Longer Photoperiod Substantially Increases Indoor-Grown Cannabis’ Yield and Quality: A Study of Two High-THC Cultivars Grown under 12 h vs. 13 h Days
Plants (Basel). 2024 Feb 1;13(3):433. doi: 10.3390/plants13030433. ABSTRACT Indoor-grown Cannabis sativa is commonly transitioned to a 12 h daily photoperiod to promote flowering. However, our...
Targeting the Endocannabinoid System Present in the Glioblastoma Tumour Microenvironment as a Potential Anti-Cancer Strategy
Int J Mol Sci. 2024 Jan 23;25(3):1371. doi: 10.3390/ijms25031371. ABSTRACT The highly aggressive and invasive glioblastoma (GBM) tumour is the most malignant lesion among adult-type...
Neurobiology of Stress-Induced Nicotine Relapse
Int J Mol Sci. 2024 Jan 25;25(3):1482. doi: 10.3390/ijms25031482. ABSTRACT Tobacco smoking is the leading cause of preventable death and disease. Although there are some...
URB447 Is Neuroprotective in Both Male and Female Rats after Neonatal Hypoxia-Ischemia and Enhances Neurogenesis in Females
Int J Mol Sci. 2024 Jan 28;25(3):1607. doi: 10.3390/ijms25031607. ABSTRACT The need for new and effective treatments for neonates suffering from hypoxia-ischemia is urgent, as...
CB2 Cannabinoid Receptor as a Potential Target in Myocardial Infarction: Exploration of Molecular Pathogenesis and Therapeutic Strategies
Int J Mol Sci. 2024 Jan 30;25(3):1683. doi: 10.3390/ijms25031683. ABSTRACT The lipid endocannabinoid system has recently emerged as a novel therapeutic target for several inflammatory...
Joint CB1 and NGF Receptor Activation Suppresses TRPM8 Activation in Etoposide-Resistant Retinoblastoma Cells
Int J Mol Sci. 2024 Jan 31;25(3):1733. doi: 10.3390/ijms25031733. ABSTRACT In childhood, retinoblastoma (RB) is the most common primary tumor in the eye. Long term...
Cumulative Deleterious Effects of Tetrahydrocannabinoid (THC) and Ethanol on Mitochondrial Respiration and Reactive Oxygen Species Production Are Enhanced in Old Isolated Cardiac Mitochondria
Int J Mol Sci. 2024 Feb 2;25(3):1835. doi: 10.3390/ijms25031835. ABSTRACT Delta 9 tetrahydrocannabinol (THC), the main component of cannabis, has adverse effects on the cardiovascular...
Peripheral Endocannabinoid Components and Lipid Plasma Levels in Patients with Resistant Migraine and Co-Morbid Personality and Psychological Disorders: A Cross-Sectional Study
Int J Mol Sci. 2024 Feb 4;25(3):1893. doi: 10.3390/ijms25031893. ABSTRACT Resistant migraine characterizes those patients who have failed at least three classes of migraine prophylaxis....
G Protein-Coupled Receptors and Ion Channels Involvement in Cisplatin-Induced Peripheral Neuropathy: A Review of Preclinical Studies
Cancers (Basel). 2024 Jan 30;16(3):580. doi: 10.3390/cancers16030580. ABSTRACT Cisplatin is a platinum-based chemotherapy drug widely used to treat various solid tumours. Although it is effective...
Cannabis Use and Biomarkers of Inflammation, Immune Activation, and Microbial Translocation in Persons with HIV
Cannabis Cannabinoid Res. 2024 Feb 9. doi: 10.1089/can.2023.0109. Online ahead of print. ABSTRACT Background: The relationship between cannabis and inflammation among persons with HIV (PWH)...
Evaluating the Mechanism of Cell Death in Melanoma Induced by the Cannabis Extract PHEC-66
Cells. 2024 Jan 31;13(3):268. doi: 10.3390/cells13030268. ABSTRACT Research suggests the potential of using cannabinoid-derived compounds to function as anticancer agents against melanoma cells. Our recent...
Removing barriers to accessing medical cannabis for paediatric patients
Paediatr Child Health. 2023 Mar 31;29(1):12-16. doi: 10.1093/pch/pxac129. eCollection 2024 Feb. ABSTRACT Medical cannabis (MC) may offer therapeutic benefits for children with complex neurological conditions...
Serious and life-threatening events associated with non-medical cannabis use in Canadian children and youth
Paediatr Child Health. 2023 Jun 26;29(1):3-4. doi: 10.1093/pch/pxad036. eCollection 2024 Feb. NO ABSTRACT PMID:38332980 | PMC:PMC10848119 | DOI:10.1093/pch/pxad036...
Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells
Iran J Basic Med Sci. 2024;27(3):304-310. doi: 10.22038/IJBMS.2023.71819.15605. ABSTRACT OBJECTIVES: The process of vascular formation, also known as angiogenesis, primarily relies on endothelial cell proliferation,...
Oil-in-water and oleogel-in-water emulsion encapsulate with hemp seed oil containing Δ9-tetrahydrocannabinol and cannabinol: Stability, degradation and in vitro simulation characteristics
Food Chem. 2024 Feb 2;444:138633. doi: 10.1016/j.foodchem.2024.138633. Online ahead of print. ABSTRACT The present study focused on investigating the stability and in vitro simulation characteristics...