Immunoreactivity of acetylcholinesterase and M1 muscarinic receptors in the hippocampus and striatum of rats treated with Rebaudioside A
Pol J Vet Sci. 2022 Jun;25(2):303-310. doi: 10.24425/pjvs.2022.141815. ABSTRACT Rebaudioside A (RebA) is a steviol glycoside used for production of sweeteners. It was shown that...
Prevention of Bortezomib-Induced Peripheral Neuropathy in Newly Multiple Myeloma Patients Using Nervonic Acid, Curcuma Rizoma, and L-Arginine Compound: A Pilot Study
Integr Cancer Ther. 2022 Jan-Dec;21:15347354221114142. doi: 10.1177/15347354221114142. ABSTRACT INTRODUCTION: This is a phase II pilot study to evaluate the efficacy of a nutraceutical compound composed...
Neuroprotective Effects of Curcumin against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Cultured Primary Rat Astrocyte by Improving Mitochondrial Function and Regulating the ERK Signaling Pathway
Evid Based Complement Alternat Med. 2022 Jul 12;2022:1731701. doi: 10.1155/2022/1731701. eCollection 2022. ABSTRACT OBJECTIVES: Curcumin (Cur) is a natural polyphenol isolated from turmeric and has...
Prevention of Bortezomib-Induced Peripheral Neuropathy in Newly Multiple Myeloma Patients Using Nervonic Acid, Curcuma Rizoma, and L-Arginine Compound: A Pilot Study
Integr Cancer Ther. 2022 Jan-Dec;21:15347354221114142. doi: 10.1177/15347354221114142. ABSTRACT INTRODUCTION: This is a phase II pilot study to evaluate the efficacy of a nutraceutical compound composed...
Proteomics reveals the key molecules involved in curcumin-induced protection against sciatic nerve injury in rats
Neuroscience. 2022 Jul 20:S0306-4522(22)00232-9. doi: 10.1016/j.neuroscience.2022.05.003. Online ahead of print. ABSTRACT We generated a rat model of sciatic nerve crush injury and characterized the effects...
Quercetin as a JAK-STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases
Cell Mol Biol Lett. 2022 Jul 26;27(1):60. doi: 10.1186/s11658-022-00355-3. ABSTRACT The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway is involved in many immunological...
Protective Effects of Diets Rich in Polyphenols in Cigarette Smoke (CS)-Induced Oxidative Damages and Associated Health Implications
Antioxidants (Basel). 2022 Jun 21;11(7):1217. doi: 10.3390/antiox11071217. ABSTRACT Cigarette smoking has been responsible for causing many life-threatening diseases such as pulmonary and cardiovascular diseases as...
Role of Inflammation, Oxidative Stress, and Mitochondrial Changes in Premenstrual Psychosomatic Behavioral Symptoms with Anti-Inflammatory, Antioxidant Herbs, and Nutritional Supplements
Oxid Med Cell Longev. 2022 Jul 13;2022:3599246. doi: 10.1155/2022/3599246. eCollection 2022. ABSTRACT Premenstrual syndrome (PMS) significantly lowers the quality of life and impairs personal and...
Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations
Front Aging. 2022 Jul 12;3:931331. doi: 10.3389/fragi.2022.931331. eCollection 2022. ABSTRACT The α-Klotho protein (henceforth denoted Klotho) has antiaging properties, as first observed in mice homozygous...
Quercetin Promotes TFEB Nuclear Translocation and Activates Lysosomal Degradation of Ferritin to Induce Ferroptosis in Breast Cancer Cells
Comput Intell Neurosci. 2022 Jul 18;2022:5299218. doi: 10.1155/2022/5299218. eCollection 2022. ABSTRACT Objective. To investigate the antiproliferative efficacy of quercetin on breast cell lines and its...
Curcumin Regulates Anti-Inflammatory Responses by AXL/JAK2/STAT3 Signaling Pathway in experimental autoimmune encephalomyelitis
Neurosci Lett. 2022 Jul 28:136821. doi: 10.1016/j.neulet.2022.136821. Online ahead of print. ABSTRACT Microglia-mediated neuroinflammation plays an important role in multiple sclerosis (MS). This study explored...
Prospects for the use of polyphenols in multiple sclerosis
Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(7. Vyp. 2):36-43. doi: 10.17116/jnevro202212207236. ABSTRACT Multiple sclerosis (MS) is a chronic demyelinating autoimmune disease. Therapy for MS...
A novel multi-target strategy for Alzheimer’s disease treatment via sublingual route: Donepezil/memantine/curcumin-loaded nanofibers
Biomater Adv. 2022 Jul;138:212870. doi: 10.1016/j.bioadv.2022.212870. Epub 2022 May 18. ABSTRACT Drug delivery systems that not only show efficacy through multiple therapeutic pathways but also...
The action of curcumin against damage resulting from cerebral stroke: a systematic review
Pharmacol Res. 2022 Jul 29:106369. doi: 10.1016/j.phrs.2022.106369. Online ahead of print. ABSTRACT Stroke is the second leading cause of morbidity and mortality globally. Treatments for...
A Review of In Silico Research, SARS-CoV-2, and Neurodegeneration: Focus on Papain-Like Protease
Neurotox Res. 2022 Aug 2. doi: 10.1007/s12640-022-00542-2. Online ahead of print. ABSTRACT Since the appearance of SARS-CoV-2 and the COVID-19 pandemic, the search for new...