Icosapent ethyl therapy for very high triglyceride levels: a 12-week, multi-center, placebo-controlled, randomized, double-blinded, phase III clinical trial in China
Lipids Health Dis. 2023 Jun 10;22(1):71. doi: 10.1186/s12944-023-01838-8. ABSTRACT OBJECTIVES: Eicosapentaenoic acid in its ethyl ester form is the single active component of icosapent ethyl...
Transcriptom and miRNA data of PUFA-enriched stimulated murine macrophage and human endothelial cell lines
Sci Data. 2023 Jun 10;10(1):375. doi: 10.1038/s41597-023-02288-8. ABSTRACT Inflammation is associated with the adaptation of macrophages and endothelial cells, and the dysregulation of these differentiation...
Unsaturated fatty acids uniquely alter aggregation rate of α-synuclein and insulin and change the secondary structure and toxicity of amyloid aggregates formed in their presence
FASEB J. 2023 Jul;37(7):e22972. doi: 10.1096/fj.202300003R. ABSTRACT Docosahexaenoic (DHA) and arachidonic acids (ARA) are omega-3 and omega-6 long-chain polyunsaturated fatty acids (LCPUFAs). These molecules constitute...
Antidepressant effects of p-coumaric acid isolated from Vaccinium bracteatum leaves extract on chronic restraint stress mouse model and antagonism of serotonin 6 receptor in vitro
Phytomedicine. 2023 Jul 25;116:154871. doi: 10.1016/j.phymed.2023.154871. Epub 2023 May 10. ABSTRACT BACKGROUND: Vaccinium bracteatum Thunb. leaves (VBL) are used in traditional herbal medicines to treat...
Evaluation of the Analgesic Effect of High-Cannabidiol-Content Cannabis Extracts in Different Pain Models by Using Polymeric Micelles as Vehicles
Molecules. 2023 May 24;28(11):4299. doi: 10.3390/molecules28114299. ABSTRACT Currently, cannabis is considered an attractive option for the treatment of various diseases, including pain management. Thus, developing...
A systematic review of in utero cannabis exposure and risk for structural birth defects
Front Pediatr. 2023 May 25;11:1149401. doi: 10.3389/fped.2023.1149401. eCollection 2023. ABSTRACT INTRODUCTION: Cannabis use among pregnant women has increased over time. Therefore, there is a great...
Mental health adverse events with cannabis use diagnosed in the Emergency Department: what are we finding now and are our findings accurate?
Front Psychiatry. 2023 May 25;14:1093081. doi: 10.3389/fpsyt.2023.1093081. eCollection 2023. ABSTRACT We have previously reviewed the types and numbers of cannabis-associated adverse events that have mental...
THC exposure during adolescence increases impulsivity-like behavior in adulthood in a WIN 55,212-2 self-administration mouse model
Front Psychiatry. 2023 May 25;14:1148993. doi: 10.3389/fpsyt.2023.1148993. eCollection 2023. ABSTRACT BACKGROUND: Cannabis addiction is a chronically relapsing disorder lacking effective treatment. Regular cannabis consumption typically...
Hair Regrowth with Novel Hemp Extract: A Case Series
Int J Trichology. 2023 Jan-Feb;15(1):18-24. doi: 10.4103/ijt.ijt_34_22. Epub 2023 Apr 19. ABSTRACT INTRODUCTION: The endocannabinoid system (ECS), discovered in the 1990s, is a system involved...
Endocannabinoid system components as potential neuroimmune therapeutic targets in tinnitus
Front Neurol. 2023 May 25;14:1148327. doi: 10.3389/fneur.2023.1148327. eCollection 2023. ABSTRACT Research interest in understanding tinnitus has increased severalfold in the last decade to find a...
Evaluating preferences for online psychological interventions to decrease cannabis use in young adults with psychosis: An observational study
Psychiatry Res. 2023 May 30;326:115276. doi: 10.1016/j.psychres.2023.115276. Online ahead of print. ABSTRACT Innovative technology-based solutions have the potential to improve access to clinically proven interventions...
A tale of two cities: Racialized arrests following decriminalization and recreational legalization of cannabis
Drug Alcohol Depend. 2023 May 6;249:109911. doi: 10.1016/j.drugalcdep.2023.109911. Online ahead of print. ABSTRACT BACKGROUND: In the U.S., “War on Drugs” policies have led to large...
What’s your cup of tea? The role of herbal compounds in the management of multiple sclerosis
Mult Scler Relat Disord. 2023 Jun 7;76:104799. doi: 10.1016/j.msard.2023.104799. Online ahead of print. ABSTRACT Multiple Sclerosis (MS) is a chronic, inflammatory, neurodegenerative disease that is...
Tenebrio molitor (Linnaeus, 1758): Microbiological Screening of Feed for a Safe Food Choice
Foods. 2023 May 25;12(11):2139. doi: 10.3390/foods12112139. ABSTRACT As a result of the increasing focus on alternative protein sources which are ideally still sustainable, the yellow...
Endogenous n-Alkanes in Vegetable Oils: Validation of a Rapid Offline SPE-GC-FID Method, Comparison with Online LC-GC-FID and Potential for Olive Oil Quality Control
Molecules. 2023 May 28;28(11):4393. doi: 10.3390/molecules28114393. ABSTRACT The potential of endogenous n-alkane profiling for the assessment of extra virgin olive oils (EVOO) adulteration (blends with...