Essential role of protein kinase C betaI in icariin-mediated protection against atherosclerosis
J Pharm Pharmacol. 2021 Aug 12;73(9):1169-1179. doi: 10.1093/jpp/rgab040. ABSTRACT OBJECTIVES: This study aimed to clarify the superior beneficial effects of icariin on atherosclerosis, as well...
Inhibitory mechanism of icariin against oxidative stress-induced calcification in aortic vascular smooth muscle cells
Zhongguo Zhong Yao Za Zhi. 2021 Sep;46(17):4497-4503. doi: 10.19540/j.cnki.cjcmm.20210603.406. ABSTRACT This study aimed to observe the inhibitory effect of icariin against oxidative stress-induced calcification in...
Icariin activates autophagy to trigger TGFbeta1 upregulation and promote angiogenesis in EA.hy926 human vascular endothelial cells
Bioengineered. 2021 Nov 30. doi: 10.1080/21655979.2021.2011637. Online ahead of print. ABSTRACT Angiogenesis plays an important role in tissue development and repair, and how to regulate...
Phytochemical and biological assessments on Lipidium meyenii (maca) and Epimidium sagittatum (horny goat weed)
Pak J Pharm Sci. 2017 Jan;30(1):29-36. ABSTRACT The effects of Lipidium meyenii (maca, LM) and Epimidium sagittatum (horny goat weed, ES) have been investigated due...
Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed
Front Pharmacol. 2017 Oct 12;8:734. doi: 10.3389/fphar.2017.00734. eCollection 2017. ABSTRACT Icariin is a major bioactive pharmaceutical constituent isolated from Chinese medicine Horny Goat Weed (Ying...
The antiosteoporosis effect of icariin in ovariectomized rats: a systematic review and meta-analysis
Cell Mol Biol (Noisy-le-grand). 2017 Nov 30;63(11):124-131. doi: 10.14715/cmb/2017.63.11.22. ABSTRACT Herba Epimedii (Yinyanghuo or Horny Goat Weed) is a traditional Chinese medicine widely used in...
Mania Associated With Herbal Medicines, Other Than Cannabis: A Systematic Review and Quality Assessment of Case Reports
Front Psychiatry. 2018 Jul 6;9:280. doi: 10.3389/fpsyt.2018.00280. eCollection 2018. ABSTRACT Background: DSM-5 introduced the diagnostic category of substance/medication-induced bipolar and related disorder. This systematic review...
Icariin alleviates murine lupus nephritis via inhibiting NF-κB activation pathway and NLRP3 inflammasome
Life Sci. 2018 Sep 1;208:26-32. doi: 10.1016/j.lfs.2018.07.009. Epub 2018 Jul 6. ABSTRACT AIMS: Lupus nephritis (LN) is a kidney inflammatory disease caused by systemic lupus...
An outline for the pharmacological effect of icariin in the nervous system
Eur J Pharmacol. 2019 Jan 5;842:20-32. doi: 10.1016/j.ejphar.2018.10.006. Epub 2018 Oct 19. ABSTRACT Icariin is a major active component of the traditional herb Epimedium, also...
An Analysis of Popular Online Erectile Dysfunction Supplements
J Sex Med. 2019 Jun;16(6):843-852. doi: 10.1016/j.jsxm.2019.03.269. Epub 2019 Apr 26. ABSTRACT INTRODUCTION: Erectile dysfunction supplements (ED-Ss) are featured on online marketplaces like Amazon.com, with...
Angiogenic and MMPs modulatory effects of icariin improved cutaneous wound healing in rats
Eur J Pharmacol. 2019 Sep 5;858:172466. doi: 10.1016/j.ejphar.2019.172466. Epub 2019 Jun 17. ABSTRACT Icariin is a flavonoid from plant belonging to the genus Epimedium, commonly...
A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements
Int J Impot Res. 2021 Apr;33(3):311-317. doi: 10.1038/s41443-020-0285-x. Epub 2020 May 1. ABSTRACT The objective was to study available evidence for ingredients of popular over-the-counter...
Analysis of pharmacological mechanisms of Yinyanghuo as treatment of erectile dysfunction with network pharmacology-based strategy
Andrologia. 2021 Mar;53(2):e13943. doi: 10.1111/and.13943. Epub 2020 Dec 23. ABSTRACT Erectile dysfunction is considered an important health problem that impacts the quality of life of...
Case-control study on tibetan Baimai ointment (see symbol in text) for the treatment of wrist-dysfunction after distal radius fracture
Zhongguo Gu Shang. 2014 Nov;27(11):920-4. ABSTRACT OBJECTIVE: To evaluate efficacy and safety of Baimai ointment (see symbol in text) in the treatment of wrist-dysfunction after...
In vitro transdermal permeation of main compositions in Baimai Ointment
Zhongguo Zhong Yao Za Zhi. 2019 Jun;44(12):2486-2492. doi: 10.19540/j.cnki.cjcmm.20190221.008. ABSTRACT To establish a determination method for the contents of ammonium glycyrrhetate,nardosinone,and curcumin in transdermal receptor...