Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9
Int J Neurosci. 2021 Feb 1:1-11. doi: 10.1080/00207454.2020.1860967. Online ahead of print. ABSTRACT Backgroud: Hyperhomocysteinemia (HHcy) is implicated in various neurovascular disorders including vascular dementia,...
Lack of direct involvement of a diazepam long-term treatment in the occurrence of irreversible cognitive impairment: a pre-clinical approach
Transl Psychiatry. 2021 Dec 3;11(1):612. doi: 10.1038/s41398-021-01718-8. ABSTRACT Several observational studies have found a link between the long-term use of benzodiazepines and dementia, which remains...
Traumatic brain injuries among veterans and the risk of incident dementia: A systematic review & meta-analysis
Age Ageing. 2021 Oct 13:afab194. doi: 10.1093/ageing/afab194. Online ahead of print. ABSTRACT BACKGROUND: Traumatic brain injuries (TBI) among military veterans are increasingly recognized as important...
Compensatory role of endogenous sulfur dioxide in nitric oxide deficiency-induced hypertension
Redox Biol. 2021 Nov 18;48:102192. doi: 10.1016/j.redox.2021.102192. Online ahead of print. ABSTRACT OBJECTIVE: This study aimed to determine the communicational pattern of gaseous signaling molecules...
Management of central hemodynamic and endothelial function disturbances in patients with myocardial infarction combined with metabolic syndrome
Pol Merkur Lekarski. 2021 Oct 22;49(293):325-328. ABSTRACT On a global scale, myocardial infarction (MI) remains one of the most important cardiological challenges of today due...
Oral L-Arginine (5 g/day) for 14 Days Improves Microcirculatory Function in Healthy Young Women and Healthy and Type 2 Diabetes Mellitus Elderly Women
J Vasc Res. 2021 Nov 16:1-10. doi: 10.1159/000519428. Online ahead of print. ABSTRACT OBJECTIVE: The aim of this study was to investigate the effect of...
Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
Exp Neurol. 2021 Nov 12;348:113923. doi: 10.1016/j.expneurol.2021.113923. Online ahead of print. ABSTRACT Arginase 1 (A1) is the enzyme that hydrolyzes the amino acid, L-arginine, to...
Roles of Endothelial Motilin Receptor and Its Signal Transduction Pathway in Motilin-Induced Left Gastric Artery Relaxation in Dogs
Front Physiol. 2021 Oct 28;12:770430. doi: 10.3389/fphys.2021.770430. eCollection 2021. ABSTRACT Background: Motilin increases left gastric artery (LGA) blood flow in dogs via the endothelial motilin...
Folic acid, either solely or combined with L-citrulline, improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs
Physiol Rep. 2021 Nov;9(21):e15096. doi: 10.14814/phy2.15096. ABSTRACT Concomitant with developing pulmonary hypertension (PH), newborn piglets exposed to chronic hypoxia develop pulmonary vascular NO signaling impairments....
Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats
Biol Pharm Bull. 2021;44(12):1860-1865. doi: 10.1248/bpb.b21-00547. ABSTRACT An electrical communication between the endothelial and smooth muscle cells via gap junctions, which provides the signaling pathway...
SNHG12 regulates biological behaviors of ox-LDL-induced HA-VSMCs through upregulation of SPRY2 and NUB1
Atherosclerosis. 2021 Nov 8;340:1-11. doi: 10.1016/j.atherosclerosis.2021.11.006. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Human vascular smooth muscle cells (HA-VSMCs) are an important cell type...
Cyanidin-3-O-glucoside supplementation ameliorates metabolic insulin resistance via restoration of nitric oxide-mediated endothelial insulin transport
Mol Nutr Food Res. 2021 Nov 28:e2100742. doi: 10.1002/mnfr.202100742. Online ahead of print. ABSTRACT SCOPE: Anthocyanin cyanidin-3-O-glucoside (Cy3G) has a great potential in prevention of...
Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Placenta
Int J Endocrinol. 2021 Nov 15;2021:5017362. doi: 10.1155/2021/5017362. eCollection 2021. ABSTRACT Preeclampsia (PE) is one of the commonest causes for maternal and fetal morbidity and...
Hypolipaemic nutraceutics: red yeast rice and Armolipid, berberine and bergamot
Ann Agric Environ Med. 2021 Mar 18;28(1):81-88. doi: 10.26444/aaem/130629. Epub 2020 Dec 2. ABSTRACT INTRODUCTION: Increased serum cholesterol levels constitute one of the main risk...
Doctor, Do You Know Red Yeast Rice?
Praxis (Bern 1994). 2021;110(4):207-220. doi: 10.1024/1661-8157/a003617. ABSTRACT Doctor, Do You Know Red Yeast Rice? Abstract. We present cases of patients with high total cholesterol who...