Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults with ADPKD
Clin J Am Soc Nephrol. 2021 Dec 14:CJN.08950621. doi: 10.2215/CJN.08950621. Online ahead of print. ABSTRACT Background and Objectives: Clinical manifestations of autosomal dominant polycystic kidney...
An open label, single arm, prospective clinical study to evaluate liver safety and tolerability of PUREMERIC™ (standardized extract from Curcuma longa) in healthy subjects
Toxicol Rep. 2021 Nov 30;8:1955-1959. doi: 10.1016/j.toxrep.2021.11.022. eCollection 2021. ABSTRACT OBJECTIVE: Turmeric is a culinary spice valued since ancient time for its medicinal properties, mostly...
A Curcumin Analog Reduces Levels of the Alzheimer’s Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy
J Alzheimers Dis. 2019;72(3):761-771. doi: 10.3233/JAD-190562. ABSTRACT Alzheimer’s disease (AD) is a devastating neurodegenerative disease with no cure currently available. A pathological hallmark of AD...
The Acute and Chronic Cognitive and Cerebral Blood-Flow Effects of Nepalese Pepper (Zanthoxylum armatum DC.) Extract-A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Humans
Nutrients. 2019 Dec 10;11(12):3022. doi: 10.3390/nu11123022. ABSTRACT Background: Zanthoxylum armatum DC. (ZA) is a traditional Asian culinary spice and medicinal compound, which is rich in...
Chemical profile, traditional uses, and biological activities of Piper chaba Hunter: A review
J Ethnopharmacol. 2020 Jul 15;257:112853. doi: 10.1016/j.jep.2020.112853. Epub 2020 Apr 10. ABSTRACT ETHNOPHARMACOLOGICAL RELEVANCE: Piper chaba Hunter, called Chui Jhal or Choi Jhal, is commonly...
Protective effects of Cinnamomum verum, Cinnamomum cassia and cinnamaldehyde against 6-OHDA-induced apoptosis in PC12 cells
Mol Biol Rep. 2020 Apr;47(4):2437-2445. doi: 10.1007/s11033-020-05284-y. Epub 2020 Mar 12. ABSTRACT Cinnamon (Cinnamomum verum and C. cassia) is a medicinal plant, widely-used as a...
Metabolite profiling by means of GC-MS combined with principal component analyses of natural populations of Nectaroscordum siculum ssp. bulgaricum (Janka) Stearn
Z Naturforsch C J Biosci. 2020 Nov 26;75(11-12):451-457. doi: 10.1515/znc-2020-0058. ABSTRACT Nectaroscordum siculum ssp. bulgaricum (Janka) Stearn (Allium siculum subsp. dioscoridis (Sm.) K. Richt.) is...
Effects of garlic powder and salt additions on fatty acids profile, oxidative status, antioxidant potential and sensory properties of raw and cooked rabbit meat burgers
Meat Sci. 2020 Nov;169:108226. doi: 10.1016/j.meatsci.2020.108226. Epub 2020 Jun 19. ABSTRACT Rabbit burgers were evaluated for fatty acids profile, oxidative status, antioxidant potential and sensory...
Culinary spice bioactives as potential therapeutics against SARS-CoV-2: Computational investigation
Comput Biol Med. 2021 Jan;128:104102. doi: 10.1016/j.compbiomed.2020.104102. Epub 2020 Nov 3. ABSTRACT BACKGROUND: Coronavirus disease-2019 (COVID-19) is an infectious pandemic caused by SARS-CoV-2. SARS-CoV-2 main...
Molecular Basis of the Therapeutical Potential of Clove (Syzygium aromaticum L.) and Clues to Its Anti-COVID-19 Utility
Molecules. 2021 Mar 26;26(7):1880. doi: 10.3390/molecules26071880. ABSTRACT The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and...
Anti-Inflammatory Potential Exhibited by Amomum subulatum Fruits Mitigates Experimentally Induced Acute and Chronic Inflammation in Mice: Evaluation of Antioxidant Parameters, Pro-Inflammatory Mediators and HO-1 Pathway
J Am Coll Nutr. 2021 Aug;40(6):551-561. doi: 10.1080/07315724.2020.1806139. Epub 2021 Jan 5. ABSTRACT OBJECTIVE: Conventional anti-inflammatory drugs are associated with serious adverse effects which bring...
Comparison of various commercially available cinnamon barks using NMR metabolomics and the quantification of coumarin by quantitative NMR methods
J Nat Med. 2021 Aug 6. doi: 10.1007/s11418-021-01554-6. Online ahead of print. ABSTRACT Cinnamon bark is an important spice worldwide. In this study, the chemical...
Antioxidant-rich fraction of Amomum subulatum fruits mitigates experimental methotrexate-induced oxidative stress by regulating TNF-α, IL-1β, and IL-6 proinflammatory cytokines
J Food Biochem. 2021 Jul 11:e13855. doi: 10.1111/jfbc.13855. Online ahead of print. ABSTRACT The culinary spice Amomum subulatum was assessed for its phytochemical composition, in...
Linking the antimicrobial and anti-inflammatory effects of immortelle essential oil with its chemical composition – The interplay between the major and minor constituents
Food Chem Toxicol. 2021 Dec;158:112666. doi: 10.1016/j.fct.2021.112666. Epub 2021 Nov 9. ABSTRACT Immortelle (Helichrysum italicum, Asteraceae) essential oil has been widely used in alternative medicine...
Antioxidant-rich Clove Extract, A Strong Antimicrobial Agent against Urinary Tract Infections-causing Bacteria in vitro
Trop Life Sci Res. 2021 Jun;32(2):45-63. doi: 10.21315/tlsr2021.32.2.4. Epub 2021 Jun 29. ABSTRACT Clove (Syzygium aromaticum) is an exotic culinary spice that has been used...