Absorption, Distribution, Metabolism, and Excretion of the Main Olive Tree Phenols and Polyphenols: A Literature Review
J Agric Food Chem. 2021 May 12;69(18):5281-5296. doi: 10.1021/acs.jafc.1c00737. Epub 2021 Apr 28. ABSTRACT The effects of olive tree (poly)phenols (OPs) are largely dependent upon...
Olive oil and oleic acid-based self nano-emulsifying formulation of omega-3-fatty acids with improved strength, stability, and therapeutics
J Microencapsul. 2021 Aug;38(5):298-313. doi: 10.1080/02652048.2021.1914760. Epub 2021 May 17. ABSTRACT AIM: To develop, characterise, and optimise SNEDDS formulation to enhance organoleptics, bioavailability, physical &...
Impact of excipient emulsions made from different types of oils on the bioavailability and metabolism of curcumin in gastrointestinal tract
Food Chem. 2022 Feb 15;370:130980. doi: 10.1016/j.foodchem.2021.130980. Epub 2021 Aug 30. ABSTRACT Low bioavailability currently limits the potential of curcumin as a health-promoting dietary compound....
Maximizing the Oral Bioavailability of Poorly Water-Soluble Drugs Using Novel Oil-Like Materials in Lipid-Based Formulations
Mol Pharm. 2021 Sep 6;18(9):3281-3289. doi: 10.1021/acs.molpharmaceut.1c00197. Epub 2021 Aug 5. ABSTRACT Lipid-based formulations, such as self-microemulsifying drug-delivery systems (SMEDDSs), are promising tools for the...
Medium Chain Triglycerides Promote the Uptake of β-Carotene in O/W Emulsions via Intestinal Transporter SR-B1 in Caco-2 Cells
J Agric Food Chem. 2022 Aug 3;70(30):9377-9387. doi: 10.1021/acs.jafc.2c02660. Epub 2022 Jul 21. ABSTRACT This study aimed to elucidate the impacts of carrier oil types...
Effect of Gum Acacia on the Intestinal Bioavailability of n-3 Polyunsaturated Fatty Acids in Rats
Biomolecules. 2022 Jul 12;12(7):975. doi: 10.3390/biom12070975. ABSTRACT Lipid emulsification is a technique that is being explored for improving the bioavailability of omega 3 (n-3) long...
Curcumin and Quercetin-Loaded Lipid Nanocarriers: Development of Omega-3 Mucoadhesive Nanoemulsions for Intranasal Administration
Nanomaterials (Basel). 2022 Mar 25;12(7):1073. doi: 10.3390/nano12071073. ABSTRACT Curcumin (CUR) and quercetin (QU) are potential compounds for treatment of brain diseases such as neurodegenerative diseases...
L-arginine in Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes: A Systematic Review
Neurology. 2022 Apr 15:10.1212/WNL.0000000000200299. doi: 10.1212/WNL.0000000000200299. Online ahead of print. ABSTRACT OBJECTIVE: Stroke management in the context of primary mitochondrial disease is clinically challenging and...
Coumarin derivatives as inhibitors of d-amino acid oxidase and monoamine oxidase
Bioorg Chem. 2022 Apr 6;123:105791. doi: 10.1016/j.bioorg.2022.105791. Online ahead of print. ABSTRACT d-Amino acid oxidase (DAAO) oxidises d-amino acids to ultimately produce the corresponding α-keto...
A novel process driving Alzheimer’s disease validated in a mouse model: Therapeutic potential
Alzheimers Dement (N Y). 2022 Apr 5;8(1):e12274. doi: 10.1002/trc2.12274. eCollection 2022. ABSTRACT INTRODUCTION: The neuronal mechanism driving Alzheimer’s disease (AD) is incompletely understood. METHODS: Immunohistochemistry,...
Application of Sol-Gels Modified with Natural Plants Extracts as Stationary Phases in Open-Tubular Capillary Electrochromatography
Gels. 2022 Mar 22;8(4):198. doi: 10.3390/gels8040198. ABSTRACT Ethanol extracts of three widely growing plants were added to silica sol-gel solutions, which were subsequently applied as...
Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update
Front Pharmacol. 2022 Apr 8;13:865376. doi: 10.3389/fphar.2022.865376. eCollection 2022. ABSTRACT Depression is a global health problem with growing prevalence rates and serious impacts on the...
Quercetin: an effective polyphenol in alleviating diabetes and diabetic complications
Crit Rev Food Sci Nutr. 2022 Apr 25:1-24. doi: 10.1080/10408398.2022.2067825. Online ahead of print. ABSTRACT Various studies, especially in recent years, have shown that quercetin...
Silymarin-Encapsulated Xanthan Gum-Stabilized Selenium Nanocarriers for Enhanced Activity Against Amyloid Fibril Cytotoxicity
AAPS PharmSciTech. 2022 Apr 26;23(5):125. doi: 10.1208/s12249-022-02274-0. ABSTRACT The accumulation of amyloid-beta at the neuronal sites is a major pathological hallmark involved in the etiology...
Therapeutic role of curcumin in adult neurogenesis for management of psychiatric and neurological disorders: a scientometric study to an in-depth review
Crit Rev Food Sci Nutr. 2022 Apr 28:1-13. doi: 10.1080/10408398.2022.2067827. Online ahead of print. ABSTRACT Aberrant neurogenesis is a major factor in psychiatric and neurological...