Medical cannabinoids for painful symptoms in patients with severe dementia: a randomized, double-blind cross-over placebo-controlled trial protocol
Front Pain Res (Lausanne). 2023 May 24;4:1108832. doi: 10.3389/fpain.2023.1108832. eCollection 2023. ABSTRACT BACKGROUND: In an observational study in Geneva (Switzerland), we found that administering a...
The impact of early factors on persistent negative symptoms in youth at clinical high risk for psychosis
Front Psychiatry. 2023 May 24;14:1125168. doi: 10.3389/fpsyt.2023.1125168. eCollection 2023. ABSTRACT INTRODUCTION: Persistent negative symptoms (PNS) are described as continuing moderate negative symptoms. More severe negative...
Medical cannabinoids for painful symptoms in patients with severe dementia: a randomized, double-blind cross-over placebo-controlled trial protocol
Front Pain Res (Lausanne). 2023 May 24;4:1108832. doi: 10.3389/fpain.2023.1108832. eCollection 2023. ABSTRACT BACKGROUND: In an observational study in Geneva (Switzerland), we found that administering a...
Cannabis regulatory system in European Union countries, forensic concept of “doping dose” and medico-legal implications
Med Leg J. 2023 Jun 9:258172231166272. doi: 10.1177/00258172231166272. Online ahead of print. ABSTRACT Cannabis is the most widely used illicit psychoactive substance in the world....
Social media use and cannabis vaping initiation among US youth
Drug Alcohol Depend. 2023 Jun 1;249:109949. doi: 10.1016/j.drugalcdep.2023.109949. Online ahead of print. ABSTRACT BACKGROUND: Youth cannabis vaping has increased in recent years, and there is...
Anandamide improves food intake and orexinergic neuronal activity in the chronic sleep deprivation induction model in rats by modulating the expression of the CB1 receptor in the lateral hypothalamus
Neuropeptides. 2023 Apr 20;101:102336. doi: 10.1016/j.npep.2023.102336. Online ahead of print. ABSTRACT Sleep deprivation alters orexinergic neuronal activity in the lateral hypothalamus (LH), which is the...
Potential neonatal toxicity of new psychoactive substances
Pharmacol Ther. 2023 Jun 6:108468. doi: 10.1016/j.pharmthera.2023.108468. Online ahead of print. ABSTRACT Cannabis, cocaine, 3,4-methylenedioxymethamphetamine, and lysergic acid diethylamide are psychoactive substances with a significant...
The current role of cannabis and cannabinoids in health: A comprehensive review of their therapeutic potential
Life Sci. 2023 Jun 6:121838. doi: 10.1016/j.lfs.2023.121838. Online ahead of print. ABSTRACT There has been an increased interest of the scientific community in cannabis and...
Integrating a Systematic, Comprehensive E-Cigarette and Vaping Assessment Tool into the Electronic Health Record
J Am Board Fam Med. 2023 May 8;36(3):405-413. doi: 10.3122/jabfm.2022.220410R1. ABSTRACT BACKGROUND: Recently, the use of electronic cigarettes increased sharply, leading to increased e-cigarette, or...
Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials
Nat Med. 2023 Jun 8. doi: 10.1038/s41591-023-02381-w. Online ahead of print. ABSTRACT Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate...
Compound from Magnolia officinalis Ameliorates White Matter Injury by Promoting Oligodendrocyte Maturation in Chronic Cerebral Ischemia Models
Neurosci Bull. 2023 Jun 9. doi: 10.1007/s12264-023-01068-z. Online ahead of print. ABSTRACT Chronic cerebral hypoperfusion leads to white matter injury (WMI), which subsequently causes neurodegeneration...
Reasonable access: important characteristics and perceived quality of legal and illegal sources of cannabis for medical purposes in Canada
J Cannabis Res. 2023 Jun 9;5(1):18. doi: 10.1186/s42238-023-00185-w. ABSTRACT BACKGROUND: Throughout the past two decades of legal medical cannabis in Canada, individuals have experienced challenges...
The Cannabis Effects Expectancy Questionnaire-Medical (CEEQ-M): Preliminary psychometric properties and longitudinal validation within a clinical trial
Psychol Assess. 2023 Jun 8. doi: 10.1037/pas0001244. Online ahead of print. ABSTRACT The use of cannabis for medical symptoms is increasing despite limited evidence for...
Effects of hypnosis, mindfulness meditation, and education for chronic pain on substance use in veterans: A supplementary analysis of a randomized clinical trial
Rehabil Psychol. 2023 Jun 8. doi: 10.1037/rep0000507. Online ahead of print. ABSTRACT PURPOSE/OBJECTIVE: To examine the impact of three behavioral interventions for chronic pain on...
Docosahexaenoic Acid Alters Lipid Metabolism Processes via H3K9ac Epigenetic Modification in Dairy Goat
J Agric Food Chem. 2023 Jun 7;71(22):8527-8539. doi: 10.1021/acs.jafc.3c01606. Epub 2023 May 24. ABSTRACT Goat milk is increasingly recognized by consumers due to its high...