Macrofungal Extracts as a Source of Bioactive Compounds for Cosmetical Anti-Aging Therapy: A Comprehensive Review
Nutrients. 2024 Aug 22;16(16):2810. doi: 10.3390/nu16162810. ABSTRACT For centuries, mushrooms have been used as a component of skincare formulations. Environmental stresses and a modern lifestyle...
Fungal Coculture of Herpotrichia sp. and Trametes versicolor Induces Production of Diverse Metabolites with Anti-Parkinson’s Neuroprotective Activity
J Nat Prod. 2024 Aug 30. doi: 10.1021/acs.jnatprod.4c00421. Online ahead of print. ABSTRACT Co-cultivation of isopod-associated fungi Herpotrichia sp. SF09 and Trametes versicolor SF09A led...
Development of an accelerated ageing protocol for the study of phytocannabinoid stability in Cannabis sativa L
J Pharm Biomed Anal. 2024 Aug 14;251:116422. doi: 10.1016/j.jpba.2024.116422. Online ahead of print. ABSTRACT Cannabis sativa L. is a plant belonging to the Cannabaceae family...
Delta-9-Tetrahydrocannabinol Blocks Bone Marrow-Derived Macrophage Differentiation through Elimination of Reactive Oxygen Species
Antioxidants (Basel). 2024 Jul 23;13(8):887. doi: 10.3390/antiox13080887. ABSTRACT Macrophages are vital components of the immune system and serve as the first line of defense against...
A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Effectiveness and Safety of Melatonin and Three Formulations of Floraworks Proprietary TruCBN™ for Improving Sleep
Pharmaceuticals (Basel). 2024 Jul 24;17(8):977. doi: 10.3390/ph17080977. ABSTRACT The phytocannabinoid cannabinol (CBN) has a potential mechanism of action as an alternative sleep aid but there...
Anti-inflammatory effects of phytocannabinoids and terpenes on inflamed Tregs and Th17 cells in vitro
Exp Mol Pathol. 2024 Aug 28;139:104924. doi: 10.1016/j.yexmp.2024.104924. Online ahead of print. ABSTRACT AIMS: Phytocannabinoids and terpenes from Cannabis sativa have demonstrated limited anti-inflammatory and...
Determination of Cannabinoids in Meat Products and Animal Feeds in Singapore Using Liquid Chromatography-Tandem Mass Spectrometry
Foods. 2024 Aug 18;13(16):2581. doi: 10.3390/foods13162581. ABSTRACT There has been a growing interest in the use of hemp as an animal feed ingredient considering its...
Rapid In Situ Near-Infrared Assessment of Tetrahydrocannabinolic Acid in Cannabis Inflorescences before Harvest Using Machine Learning
Sensors (Basel). 2024 Aug 6;24(16):5081. doi: 10.3390/s24165081. ABSTRACT Cannabis is cultivated for therapeutic and recreational purposes where delta-9 tetrahydrocannabinol (THC) is a main target for...
Total Synthesis of the Dimeric Phytocannabinoid Cannabitwinol (CBD Dimer) and Its Analogues
J Nat Prod. 2024 Aug 26. doi: 10.1021/acs.jnatprod.4c00674. Online ahead of print. ABSTRACT A new synthetic route to access the natural product phytocannabinoid cannabitwinol (1)...
Use of phytocanabinoids in animal models of parkinson’s disease: systematic review
Neurotoxicology. 2024 Aug 23:S0161-813X(24)00098-6. doi: 10.1016/j.neuro.2024.08.002. Online ahead of print. ABSTRACT This systematic review was carried out with the aim of evaluating the use of...
Dose-dependent effects of oral cannabidiol and delta-9-tetrahydrocannabinol on serum anandamide and related N-acylethanolamines in healthy volunteers
BMJ Ment Health. 2024 Aug 25;27(1):e301027. doi: 10.1136/bmjment-2024-301027. ABSTRACT BACKGROUND: The mental health benefits of cannabidiol (CBD) are promising but can be inconsistent, in part...
Same, Yet Different: Towards Understanding Nutrient Use In Hemp- And Drug-Type Cannabis
J Exp Bot. 2024 Aug 24:erae362. doi: 10.1093/jxb/erae362. Online ahead of print. ABSTRACT Cannabis sativa L., one of humanity’s oldest cultivated crops, has a complex...
Endocannabinoid system and phytocannabinoids in the main species of veterinary interest: a comparative review
Vet Res Commun. 2024 Aug 20. doi: 10.1007/s11259-024-10509-7. Online ahead of print. ABSTRACT Since the discovery of the endocannabinoid system and due to the empirical...
Metabolic characterization and transcriptional profiling of polyphenols in Cannabis sativa L. inflorescences with different chemical phenotypes
Planta. 2024 Aug 20;260(4):76. doi: 10.1007/s00425-024-04505-z. ABSTRACT After the most comprehensive analysis of the phenolic composition in Cannabis reported to date, a total of 211...
Cannabidiol enhances socially transmitted food preference: a role of acetylcholine in the mouse basal forebrain
Psychopharmacology (Berl). 2024 Aug 19. doi: 10.1007/s00213-024-06670-1. Online ahead of print. ABSTRACT RATIONALE AND OBJECTIVE: Rodents acquire food information from their conspecifics and display a...