieve viable microalgal biomass...
Associations of baseline use of fish oil with progression of cardiometabolic multimorbidity and mortality among patients with hypertension: a prospective study of UK Biobank
Eur J Nutr. 2022 May 19. doi: 10.1007/s00394-022-02889-w. Online ahead of print. ABSTRACT PURPOSE: The role of fish oil in the prognosis of hypertensive patients...
Poultry Meat and Eggs as an Alternative Source of n-3 Long-Chain Polyunsaturated Fatty Acids for Human Nutrition
Nutrients. 2022 May 8;14(9):1969. doi: 10.3390/nu14091969. ABSTRACT The beneficial effects of n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) on human health are widely known. Humans...
Immunonutritional Targeting of Cancer via Eicosanoids
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4634. ABSTRACT Cancer causes widespread mortality via a systemic pro-inflammatory and dysregulated immune response. Immunotherapy is the front-line...
Polyunsaturated fatty acids may decrease cancer risk in rural midwestern post-menopausal women on vitamin D and calcium supplementation
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7508. ABSTRACT OBJECTIVES: Determine the extent to which fatty acid intakes at baseline are independently associated with cancer...
Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model
Cells. 2022 Apr 30;11(9):1513. doi: 10.3390/cells11091513. ABSTRACT Psoriasis is an autoimmune skin disease with an increased number of leukocytes infiltrating the dermal and epidermal compartments...
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice
Int J Mol Sci. 2022 Apr 19;23(9):4482. doi: 10.3390/ijms23094482. ABSTRACT Dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) has been used as an adjunct...
The Effects of Omega-3 Supplementation on Depression in Adults with Cardiometabolic Disease: A Systematic Review of Randomised Control Trials
Nutrients. 2022 Apr 27;14(9):1827. doi: 10.3390/nu14091827. ABSTRACT BACKGROUND: Omega-3 polyunsaturated fatty acids’ concurrent benefits for cardiometabolic and mental health are equivocal. Despite lack of evidence,...
Omega-3 Fatty Acids and Their Interaction with the Gut Microbiome in the Prevention and Amelioration of Type-2 Diabetes
Nutrients. 2022 Apr 21;14(9):1723. doi: 10.3390/nu14091723. ABSTRACT Type-2 diabetes mellitus (T2DM) is often linked with hyperglycemia, disturbed lipid profiles, inflammation, and gut dysbiosis. Omega-3 fatty...
The Impact of Omega-3 Supplements on Non-Surgical Periodontal Therapy: A Systematic Review
Nutrients. 2022 Apr 28;14(9):1838. doi: 10.3390/nu14091838. ABSTRACT AIM: This systematic review examined the additional effect of taking omega-3 supplements on periodontal therapy. METHODS: The focused...
DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the APOE4 Genotype in Rodents
Nutrients. 2022 Apr 19;14(9):1698. doi: 10.3390/nu14091698. ABSTRACT Female APOE4 carriers have a greater predisposition to developing Alzheimer’s disease (AD) compared to their male counterparts, which...