Using the derived 28-joint disease activity score patient-reported components (DAS28-P) index as a discriminatory measure of response to disease-modifying anti-rheumatic drug therapy in early rheumatoid arthritis
BMC Rheumatol. 2022 Nov 15;6(1):67. doi: 10.1186/s41927-022-00299-3. ABSTRACT BACKGROUND: The 28-joint disease activity score (DAS28) is a widely used measure to assess disease activity in...
Improved Oxygen Uptake Efficiency Parameters Are Not Correlated with VO2peak or Running Economy and Are Not Affected by Omega-3 Fatty Acid Supplementation in Endurance Runners
Int J Environ Res Public Health. 2022 Oct 28;19(21):14043. doi: 10.3390/ijerph192114043. ABSTRACT Peak oxygen uptake (VO2peak) is one of the most reliable parameters of exercise...
Comparative Analysis of Docosahexaenoic Acid (DHA) Content in Mother’s Milk of Term and Preterm Mothers
Nutrients. 2022 Nov 1;14(21):4595. doi: 10.3390/nu14214595. ABSTRACT OBJECTIVES AND STUDY: Docosahexaenoic acid (DHA) plays an essential role in infants’ development. Maternal diet and breastmilk are...
Topical Omega-3 Fatty Acids Eyedrops in the Treatment of Dry Eye and Ocular Surface Disease: A Systematic Review
Int J Mol Sci. 2022 Oct 29;23(21):13156. doi: 10.3390/ijms232113156. ABSTRACT Dry eye is a common inflammatory condition of the ocular surface. While oral omega-3 supplementation...
Methotrexate-Induced Alteration of Renal Aquaporins 1 and 2, Oxidative Stress and Tubular Apoptosis Can Be Attenuated by Omega-3 Fatty Acids Supplementation
Int J Mol Sci. 2022 Oct 24;23(21):12794. doi: 10.3390/ijms232112794. ABSTRACT Methotrexate (MTX) is a potent anti-cancer drug, commonly associated with nephrotoxicity via the induction of...
Association of Polyunsaturated Fatty Acid Intake on Inflammatory Gene Expression and Multiple Sclerosis: A Systematic Review and Meta-Analysis
Nutrients. 2022 Nov 2;14(21):4627. doi: 10.3390/nu14214627. ABSTRACT The health benefits of omega-3 fatty acid (FA) supplementation on inflammatory gene expression (IGE) and multiple sclerosis (MS)...
Oxylipins Associated with D3-Creatine Muscle Mass/Weight and Physical Performance among Community-Dwelling Older Men
Int J Mol Sci. 2022 Oct 25;23(21):12857. doi: 10.3390/ijms232112857. ABSTRACT Poor physical function is highly prevalent with aging, and strongly associated with D3-creatine muscle mass/weight....
Short-Term Omega-3 Supplementation Modulates Novel Neurovascular and Fatty Acid Metabolic Proteome Changes in the Retina and Ophthalmic Artery of Mice with Targeted Cyp2c44 Gene Deletion
Cells. 2022 Nov 4;11(21):3494. doi: 10.3390/cells11213494. ABSTRACT Cytochrome P450 (CYP) gene mutations are a common predisposition associated with glaucoma. Although the molecular mechanisms are largely...
Dietary fish oil increases catalase activity in patients with probable Alzheimer’s disease
Nutr Hosp. 2022 Nov 3. doi: 10.20960/nh.04153. Online ahead of print. ABSTRACT BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the presence of...
Impact of Vitamin D3 Versus Placebo on Cardiac Structure and Function: A Randomized Clinical Trial
J Am Heart Assoc. 2022 Nov;11(21):e025008. doi: 10.1161/JAHA.121.025008. Epub 2022 Oct 26. ABSTRACT Background Vitamin D supplementation leads to regression of left ventricular (LV) hypertrophy...
Cost-effectiveness analysis of adding omega-3 or vitamin D supplementation to standard therapy in treating painful crises of pediatric sickle cell disease patients
Eur Rev Med Pharmacol Sci. 2022 Oct;26(20):7506-7513. doi: 10.26355/eurrev_202210_30021. ABSTRACT OBJECTIVE: Painful crises represents a predominant complication of sickle cell disease (SCD). The only approved...
Neonatal Docosahexaenoic Acid in Preterm Infants and Intelligence at 5 Years
N Engl J Med. 2022 Oct 27;387(17):1579-1588. doi: 10.1056/NEJMoa2206868. ABSTRACT BACKGROUND: Docosahexaenoic acid (DHA) is a component of neural tissue. Because its accretion into the...
Increased efficacy of dietary supplement containing wax ester-rich marine oil and xanthophylls in a mouse model of dry macular degeneration
Front Pharmacol. 2022 Oct 13;13:1038730. doi: 10.3389/fphar.2022.1038730. eCollection 2022. ABSTRACT Age-related macular degeneration (AMD) is nowadays considered among the retinal diseases whose clinical management lacks...
Mechanistic insights into the health benefits of fish-oil supplementation against fine particulate matter air pollution: a randomized controlled trial
Environ Health. 2022 Oct 29;21(1):104. doi: 10.1186/s12940-022-00908-1. ABSTRACT BACKGROUND: Dietary fish-oil supplementation might attenuate the associations between fine particulate matter (PM2.5) and subclinical biomarkers. However,...
Habitual fish oil supplementation and incident chronic obstructive pulmonary disease: Data from a prospective cohort study
Clin Nutr. 2022 Oct 8;41(12):2651-2658. doi: 10.1016/j.clnu.2022.10.002. Online ahead of print. ABSTRACT BACKGROUND: Fish oil is one of the most popular supplements in the UK...