Vascular endothelium: functioning in norm, changes in atherosclerosis and current dietary approaches to improve endothelial function
Mini Rev Med Chem. 2015;15(4):338-50. doi: 10.2174/1389557515666150226114031. ABSTRACT The endothelium represents not only a simple cellular monolayer that lines the vascular tree in humans and...
Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study
J Agric Food Chem. 2016 Apr 27;64(16):3186-95. doi: 10.1021/acs.jafc.6b00624. Epub 2016 Apr 18. ABSTRACT In this study, the mechanisms by which pu-erh tea extract (PETE)...
Estrogens and Coronary Artery Disease: New Clinical Perspectives
Adv Pharmacol. 2016;77:307-60. doi: 10.1016/bs.apha.2016.05.003. Epub 2016 Jun 29. ABSTRACT In premenopausal women, endogenous estrogens are associated with reduced prevalence of arterial hypertension, coronary artery...
Natural Products with Antiplatelet Action
Curr Pharm Des. 2017;23(8):1228-1246. doi: 10.2174/1381612823666161123151611. ABSTRACT BACKGROUND: Complex hemostatic mechanisms are involved in the pathophysiology of various diseases, including cardiovascular diseases. Among them, dysregulation...
Protective Effect of Epigallocatechin Gallate on Endothelial Disorders in Atherosclerosis
J Cardiovasc Pharmacol. 2020 Apr;75(4):292-298. doi: 10.1097/FJC.0000000000000792. ABSTRACT Healthy vascular endothelial cells regulate vascular tone and permeability, prevent vessel wall inflammation, enhance thromboresistance, and contribute...
An update on vinpocetine: New discoveries and clinical implications
Eur J Pharmacol. 2018 Jan 15;819:30-34. doi: 10.1016/j.ejphar.2017.11.041. Epub 2017 Nov 26. ABSTRACT Vinpocetine, a derivative of the alkaloid vincamine, has been clinically used in...
Prolonged exposure to 1,25(OH)2D3 and high ionized calcium induces FGF-23 production in intestinal epithelium-like Caco-2 monolayer: A local negative feedback for preventing excessive calcium transport
Arch Biochem Biophys. 2018 Feb 15;640:10-16. doi: 10.1016/j.abb.2017.12.022. Epub 2018 Jan 6. ABSTRACT Overdose of oral calcium supplement and excessive intestinal calcium absorption can contribute...
Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats
Clin Exp Hypertens. 2019;41(8):708-716. doi: 10.1080/10641963.2018.1545846. Epub 2018 Nov 26. ABSTRACT Objective: Vascular dementia is the second leading cause of dementia, which is strongly associated...
Angiopoietin-1 and alphanubeta3 integrin peptide promote the therapeutic effects of L-serine in an amyotrophic lateral sclerosis/Parkinsonism dementia complex model
Aging (Albany NY). 2018 Nov 25;10(11):3507-3527. doi: 10.18632/aging.101661. ABSTRACT Amyotrophic lateral sclerosis (ALS) is an adult disorder of neurodegeneration that manifests as the destruction of...
Self-Reported Omega-3 Supplement Use Moderates the Association between Age and Exercising Cerebral Blood Flow Velocity in Older Adults
Nutrients. 2020 Mar 5;12(3):697. doi: 10.3390/nu12030697. ABSTRACT Cerebral blood flow (CBF) decreases across the lifespan, and chronic conditions such as dementia and stroke accelerate this...
ACR Appropriateness Criteria Dementia
J Am Coll Radiol. 2020 May;17(5S):S100-S112. doi: 10.1016/j.jacr.2020.01.040. ABSTRACT Degenerative disease of the central nervous system is a growing public health concern. The primary role...
Relationship between brain-derived neurotrophic factor and immune function during dietary supplement treatment of elderly with Alzheimer’s dementia
J Clin Transl Res. 2020 Jan 29;5(2):68-75. eCollection 2020 Jan 29. ABSTRACT BACKGROUND AND AIM: The objective of the present study was to investigate the...
Aster ageratoides Turcz. extract attenuates Alzheimer’s disease-associated cognitive deficits and vascular dementia-associated neuronal death
Anat Cell Biol. 2020 Jun 30;53(2):216-227. doi: 10.5115/acb.20.011. ABSTRACT Dementia is the common neurodegenerative disorder affecting the elderly, with a progressive cognitive decline and memory...
Safety of water extract of Cistanche tubulosa stems as a Novel food pursuant to Regulation (EU) 2015/2283
EFSA J. 2021 Jan 15;19(1):e06346. doi: 10.2903/j.efsa.2021.6346. eCollection 2021 Jan. ABSTRACT Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods...
Contrasting Metabolic Insufficiency in Aging and Dementia
Aging Dis. 2021 Jul 1;12(4):1081-1096. doi: 10.14336/AD.2021.0104. eCollection 2021 Jul. ABSTRACT Metabolic insufficiency and neuronal dysfunction occur in normal aging but is exaggerated in dementia...