Cannabis use is associated with reduced access to kidney transplantation and an increased risk of acute rejection post-transplant
Clin Transplant. 2024 Feb;38(2):e15264. doi: 10.1111/ctr.15264. ABSTRACT BACKGROUND: The association between cannabis use and access to waitlisting, transplantation, and post-transplant outcomes remains uncertain. METHODS: Patients...
Effect of cannabis use on blood levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF): A systematic review and meta-analysis
Brain Behav. 2024 Jan;14(1):e3340. doi: 10.1002/brb3.3340. ABSTRACT BACKGROUND: The impact of cannabis uses on blood levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor...
Is dependent cannabis use in adult hospitalizations with inflammatory bowel disease associated with major adverse cardiovascular and cerebrovascular events? Insights from National Inpatient Sample Analysis
Curr Med Res Opin. 2024 Feb 20:1-13. doi: 10.1080/03007995.2024.2321328. Online ahead of print. ABSTRACT BACKGROUND: Inflammatory bowel disease (IBD) and dependent cannabis use or cannabis...
Comparing dietary strategies to manage cardiovascular risk in primary care: a narrative review of systematic reviews
Br J Gen Pract. 2024 Feb 19:BJGP.2022.0564. doi: 10.3399/BJGP.2022.0564. Online ahead of print. ABSTRACT BACKGROUND: Nutrition care in general practice is crucial for cardiovascular disease...
Gut-brain communication mediates the impact of dietary lipids on cognitive capacity
Food Funct. 2024 Feb 19;15(4):1803-1824. doi: 10.1039/d3fo05288e. ABSTRACT Cognitive impairment, as a prevalent symptom of nervous system disorders, poses one of the most challenging aspects...
Effects of the ApoE genotype on cognitive function in aging mice fed with a high-fat diet and the protective potential of n-3 polyunsaturated fatty acids
Food Funct. 2024 Feb 19;15(4):2249-2264. doi: 10.1039/d3fo03965j. ABSTRACT The ApoE4 allele is the strongest genetic determinant for Alzheimer’s disease (AD), while obesity is a strong...
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice
Transl Psychiatry. 2024 Feb 19;14(1):101. doi: 10.1038/s41398-024-02820-3. ABSTRACT G protein-coupled receptor 55 (GPR55) has been thought to be a putative cannabinoid receptor. However, little is...
Cutaneous targets for topical pain medications in patients with neuropathic pain: individual differential expression of biomarkers supports the need for personalized medicine
Pain Rep. 2024 Feb 16;9(2):e1119. doi: 10.1097/PR9.0000000000001121. eCollection 2024 Apr. ABSTRACT INTRODUCTION: Numerous potential cutaneous targets exist for treating chronic pain with topically applied active...
Under explored roles of microbial ligninolytic enzymes in aerobic polychlorinated biphenyl transformation
Environ Sci Pollut Res Int. 2024 Feb 19. doi: 10.1007/s11356-024-32291-4. Online ahead of print. ABSTRACT Polychlorinated biphenyls (PCBs) are persistent organic pollutants in the environment...
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo
ACS Chem Neurosci. 2024 Feb 19. doi: 10.1021/acschemneuro.3c00656. Online ahead of print. ABSTRACT Alzheimer’s disease (AD) is a neurodegenerative form of dementia characterized by the...
Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB2 Receptor
Chembiochem. 2024 Feb 19:e202300785. doi: 10.1002/cbic.202300785. Online ahead of print. ABSTRACT The cannabinoid receptor type 2 (CB2R) is a G protein-coupled receptor with therapeutic potential...
Stability, biofunctional, and antimicrobial characteristics of cannabidiol isolate for the design of topical formulations
Soft Matter. 2024 Feb 19. doi: 10.1039/d3sm01466e. Online ahead of print. ABSTRACT Cannabidiol (CBD) is a high-value natural compound of Cannabis Sativa plant. It is...
Dietary docosahexaenoic acid supplementation inhibits acute pulmonary transcriptional and autoantibody responses to a single crystalline silica exposure in lupus-prone mice
Front Immunol. 2024 Feb 1;15:1275265. doi: 10.3389/fimmu.2024.1275265. eCollection 2024. ABSTRACT INTRODUCTION: Workplace exposure to respirable crystalline silica (cSiO2) has been epidemiologically linked to lupus. Consistent...
Dietary docosahexaenoic acid supplementation inhibits acute pulmonary transcriptional and autoantibody responses to a single crystalline silica exposure in lupus-prone mice
Front Immunol. 2024 Feb 1;15:1275265. doi: 10.3389/fimmu.2024.1275265. eCollection 2024. ABSTRACT INTRODUCTION: Workplace exposure to respirable crystalline silica (cSiO2) has been epidemiologically linked to lupus. Consistent...
Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis
Microbiome. 2024 Feb 17;12(1):28. doi: 10.1186/s40168-024-01749-5. ABSTRACT BACKGROUND: Bisphenol A (BPA) is an environmental contaminant with endocrine-disrupting properties that induce fetal growth restriction (FGR). Previous...