Bringing the Spotlight to tau and TDP-43 in Frontotemporal Dementia: A Review of Promising Chemical Compounds
Curr Med Chem. 2022 May 8. doi: 10.2174/0929867329666220508175340. Online ahead of print. ABSTRACT There is a wide variety of neurodegenerative diseases, among which frontotemporal dementia...
The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS)
Am J Clin Nutr. 2022 May 1;115(5):1270-1281. doi: 10.1093/ajcn/nqac001. ABSTRACT BACKGROUND: The effect of diet on age-related brain atrophy is largely unproven. OBJECTIVES: We aimed...
Protective Effect of L-Arginine in an Animal Model of Alzheimer’s Disease Induced by Intra-Hippocampal Injection of AlCl3
Neurol India. 2022 Mar-Apr;70(2):548-553. doi: 10.4103/0028-3886.344672. ABSTRACT BACKGROUND AND OBJECTIVE: Aluminum chloride (AlCl3) can impair spatial memory recovery. We investigated the protective effect of L-arginine,...
Research progress of Curcuma kwangsiensis root tubers and analysis of liver protection and anti-tumor mechanisms based on Q-markers
Zhongguo Zhong Yao Za Zhi. 2022 Apr;47(7):1739-1753. doi: 10.19540/j.cnki.cjcmm.20211220.203. ABSTRACT Curcuma kwangsiensis root tuber is a widely used genuine medicinal material in Guangxi, with the...
Micronized Curcumin Causes Hyperlocomotion in Zebrafish Larvae
Neurochem Res. 2022 May 10. doi: 10.1007/s11064-022-03618-9. Online ahead of print. ABSTRACT Zebrafish larvae have been widely used in neuroscience and drug research and development....
Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats
Chem Biodivers. 2022 May 10. doi: 10.1002/cbdv.202200029. Online ahead of print. ABSTRACT Increasing evidence suggested that inhibiting the apoptosis of Schwann cells (SCs) and promoting...
[Corrigendum] Quercetin protects rat cortical neurons against traumatic brain injury
Mol Med Rep. 2022 Jul;26(1):216. doi: 10.3892/mmr.2022.12732. Epub 2022 May 11. ABSTRACT Subsequently to the publication of the above paper, an interested reader drew to...
A review of biologically active flavonoids as inducers of autophagy and apoptosis in neoplastic cells and as cytoprotective agents in non-neoplastic cells
Cell Biol Int. 2022 May 11. doi: 10.1002/cbin.11813. Online ahead of print. ABSTRACT Phytochemicals are a diverse group of compounds found in various fruits, vegetables,...
The Effects of Blackcurrant and Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R2805. ABSTRACT BACKGROUND: Cardiovascular disease (CVD) is the number one cause of morbidity and mortality for both men...
Screening of Non-Purine Ligands Binding to Adenosine Receptors A1 , A2A , A2B , and A3
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4816. ABSTRACT Adenosine receptors (ARs) are G-protein coupled receptors (GPCRs) which have been shown to have therapeutic potential....
The Effect of Curcumin on Idiopathic Parkinson Disease: A Clinical and Skin Biopsy Study
J Neuropathol Exp Neurol. 2022 May 13:nlac034. doi: 10.1093/jnen/nlac034. Online ahead of print. ABSTRACT There are currently no standardized therapies for Parkinson disease (PD). Curcumin...
Potential Drug Therapy For Fragile X Tremor/Ataxia Syndrome
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R6346. ABSTRACT Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurological disorder that affects carriers of the alleles...
The Effects of Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells: A Potential Cardioprotective and Neuroprotective Mechanism
Molecules. 2022 Apr 27;27(9):2789. doi: 10.3390/molecules27092789. ABSTRACT Oxidative stress is a key underlying factor in cognitive decline and atherosclerosis. Oxidative stress occurs at the cellular...
In-Vitro Antioxidant Assays and Computational Investigation of Phytoconstituents from Theobroma cacao Beans as Inhibitors of Neuro-Modulatory Enzymes
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7613. ABSTRACT Neurodegenerative disease (ND) is a heterogeneous group of disorders characterized by progressive deterioration of neuronal cells...
Biodegradable Nanoparticles Loaded with Levodopa and Curcumin for Treatment of Parkinson’s Disease
Molecules. 2022 Apr 28;27(9):2811. doi: 10.3390/molecules27092811. ABSTRACT Background: Parkinson’s disease (PD) is the second most common age-related neurodegenerative disorder. Levodopa (L-DOPA) remains the gold-standard drug...