Effects of monacolin K-containing nutraceutical on cholesterol homeostasis re-establishment and CVD risk reduction in hypercholesterolemic subjects
Eur Rev Med Pharmacol Sci. 2021 Aug;25(16):5261-5267. doi: 10.26355/eurrev_202108_26546. ABSTRACT OBJECTIVE: Hypercholesterolemia is caused by cholesterol homeostasis (CH) disruption, and it contributes to cardiovascular diseases...
Skin Blood Flow Responses to Acetylcholine, Local Heating, and to 60% VO2max exercise with and without Nitric Oxide inhibition, in Boys vs. Girls
Pediatr Exerc Sci. 2021 Dec 13:1-9. doi: 10.1123/pes.2021-0121. Online ahead of print. ABSTRACT PURPOSE: To determine sex-related differences in the skin blood flow (SkBF) response...
Hexahydrocurcumin ameliorates hypertensive and vascular remodeling in L-NAME-induced rats
Biochim Biophys Acta Mol Basis Dis. 2021 Dec 6:166317. doi: 10.1016/j.bbadis.2021.166317. Online ahead of print. ABSTRACT Hexahydrocurcumin (HHC), a major metabolite of curcumin, possesses several...
Effects of L-citrulline supplementation and watermelon consumption on longer-term and postprandial vascular function and cardiometabolic risk markers: A meta-analysis of randomized controlled trials in adults
Br J Nutr. 2021 Dec 6:1-34. doi: 10.1017/S0007114521004803. Online ahead of print. ABSTRACT L-citrulline may improve non-invasive vascular function and cardiometabolic risk markers through increases...
The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseases
Life Sci. 2021 Dec 2:120193. doi: 10.1016/j.lfs.2021.120193. Online ahead of print. ABSTRACT Vitamin D is a hormone with both genomic and non-genomic actions. It exerts...
Aster ageratoides Turcz. extract attenuates Alzheimer’s disease-associated cognitive deficits and vascular dementia-associated neuronal death
Anat Cell Biol. 2020 Jun 30;53(2):216-227. doi: 10.5115/acb.20.011. ABSTRACT Dementia is the common neurodegenerative disorder affecting the elderly, with a progressive cognitive decline and memory...
Relationship between brain-derived neurotrophic factor and immune function during dietary supplement treatment of elderly with Alzheimer’s dementia
J Clin Transl Res. 2020 Jan 29;5(2):68-75. eCollection 2020 Jan 29. ABSTRACT BACKGROUND AND AIM: The objective of the present study was to investigate the...
ACR Appropriateness Criteria Dementia
J Am Coll Radiol. 2020 May;17(5S):S100-S112. doi: 10.1016/j.jacr.2020.01.040. ABSTRACT Degenerative disease of the central nervous system is a growing public health concern. The primary role...
Self-Reported Omega-3 Supplement Use Moderates the Association between Age and Exercising Cerebral Blood Flow Velocity in Older Adults
Nutrients. 2020 Mar 5;12(3):697. doi: 10.3390/nu12030697. ABSTRACT Cerebral blood flow (CBF) decreases across the lifespan, and chronic conditions such as dementia and stroke accelerate this...
Angiopoietin-1 and alphanubeta3 integrin peptide promote the therapeutic effects of L-serine in an amyotrophic lateral sclerosis/Parkinsonism dementia complex model
Aging (Albany NY). 2018 Nov 25;10(11):3507-3527. doi: 10.18632/aging.101661. ABSTRACT Amyotrophic lateral sclerosis (ALS) is an adult disorder of neurodegeneration that manifests as the destruction of...
Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats
Clin Exp Hypertens. 2019;41(8):708-716. doi: 10.1080/10641963.2018.1545846. Epub 2018 Nov 26. ABSTRACT Objective: Vascular dementia is the second leading cause of dementia, which is strongly associated...
Prolonged exposure to 1,25(OH)2D3 and high ionized calcium induces FGF-23 production in intestinal epithelium-like Caco-2 monolayer: A local negative feedback for preventing excessive calcium transport
Arch Biochem Biophys. 2018 Feb 15;640:10-16. doi: 10.1016/j.abb.2017.12.022. Epub 2018 Jan 6. ABSTRACT Overdose of oral calcium supplement and excessive intestinal calcium absorption can contribute...
An update on vinpocetine: New discoveries and clinical implications
Eur J Pharmacol. 2018 Jan 15;819:30-34. doi: 10.1016/j.ejphar.2017.11.041. Epub 2017 Nov 26. ABSTRACT Vinpocetine, a derivative of the alkaloid vincamine, has been clinically used in...
Contrasting Metabolic Insufficiency in Aging and Dementia
Aging Dis. 2021 Jul 1;12(4):1081-1096. doi: 10.14336/AD.2021.0104. eCollection 2021 Jul. ABSTRACT Metabolic insufficiency and neuronal dysfunction occur in normal aging but is exaggerated in dementia...
Safety of water extract of Cistanche tubulosa stems as a Novel food pursuant to Regulation (EU) 2015/2283
EFSA J. 2021 Jan 15;19(1):e06346. doi: 10.2903/j.efsa.2021.6346. eCollection 2021 Jan. ABSTRACT Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods...