Cancer-Cachexia-Induced Human Skeletal Muscle Myotube Degeneration Is Prevented via Cannabinoid Receptor 2 Agonism In Vitro
Pharmaceuticals (Basel). 2023 Nov 8;16(11):1580. doi: 10.3390/ph16111580. ABSTRACT Cachexia syndrome, leading to reduced skeletal muscle and fat mass, is highly prevalent in cancer patients, resulting...
An Emerging Strategy for Neuroinflammation Treatment: Combined Cannabidiol and Angiotensin Receptor Blockers Treatments Effectively Inhibit Glial Nitric Oxide Release
Int J Mol Sci. 2023 Nov 13;24(22):16254. doi: 10.3390/ijms242216254. ABSTRACT Cannabidiol (CBD), the major non-psychoactive phytocannabinoid found in cannabis, has anti-neuroinflammatory properties. Despite the increasing...
The neutral CB1 antagonist AM6527 reduces ethanol seeking, binge-like consumption, reinforcing, and withdrawal effects in male and female mice
Psychopharmacology (Berl). 2023 Nov 25. doi: 10.1007/s00213-023-06500-w. Online ahead of print. ABSTRACT RATIONALE: Alcohol use disorder (AUD) is a debilitating physiological and psychiatric disorder which...
Cardiovascular Diseases and Marine Oils: A Focus on Omega-3 Polyunsaturated Fatty Acids and Polar Lipids
Mar Drugs. 2023 Oct 24;21(11):549. doi: 10.3390/md21110549. ABSTRACT Cardiovascular diseases (CVD) remain the leading cause of death across the globe, hence, establishing strategies to counteract...
Pre-Post Cannabis Legalization for Adult Use: A Trend Study of Two Cohorts of Young Adult Cannabis Users in Los Angeles
J Psychoactive Drugs. 2023 Nov 24:1-11. doi: 10.1080/02791072.2023.2282515. Online ahead of print. ABSTRACT Cannabis was legalized for adult use in California in 2016 for individuals...
Elucidation of GPR55-Associated Signaling behind THC and LPI Reducing Effects on Ki67-Immunoreactive Nuclei in Patient-Derived Glioblastoma Cells
Cells. 2023 Nov 17;12(22):2646. doi: 10.3390/cells12222646. ABSTRACT GPR55 is involved in many physiological and pathological processes. In cancer, GPR55 has been described to show accelerating...
The putative cannabinoid-secreting trichome of Trema micrantha (L.) Blume (Cannabaceae)
Protoplasma. 2023 Nov 24. doi: 10.1007/s00709-023-01907-w. Online ahead of print. ABSTRACT Trema, a genus of the popularly known Cannabaceae, has recently been the subject of...
EXPRESS: Cannabinoid Hyperemesis Syndrome: Prevalence and Management in an Era of Cannabis Legalization
J Investig Med. 2023 Nov 23:10815589231217495. doi: 10.1177/10815589231217495. Online ahead of print. ABSTRACT As more states legalize cannabinoid products for recreational use and medicinal purposes...
A Descriptive Analysis of Adverse Event Reports from the Quebec Cannabis Registry
Drug Saf. 2023 Nov 23. doi: 10.1007/s40264-023-01379-0. Online ahead of print. ABSTRACT INTRODUCTION: Published data on the safety of natural medical cannabis (MC) when used...
CB1R dysfunction of inhibitory synapses in the ACC drives chronic social isolation stress-induced social impairments in male mice
Neuron. 2023 Nov 15:S0896-6273(23)00808-5. doi: 10.1016/j.neuron.2023.10.027. Online ahead of print. ABSTRACT Social isolation is a risk factor for multiple mood disorders. Specifically, social isolation can...
Cannabidiol protects the liver from α-Amanitin-induced apoptosis and oxidative stress through the regulation of Nrf2
Food Chem Toxicol. 2023 Nov 20:114196. doi: 10.1016/j.fct.2023.114196. Online ahead of print. ABSTRACT α-Amanitin, the primary lethal toxin of Amanita, specifically targets the liver, causing...
Sex differences in the association between plasma polyunsaturated fatty acids levels and moderate-to-severe plaque psoriasis severity: a cross-sectional and longitudinal study
J Transl Med. 2023 Nov 20;21(1):834. doi: 10.1186/s12967-023-04726-y. ABSTRACT BACKGROUND: Psoriasis is a chronic inflammatory skin disease with metabolic abnormalities serving as important contributors for...
Metabolic fate of DHA from regio- and stereospecific positions of triacylglycerols in a long-term feeding trial in rats
Food Res Int. 2023 Dec;174(Pt 1):113626. doi: 10.1016/j.foodres.2023.113626. Epub 2023 Oct 25. ABSTRACT This study investigated the impact of regio- and stereospecific position of docosahexaenoic...
Effect of edible oil type on the formation of protein-bound Nε-(carboxymethyl)lysine in roasted pork patties
Food Res Int. 2023 Dec;174(Pt 1):113628. doi: 10.1016/j.foodres.2023.113628. Epub 2023 Oct 25. ABSTRACT Protein-bound Nε-(carboxymethyl)lysine (CML), an advanced glycation end product within meat products, poses...
Descriptive cross-sectional survey of tobacco and cannabis restrictions on state and local film incentives in the USA
Tob Control. 2023 Nov 21:tc-2023-058197. doi: 10.1136/tc-2023-058197. Online ahead of print. ABSTRACT BACKGROUND: Reducing tobacco depictions in media has significant health benefits because tobacco placements...