Ultra-High-Performance Liquid Chromatography Coupled with Quadrupole Orbitrap High-Resolution Mass Spectrometry for Multi-Residue Analysis of Mycotoxins and Pesticides in Botanical Nutraceuticals
Toxins (Basel). 2020 Feb 12;12(2):114. doi: 10.3390/toxins12020114. ABSTRACT Cannabidiol (CBD) food supplements made of Cannabis sativa L. extracts have quickly become popular products due to...
Severe Vitamin K-dependent Coagulopathy from Rodenticide-contaminated Synthetic Cannabinoids: Emergency Department Presentations
West J Emerg Med. 2021 Jul 15;22(4):1014-1019. doi: 10.5811/westjem.2021.2.46317. ABSTRACT INTRODUCTION: Synthetic cannabinoids are a rapidly expanding subset of designer drugs widely available in the...
Toxicological aspects of cannabinoid, pesticide and metal levels detected in light Cannabis inflorescences grown in Italy
Food Chem Toxicol. 2021 Oct;156:112447. doi: 10.1016/j.fct.2021.112447. Epub 2021 Jul 31. ABSTRACT Recently, the cultivation of light Cannabis, with a total THC content less than...
Analysis of the California list of pesticides, mycotoxins, and cannabinoids in chocolate using liquid chromatography and low-pressure gas chromatography-based platforms
J Sep Sci. 2021 Jul;44(13):2564-2576. doi: 10.1002/jssc.202001265. Epub 2021 May 24. ABSTRACT Cannabis legalization has led to the development of a variety of cannabis-infused products...
Combined Toxicity of Cannabidiol Oil with Three Bio-Pesticides against Adults of Sitophilus Zeamais, Rhyzopertha Dominica, Prostephanus Truncatus and Trogoderma Granarium
Int J Environ Res Public Health. 2020 Sep 13;17(18):6664. doi: 10.3390/ijerph17186664. ABSTRACT The present study investigates the interaction between cannabidiol (CBD) oil and three biopesticides:...
Brodifacoum Poisoning Linked to Synthetic Marijuana Use in Wisconsin
WMJ. 2020 Jun;119(2):129-131. ABSTRACT INTRODUCTION: Recent outbreaks of brodifacoum-induced coagulopathy resulting from the use of synthetic cannabinoids represents a growing public health concern. Brodifacoum is...
Clinical Pharmacists: Essential During a Poison Outbreak
J Med Toxicol. 2020 Oct;16(4):356-357. doi: 10.1007/s13181-020-00793-5. Epub 2020 Jul 7. NO ABSTRACT PMID:32638283 | PMC:PMC7554288 | DOI:10.1007/s13181-020-00793-5...
Selective isolation of pesticides and cannabinoids using polymeric ionic liquid-based sorbent coatings in solid-phase microextraction coupled to high-performance liquid chromatography
J Chromatogr A. 2022 Sep 13;1680:463416. doi: 10.1016/j.chroma.2022.463416. Epub 2022 Aug 10. ABSTRACT The high abundance of cannabinoids within cannabis samples presents an issue for...
Beyond Pain Relief: A Review on Cannabidiol Potential in Medical Therapies
Pharmaceuticals (Basel). 2023 Jan 20;16(2):155. doi: 10.3390/ph16020155. ABSTRACT The phytocannabinoid cannabidiol (CBD) is receiving increasing attention due to its pharmacological properties. Although CBD is extracted...
Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo
Front Synaptic Neurosci. 2023 May 12;15:1176864. doi: 10.3389/fnsyn.2023.1176864. eCollection 2023. ABSTRACT Cannabis exposure during gestation evokes significant molecular modifications to neurodevelopmental programs leading to neurophysiological...
Role of omega-3 and omega-6 endocannabinoids in cardiopulmonary pharmacology
Adv Pharmacol. 2023;97:375-422. doi: 10.1016/bs.apha.2023.02.003. Epub 2023 Mar 28. ABSTRACT Endocannabinoids are derived from dietary omega-3 and omega-6 fatty acids and play an important role...
Cannabinoid and Opioid Receptor Affinity and Modulation of Cancer-Related Signaling Pathways of Machaeriols and Machaeridiols from Machaerium Pers
Molecules. 2023 May 18;28(10):4162. doi: 10.3390/molecules28104162. ABSTRACT Machaeriols and machaeridiols are unique hexahydrodibenzopyran-type aralkyl phytocannabinoids isolated from Machaerium Pers. Earlier studies of machaeriol A (1)...
Non-Psychoactive Cannabinoid Modulation of Nociception and Inflammation Associated with a Rat Model of Pulpitis
Biomolecules. 2023 May 16;13(5):846. doi: 10.3390/biom13050846. ABSTRACT Despite advancements in dental pain management, one of the most common reasons for emergency dental care is orofacial...
Bioactivity of the cannabigerol cannabinoid and its analogues – the role of 3-dimensional conformation
Org Biomol Chem. 2023 May 24. doi: 10.1039/d3ob00383c. Online ahead of print. ABSTRACT Cannabinoids are naturally occurring bioactive compounds with the potential to help treat...
Cannabidiol inhibits neuroinflammatory responses and circuit-associated synaptic loss following damage to a songbird vocal pre-motor cortical-like region
Sci Rep. 2023 May 16;13(1):7907. doi: 10.1038/s41598-023-34924-z. ABSTRACT The non-euphorigenic phytocannabinoid cannabidiol (CBD) has been used successfully to treat childhood-onset epilepsies. These conditions are associated...