Eicosanoid lipidome activation in post-mortem brain tissues of individuals with APOE4 and Alzheimer’s dementia
Alzheimers Res Ther. 2022 Oct 11;14(1):152. doi: 10.1186/s13195-022-01084-7. ABSTRACT BACKGROUND: Chronic neuroinflammation is one of the hallmarks of late-onset Alzheimer’s disease (AD) dementia pathogenesis. Carrying...
Increases in plasma n-3 tetracosapentaenoic acid and tetracosahexaenoic acid following 12 weeks of EPA, but not DHA, supplementation in women and men
Prostaglandins Leukot Essent Fatty Acids. 2022 Oct;185:102494. doi: 10.1016/j.plefa.2022.102494. Epub 2022 Sep 15. ABSTRACT Dietary feeding and stable isotope studies in rodents support that the...
The Copenhagen Actinic Keratosis Study (COAKS). A decentralised clinical trial to evaluate tolerability, safety and efficacy of daily field-directed topical treatment with cytosolic phospholipase A2 inhibitor, AVX001, in participants with actinic keratosis: protocol for a randomised controlled phase I/IIa trial
BMJ Open. 2022 Oct 5;12(10):e061012. doi: 10.1136/bmjopen-2022-061012. ABSTRACT INTRODUCTION: Actinic keratosis (AK) is the most common precancerous skin condition caused by long-term UV exposure. Given...
A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes
PLoS One. 2022 Oct 6;17(10):e0273987. doi: 10.1371/journal.pone.0273987. eCollection 2022. ABSTRACT BACKGROUND: The diversity found in the chemical compounds of a single species in different regions...
Impact of dietary Chlorella vulgaris and feed enzymes on health status, immune response and liver metabolites in weaned piglets
Sci Rep. 2022 Oct 7;12(1):16816. doi: 10.1038/s41598-022-21238-9. ABSTRACT In this study, we analysed the impact of dietary inclusion of Chlorella vulgaris and carbohydrases on general...
Effects of white mustard (Sinapis alba) Oil on growth performance, immune response, blood parameters, digestive and antioxidant enzyme activities in rainbow trout (Oncorhynchusmykiss)
Fish Shellfish Immunol. 2022 Oct 6:S1050-4648(22)00649-0. doi: 10.1016/j.fsi.2022.10.006. Online ahead of print. ABSTRACT A study was conducted to evaluate the effects of dietary supplementation of...
Anti-inflammatory effect of fucoidan isolated from fermented Sargassum fusiforme in in vitro and in vivo models
Int J Biol Macromol. 2022 Oct 5:S0141-8130(22)02234-6. doi: 10.1016/j.ijbiomac.2022.10.005. Online ahead of print. ABSTRACT Fucoidans possess potent anti-inflammatory effects. In the present study, the anti-inflammatory...
The protective effect of Moringa oleifera plant extract against glutamate-induced DNA damage and reduced cell viability in a primary retinal ganglion cell line
PeerJ. 2021 Jun 22;9:e11569. doi: 10.7717/peerj.11569. eCollection 2021. ABSTRACT BACKGROUND: Glutamate excitotoxicity can cause DNA damage and is linked to many retinal and neurological disorders....
The ameliorative effect of Moringa oleifera oil on tributyltin-induced brain toxicity in albino rats
Environ Toxicol. 2021 Oct;36(10):2025-2039. doi: 10.1002/tox.23320. Epub 2021 Jul 6. ABSTRACT Tributyltin (TBT) is an organotin compound widely used as a biocide in antifouling paints....
Long-term consumption of Moringa oleifera-supplemented diet enhanced neurocognition, suppressed oxidative stress, acetylcholinesterase activity and neuronal degeneration in rat’s hippocampus
Drug Metab Pers Ther. 2021 Mar 26;36(3):223-231. doi: 10.1515/dmpt-2020-0189. ABSTRACT OBJECTIVES: This study investigates protection against oxidative stress and memory enhancing potential of long-term consumption...
Moringa oleifera-supplemented diet protect against cortico-hippocampal neuronal degeneration in scopolamine-induced spatial memory deficit in mice: role of oxido-inflammatory and cholinergic neurotransmission pathway
Metab Brain Dis. 2021 Dec;36(8):2445-2460. doi: 10.1007/s11011-021-00855-9. Epub 2021 Oct 20. ABSTRACT The therapeutic and pharmacological management of Alzheimer’s disease (AD) is generally considered a...
Effects of spicy leaves on cognitive function and apoptosis of hippocampal neurons in diabetic rats
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2021 Nov;37(6):638-643. doi: 10.12047/j.cjap.6123.2021.070. ABSTRACT Objective: To investigate the effects of Moringa leaves on the cognitive dysfunction...
Influence of Moringa (Moringa oleifera) enriched ice creams on rats’ brain: Exploring the redox and cholinergic systems
Curr Res Food Sci. 2022 Feb 3;5:366-373. doi: 10.1016/j.crfs.2022.01.021. eCollection 2022. ABSTRACT The broad application of Moringa oleifera leaves in the treatment of numerous diseases...
Effects of Moringa oleifera in Two Independents Formulation and as Neuroprotective Agent Against Scopolamine-Induced Memory Impairment in Mice
Front Nutr. 2022 Mar 1;9:799127. doi: 10.3389/fnut.2022.799127. eCollection 2022. ABSTRACT BACKGROUND: The cognitive deficit has frequently been found in the elderly population. Several studies have...
Computational screening of phytochemicals from three medicinal plants as inhibitors of transmembrane protease serine 2 implicated in SARS-CoV-2 infection
Phytomed Plus. 2021 Nov;1(4):100135. doi: 10.1016/j.phyplu.2021.100135. Epub 2021 Sep 29. ABSTRACT BACKGROUND: SARS-CoV-2 infection or COVID-19 is a major global public health issue that requires...