Case report: Cannabinoid therapy for discoid lupus erythematosus in a dog
Front Vet Sci. 2024 Feb 9;11:1309167. doi: 10.3389/fvets.2024.1309167. eCollection 2024. ABSTRACT Discoid lupus erythematosus (DLE) is a common autoimmune skin disease in dogs. Conventional treatments,...
Association between CNR1 gene polymorphisms and susceptibility to diabetic nephropathy in Iraqi patients with T2DM
J Med Life. 2023 Nov;16(11):1663-1669. doi: 10.25122/jml-2023-0181. ABSTRACT In individuals with type 2 diabetes mellitus (T2DM), the cannabinoid receptor 1 (CNR1) gene polymorphism has been...
In silico analyses of the involvement of GPR55, CB1R and TRPV1: response to THC, contribution to temporal lobe epilepsy, structural modeling and updated evolution
Front Neuroinform. 2024 Feb 7;18:1294939. doi: 10.3389/fninf.2024.1294939. eCollection 2024. ABSTRACT INTRODUCTION: The endocannabinoid (eCB) system is named after the discovery that endogenous cannabinoids bind to...
Cannabidiol protects C2C12 myotubes against cisplatin-induced atrophy by regulating oxidative stress
Am J Physiol Cell Physiol. 2024 Feb 26. doi: 10.1152/ajpcell.00622.2023. Online ahead of print. ABSTRACT Cancer and chemotherapy can both cause cachexia, a complex multi-organ...
Enhancement of the biological activity of hydroxytyrosol through its oxidation by laccase from Trametes versicolor
J Biotechnol. 2024 Feb 23:S0168-1656(24)00052-X. doi: 10.1016/j.jbiotec.2024.02.011. Online ahead of print. ABSTRACT The laccase-catalyzed oxidation of hydroxytyrosol (HT) towards the formation of its bioactive oligomer...
Engineering cannabinoid production in Saccharomyces cerevisiae
Biotechnol J. 2024 Feb;19(2):e2300507. doi: 10.1002/biot.202300507. ABSTRACT Phytocannabinoids are natural products with highly interesting pharmacological properties mainly produced by plants. The production of cannabinoids in...
Engineering cannabinoid production in Saccharomyces cerevisiae
Biotechnol J. 2024 Feb;19(2):e2300507. doi: 10.1002/biot.202300507. ABSTRACT Phytocannabinoids are natural products with highly interesting pharmacological properties mainly produced by plants. The production of cannabinoids in...
Engineering cannabinoid production in Saccharomyces cerevisiae
Biotechnol J. 2024 Feb;19(2):e2300507. doi: 10.1002/biot.202300507. ABSTRACT Phytocannabinoids are natural products with highly interesting pharmacological properties mainly produced by plants. The production of cannabinoids in...
Elderberry diet enhances motor performance and reduces neuroinflammation-induced cell death in cerebellar ataxia rat models
J Chem Neuroanat. 2024 Feb 22:102399. doi: 10.1016/j.jchemneu.2024.102399. Online ahead of print. ABSTRACT Cerebellar ataxia (CA) is a condition in which cerebellar dysfunction results in...
Sambucus williamsii Hance: A comprehensive review of traditional uses, processing specifications, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics
J Ethnopharmacol. 2024 Feb 22:117940. doi: 10.1016/j.jep.2024.117940. Online ahead of print. ABSTRACT OBJECTIVE: Sambucus williamsii Hance, belonging to the Sambucus L. family (Viburnaceae), possesses medicinal...
Development of the BioBattery: A novel enzyme fuel cell using a multicopper oxidase as an anodic enzyme
Biosens Bioelectron. 2024 Feb 8;252:116092. doi: 10.1016/j.bios.2024.116092. Online ahead of print. ABSTRACT This work presents the development of an enzyme fuel cell, termed “BioBattery”, that...
Targeting the endocannabinoid system for the management of low back pain
Curr Opin Pharmacol. 2024 Feb 23;75:102438. doi: 10.1016/j.coph.2024.102438. Online ahead of print. ABSTRACT Low back pain (LBP) is a major unmet clinical need. The endocannabinoid...
Investigation of neuroprotective and therapeutic effects of cannabidiol in an acute coronary syndrome model
Neurosci Lett. 2024 Feb 22:137689. doi: 10.1016/j.neulet.2024.137689. Online ahead of print. ABSTRACT PURPOSE: The ischemia-reperfusion (I/R) injury seen in the heart can cause severe damage...
Repeated cannabidiol treatment affects neuroplasticity and endocannabinoid signaling in the prefrontal cortex of the Flinders Sensitive Line (FSL) rat model of depression
Neuropharmacology. 2024 Feb 22:109870. doi: 10.1016/j.neuropharm.2024.109870. Online ahead of print. ABSTRACT Delayed therapeutic responses and limited efficacy are the main challenges of existing antidepressant drugs,...
T-DOpE probes reveal sensitivity of hippocampal oscillations to cannabinoids in behaving mice
Nat Commun. 2024 Feb 24;15(1):1686. doi: 10.1038/s41467-024-46021-4. ABSTRACT Understanding the neural basis of behavior requires monitoring and manipulating combinations of physiological elements and their interactions...