HomeIngredientPhysicochemical Properties, Antioxidant and Antimicrobial Activities of Ethiopian Sweet Basil (Ocimum basilicum L.) Leaf and Flower Oil Extracts

Physicochemical Properties, Antioxidant and Antimicrobial Activities of Ethiopian Sweet Basil (Ocimum basilicum L.) Leaf and Flower Oil Extracts

August 20, 2022

Recent Adv Antiinfect Drug Discov. 2022 Jul 20. doi: 10.2174/2772434417666220720121051. Online ahead of print.

ABSTRACT

The occurrence of multidrug resistant pathogenic microbes has initiated the development of natural antimicrobial agents from plants. Oils from herbal sources have drawn scientific interest due to their potential source of bioactive compounds. <P> Objective: This study was aimed to examine the physicochemical and biological activities including antioxidant and antimicrobial potential of the oil extracted from basil leaves and flowers. <P> Methods: The physicochemical properties of the oil extracts were measured based on oil yield, specific gravity, acid value, free fatty acids and peroxide values whilst the antioxidant activities were assessed by ascorbic acid, DPPH (2, 2- diphenyl-1-picrylhydrazyl), and hydrogen peroxide free radical scavenging activities. The antimicrobial experiment was conducted based on disc diffusion and broth dilution methods. <P> Results: The result of antioxidant activity of Ocimum basilicum indicated that significantly higher DPPH (86.45%) for leaf oil extract. The strongest antibacterial activity with maximum zone of inhibition (15.47mm), minimum inhibitory concentration MIC (0.09µg/ml), and corresponding minimum bactericidal concentration MBC (0.19 µg/ml) was exhibited by the flower oil extract against Staphylococcus aureus ATCC-25923. The strongest antifungal activity with maximum zone of inhibition (15.90mm), MIC (0.125µg/ml, the least value), and minimum fungicidal concentration MFC (0.09µg/ml) were recorded for leaf oil against Candida albicans. <p> Conclusion: It can be concluded from the present study that the sweet basil flower and leaf oil extracts can be potential antioxidant, antibacterial, and antifungal activity.

PMID:35864798 | DOI:10.2174/2772434417666220720121051

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Patrick Blanchard MD

Meet Dr. Blanchard Dr. Blanchard’s medical practice is an embodiment of Integrative health which brings conventional and complementary approaches together in a coordinated way. Conveniently located in sunny Florida and over the internet with ValiseMD’s secure HIPPA compliant telXmed servers. Since 1994, patients with a wide range of challenging medical problems have achieved optimum health using the best of natural medicine, judiciously combined with high-tech innovations. Breakthroughs are often achieved even after patients have consulted mainstream specialists and holistic practitioners. Dr. Blanchard is founder and CEO of ValiseMD, Inc. He is board certified in Family Medicine since 1994 and awarded Fellow of the American Academy of Family Physicians in 2001. He received the ‘Teacher of the Year’ award from the University of Kansas School of Medicine at completion of his residency in Family Medicine. He completed a fellowship at Wake Forest University in the field of vascular neurosonology. He holds a medical patent in the field of Gastroenterology. He holds an unrestricted license to practice medicine and surgery in Florida. He started his medical career as a Emergency Medical Technician, then as a Paramedic and later a Medical Doctor.