Targeting the Pathological Hallmarks of Alzheimer’s Disease Through Nanovesicle-aided Drug Delivery Approach
Curr Drug Metab. 2022 May 26. doi: 10.2174/1389200223666220526094802. Online ahead of print. ABSTRACT Introduction- Nanovesicle technology is making a huge contribution to the progress of...
Neuroprotective Effects of Cranberry Juice Treatment in a Rat Model of Parkinson’s Disease
Nutrients. 2022 May 11;14(10):2014. doi: 10.3390/nu14102014. ABSTRACT Rich in polyphenols, cranberry juice (CJ) with high antioxidant activity is believed to contribute to various health benefits....
Evaluation of curcumin as add-on therapy in patients with Parkinson’s disease: A pilot randomized, triple-blind, placebo-controlled trial
Clin Neurol Neurosurg. 2022 May 18;218:107300. doi: 10.1016/j.clineuro.2022.107300. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Preclinical studies suggest that curcumin might be a potential...
Protective effects of L-arginine on cognitive deficits and biochemical parameters in an experimental model of type-2 diabetes mellitus induced Alzheimer’s disease in rats
J Physiol Pharmacol. 2022 Feb;73(1). doi: 10.26402/jpp.2022.1.01. Epub 2022 May 27. ABSTRACT Alzheimer’s disease (AD) has been closely linked to type 2 diabetes mellitus (T2DM)...
Curcumin-loaded human endometrial stem cells derived exosomes as an effective carrier to suppress alpha-synuclein aggregates in 6OHDA-induced Parkinson’s disease mouse model
Cell Tissue Bank. 2022 Jun 1. doi: 10.1007/s10561-022-10008-6. Online ahead of print. ABSTRACT Parkinson disease (PD) is considered as one of the most worldwide neurodegenerative...
Curcumin mitigates lipopolysaccharide-induced anxiety/depression-like behaviors, blood-brain barrier dysfunction and brain edema by decreasing cerebral oxidative stress in male rats
Neurosci Lett. 2022 May 26;782:136697. doi: 10.1016/j.neulet.2022.136697. Online ahead of print. ABSTRACT Oxidative stress is a well-known risk factor for the development of anxiety and...
Natural Therapeutics in Aid of Treating Alzheimer’s Disease: A Green Gateway Toward Ending Quest for Treating Neurological Disorders
Front Neurosci. 2022 May 16;16:884345. doi: 10.3389/fnins.2022.884345. eCollection 2022. ABSTRACT The current scientific community is facing a daunting challenge to unravel reliable natural compounds with...
Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line
PLoS One. 2022 Jun 3;17(6):e0267682. doi: 10.1371/journal.pone.0267682. eCollection 2022. ABSTRACT Evaluating novel compounds for neuroprotective effects in animal models of traumatic brain injury (TBI) is...
Chronic Consumption of Cranberries (Vaccinium macrocarpon) for 12 Weeks Improves Episodic Memory and Regional Brain Perfusion in Healthy Older Adults: A Randomised, Placebo-Controlled, Parallel-Groups Feasibility Study
Front Nutr. 2022 May 19;9:849902. doi: 10.3389/fnut.2022.849902. eCollection 2022. ABSTRACT BACKGROUND: Ageing is highly associated with cognitive decline and modifiable risk factors such as diet...
Role of Curcumin in the Management of Schizophrenia: A Narrative Review
Indian J Psychol Med. 2022 Mar;44(2):107-113. doi: 10.1177/02537176211033331. Epub 2021 Sep 13. ABSTRACT Nutraceutical agents and food supplements are commonly used as treatment adjuncts in...
Neuroprotective Effects of Quercetin on Ischemic Stroke: A Literature Review
Front Pharmacol. 2022 May 18;13:854249. doi: 10.3389/fphar.2022.854249. eCollection 2022. ABSTRACT Ischemic stroke (IS) is characterized by high recurrence and disability; however, its therapies are very...
A comprehensive review on modulation of SIRT1 signaling pathways in the immune system of COVID-19 patients by phytotherapeutic melatonin and epigallocatechin-3-gallate
J Food Biochem. 2022 Jun 3:e14259. doi: 10.1111/jfbc.14259. Online ahead of print. ABSTRACT SARS-CoV-2 infection has now become the world’s most significant health hazard, with...
Phloroglucinol, a clinical-used antispasmodic, inhibits amyloid aggregation and degrades the pre-formed amyloid proteins
Int J Biol Macromol. 2022 Jun 3:S0141-8130(22)01202-8. doi: 10.1016/j.ijbiomac.2022.06.008. Online ahead of print. ABSTRACT Amyloid proteins, such as β-amyloid (Aβ) and α-synuclein (α-syn), could form...
Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway
Front Neurol. 2022 May 20;13:905640. doi: 10.3389/fneur.2022.905640. eCollection 2022. ABSTRACT The pathogenesis of spinal cord injury (SCI) is complex. At present, there is no effective...
Neuroprotective potential of curcuminoids in modulating Alzheimer’s Disease via multiple signaling pathways
Curr Med Chem. 2022 Jun 7. doi: 10.2174/0929867329666220607161328. Online ahead of print. ABSTRACT Alzheimer’s disease (AD) is a progressive and frequent neurodegenerative disease of elderly...