MAGL protects against renal fibrosis through inhibiting tubular cell lipotoxicity
Theranostics. 2024 Feb 4;14(4):1583-1601. doi: 10.7150/thno.92848. eCollection 2024. ABSTRACT Rationale: Renal fibrosis, with no therapeutic approaches, is a common pathological feature in various chronic kidney...
Craving dynamics and related cerebral substrates predict timing of use in alcohol, tobacco, and cannabis use disorders
Addict Neurosci. 2023 Dec 15;9:100138. doi: 10.1016/j.addicn.2023.100138. Epub 2023 Nov 17. ABSTRACT BACKGROUND: Patients treated for Substance Use Disorders exhibit highly fluctuating patterns of craving...
The interaction of Suk-Saiyasna remedy with GABAA and CB1 receptor-targeting drugs: Enhancing hypnotic and sedative effects in in vivo models
J Adv Pharm Technol Res. 2024 Jan-Mar;15(1):13-18. doi: 10.4103/JAPTR.JAPTR_355_23. Epub 2024 Jan 15. ABSTRACT The Suk-Saiyasna remedy, an herbal treatment, was historically used but ceased...
CB1 Cannabinoid Receptor is a Target for Neuroprotection in Light Induced Retinal Degeneration
Adv Drug Alcohol Res. 2022 Sep 13;2:10734. doi: 10.3389/adar.2022.10734. eCollection 2022. ABSTRACT In the last few years, an increasing interest in the neuroprotective effect of...
Therapeutic-like activity of cannabidiolic acid methyl ester in the MK-801 mouse model of schizophrenia: Role for cannabinoid CB1 and serotonin-1A receptors
Eur J Neurosci. 2024 Feb 22. doi: 10.1111/ejn.16278. Online ahead of print. ABSTRACT Schizophrenia is a psychotic disorder with an increasing prevalence and incidence over...
Recent Advances in Management of Neuropathic, Nociceptive, and Chronic Pain: A Narrative Review with Focus on Nanomedicine, Gene Therapy, Stem Cell Therapy, and Newer Therapeutic Options
Curr Pain Headache Rep. 2024 Feb 22. doi: 10.1007/s11916-024-01227-5. Online ahead of print. ABSTRACT PURPOSE OF REVIEW: This manuscript summarizes novel clinical and interventional approaches...
Stress-induced stenotic vascular remodeling via reduction of plasma omega-3 fatty acid metabolite 4-oxoDHA by noradrenaline
Sci Rep. 2024 Feb 20;14(1):4178. doi: 10.1038/s41598-024-54867-3. ABSTRACT Stress has garnered significant attention as a prominent risk factor for inflammation-related diseases, particularly cardiovascular diseases (CVDs)....
The Biosynthesis of Astaxanthin Esters in Schizochytrium sp. is Mediated by a Bifunctional Diacylglycerol Acyltransferase
J Agric Food Chem. 2024 Feb 21;72(7):3584-3595. doi: 10.1021/acs.jafc.3c09086. Epub 2024 Feb 12. ABSTRACT Astaxanthin esters are a major form of astaxanthin found in nature....
Mucociliary transport in cystic fibrosis
Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2400674121. doi: 10.1073/pnas.2400674121. Epub 2024 Feb 20. NO ABSTRACT PMID:38377219 | DOI:10.1073/pnas.2400674121...
Stress-induced stenotic vascular remodeling via reduction of plasma omega-3 fatty acid metabolite 4-oxoDHA by noradrenaline
Sci Rep. 2024 Feb 20;14(1):4178. doi: 10.1038/s41598-024-54867-3. ABSTRACT Stress has garnered significant attention as a prominent risk factor for inflammation-related diseases, particularly cardiovascular diseases (CVDs)....
A novel polysaccharide isolated from Coriolus versicolor polarizes M2 macrophages into an M1 phenotype and reversesits immunosuppressive effect on tumor microenvironment
Int J Biol Macromol. 2024 Feb;259(Pt 2):129352. doi: 10.1016/j.ijbiomac.2024.129352. Epub 2024 Jan 11. ABSTRACT Converting M2 macrophages into an M1 phenotype in the tumor microenvironment,...
Synergistic antidepressant-like effect of citicoline and CB 1 agonist in male mice
Psychopharmacology (Berl). 2024 Feb 21. doi: 10.1007/s00213-023-06507-3. Online ahead of print. ABSTRACT BACKGROUND: The endocannabinoid system plays a key role in the control of many...
Association effect of the phytocannabinoid beta-caryophyllene and indomethacin carried in topical nanoemulgels: an evaluation by in vivo anti-inflammatory model
Nat Prod Res. 2024 Feb 21:1-7. doi: 10.1080/14786419.2024.2317887. Online ahead of print. ABSTRACT The sesquiterpene β-caryophyllene, classified as a phytocannabinoid compound, has been widely studied...
Associations between cannabis policies and state-level specialty cannabis use disorder treatment in the United States, 2004-2019
Drug Alcohol Depend. 2024 Feb 2;257:111113. doi: 10.1016/j.drugalcdep.2024.111113. Online ahead of print. ABSTRACT BACKGROUND: Cannabis use disorder (CUD) treatment prevalence decreased in the US between...
Reduced Diffusivity Along Perivascular Spaces on Magnetic Resonance Imaging Associated with Younger Age of First Use and Cognitive Impairment in Recreational Marijuana Users
AJNR Am J Neuroradiol. 2024 Feb 21:ajnr.A8215. doi: 10.3174/ajnr.A8215. Online ahead of print. ABSTRACT BACKGROUND AND PURPOSE: The impairment of the glymphatic system, a perivascular...