GPR55 inhibits the pro-adipogenic activity of anandamide in human adipose stromal cells
Exp Cell Res. 2023 Dec 30:113908. doi: 10.1016/j.yexcr.2023.113908. Online ahead of print. ABSTRACT The endocannabinoid anandamide (AEA) stimulates adipogenesis via the cannabinoid receptor CB1 in...
Identification, characterization, and molecular docking of immunomodulatory oligopeptides from bioavailable hempseed protein hydrolysates
Food Res Int. 2024 Jan;176:113712. doi: 10.1016/j.foodres.2023.113712. Epub 2023 Nov 29. ABSTRACT Promoting dietary patterns in which the content of vegetables is higher than the...
A study into the nature and extent of polydrug use in driving recidivism behavior
Traffic Inj Prev. 2024;25(2):110-115. doi: 10.1080/15389588.2023.2274273. Epub 2024 Jan 2. ABSTRACT OBJECTIVE: Polydrug use has become a frequent pattern of drug consumption in Europe, and...
Inhaled Litsea glaucescens K. (Lauraceae) leaves’ essential oil has anxiolytic and antidepressant-like activity in mice by BDNF pathway activation
J Ethnopharmacol. 2024 Mar 1;321:117489. doi: 10.1016/j.jep.2023.117489. Epub 2023 Nov 25. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Litsea glaucescens K. (Lauraceae) is a small tree from the Mexican...
Impact of various high fat diets on gene expression and the microbiome across the mouse intestines
Sci Rep. 2023 Dec 27;13(1):22758. doi: 10.1038/s41598-023-49555-7. ABSTRACT High fat diets (HFDs) have been linked to several diseases including obesity, diabetes, fatty liver, inflammatory bowel...
Synthetic polyploid induction influences morphological, physiological, and photosynthetic characteristics in Melissa officinalis L
Front Plant Sci. 2023 Dec 14;14:1332428. doi: 10.3389/fpls.2023.1332428. eCollection 2023. ABSTRACT Melissa officinalis L., a well-known herb with diverse industrial and ethnopharmacological properties. Although, there...
A cohort study comparing the effects of medical cannabis for anxiety patients with and without comorbid sleep disturbance
Neuropsychopharmacol Rep. 2023 Dec 28. doi: 10.1002/npr2.12407. Online ahead of print. ABSTRACT BACKGROUND: Research on cannabis-based medicinal products (CBMPs) in anxiety remains inconclusive due to...
The consumption of psychoactive substances among French physicians: how do they perceive the creation of a dedicated healthcare system?
Front Psychiatry. 2023 Dec 14;14:1249434. doi: 10.3389/fpsyt.2023.1249434. eCollection 2023. ABSTRACT INTRODUCTION: Substance use among physicians can have negative impacts on their health, quality of life,...
Investigation of the effect of carnitine on cerebral vasospasm in experimental subarachnoid hemorrhage model
Sci Rep. 2023 Dec 27;13(1):23033. doi: 10.1038/s41598-023-50025-3. ABSTRACT The vasospasm, which develops after subarachnoid hemorrhage (SAH), is an unenlightened table in terms of etiology and...
Trajectory modeling of cannabis use over 30 years identifies five unique longitudinal patterns
Sci Rep. 2023 Dec 27;13(1):23070. doi: 10.1038/s41598-023-50376-x. ABSTRACT Cannabis is the most prevalently used psychoactive substance in the United States. Cannabis has conflicting federal and...
High-Cost and High-Dose Prescriptions of Cannabis-Based Medicines
Dtsch Arztebl Int. 2023 Nov 24;120(47):813-814. doi: 10.3238/arztebl.m2023.0201. NO ABSTRACT PMID:38154052 | DOI:10.3238/arztebl.m2023.0201...
Labor trafficking in marijuana production: a hidden epidemic in the shadows of the cannabis industry
Front Sociol. 2023 Dec 12;8:1244579. doi: 10.3389/fsoc.2023.1244579. eCollection 2023. ABSTRACT Labor trafficking in marijuana production remains a concealed epidemic within the expanding cannabis industry. This...
Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
Eur J Med Chem. 2023 Dec 14;265:116048. doi: 10.1016/j.ejmech.2023.116048. Online ahead of print. ABSTRACT Cannabinoid CB2R agonists have gained considerable attention as potential novel therapies...
Cannabis Sativa targets mediobasal hypothalamic neurons to stimulate appetite
Sci Rep. 2023 Dec 27;13(1):22970. doi: 10.1038/s41598-023-50112-5. ABSTRACT The neurobiological mechanisms that regulate the appetite-stimulatory properties of cannabis sativa are unresolved. This work examined the...
Endocannabinoid system in the paraventricular nucleus of the hypothalamus modulates autonomic and cardiovascular changes but not vasopressin response in a rat hemorrhagic shock model
Shock. 2023 Dec 12. doi: 10.1097/SHK.0000000000002286. Online ahead of print. ABSTRACT We evaluated the participation of the endocannabinoid system in the paraventricular nucleus of the...