UPLC-ESI-MS/MS profiling and hepatoprotective activities of Stevia leaves extract, butanol fraction and stevioside against radiation-induced toxicity in rats
Nat Prod Res. 2021 Dec 13:1-7. doi: 10.1080/14786419.2021.2015594. Online ahead of print. ABSTRACT Stevioside is the major component of Stevia rebaudiana (Bertoni) leaves, family Asteraceae....
Green extraction and characterization of leaves phenolic compounds: a comprehensive review
Crit Rev Food Sci Nutr. 2021 Dec 14:1-39. doi: 10.1080/10408398.2021.2013771. Online ahead of print. ABSTRACT Although containing significant levels of phenolic compounds (PCs), leaves biomass...
Isolation of phytochemical constituents from Stevia rebaudiana (Bert.) and evaluation of their anticancer, antimicrobial and antioxidant properties via in vitro and in silico approaches
Heliyon. 2021 Nov 26;7(12):e08475. doi: 10.1016/j.heliyon.2021.e08475. eCollection 2021 Dec. ABSTRACT The current study was designed to isolate and characterize some bioactive secondary metabolites by using...
Inhibitory effect of stevioside on calcium influx to produce antihypertension
Planta Med. 2001 Dec;67(9):796-9. doi: 10.1055/s-2001-18841. ABSTRACT Stevioside is a sweet-tasting glycoside occurring abundantly in the leaves of Stevia rebaudiana (Compositae). It has been used...
Isosteviol acts on potassium channels to relax isolated aortic strips of Wistar rat
Life Sci. 2004 Mar 26;74(19):2379-87. doi: 10.1016/j.lfs.2003.09.065. ABSTRACT Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly used as a...
Implications of oxidative stress and inflammatory process in the cytotoxicity of capsaicin in human endothelial cells: lack of DNA strand breakage
Toxicology. 2000 May 19;147(1):41-9. doi: 10.1016/s0300-483x(00)00184-0. ABSTRACT Capsaicin, a natural product of Capsicum species is known to induce excitation of nociceptive terminals involved in pain...
Frequent consumption of milk, yogurt, cold breakfast cereals, peppers, and cruciferous vegetables and intakes of dietary folate and riboflavin but not vitamins B-12 and B-6 are inversely associated with serum total homocysteine concentrations in the US population
Am J Clin Nutr. 2004 Dec;80(6):1500-7. doi: 10.1093/ajcn/80.6.1500. ABSTRACT BACKGROUND: Elevated circulating total homocysteine (tHcy) is an independent risk factor for vascular diseases. OBJECTIVE: We...
The effect of 4-week chilli supplementation on metabolic and arterial function in humans
Eur J Clin Nutr. 2007 Mar;61(3):326-33. doi: 10.1038/sj.ejcn.1602517. Epub 2006 Aug 23. ABSTRACT OBJECTIVE: To investigate the effects of regular chilli ingestion on some indicators...
Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation
J Pharm Pharmacol. 2008 Apr;60(4):473-8. doi: 10.1211/jpp.60.4.0010. ABSTRACT Inflammation is a pivotal component of a variety of diseases, such as atherosclerosis and tumour progression. Various...
Mechanisms underlying the hypertensive response induced by capsaicin
Int J Cardiol. 2010 Nov 19;145(2):358-359. doi: 10.1016/j.ijcard.2010.02.034. Epub 2010 Mar 11. ABSTRACT Acute ingestion of large quantity of chili peppers (rich source of capsaicin)...
Dermal factors influencing measurement of skin autofluorescence
Diabetes Technol Ther. 2011 Feb;13(2):165-70. doi: 10.1089/dia.2010.0123. ABSTRACT BACKGROUND: Skin autofluorescence (SAF) is a noninvasive marker of accumulation of advanced glycation end products. It predicts...
Capsaicinoids lower plasma cholesterol and improve endothelial function in hamsters
Eur J Nutr. 2013 Feb;52(1):379-88. doi: 10.1007/s00394-012-0344-2. Epub 2012 Mar 31. ABSTRACT PURPOSE: Capsaicinoids are the active compounds in chili pepper. The present study investigated...
Palatability of tastes is associated with facial circulatory responses
Chem Senses. 2014 Mar;39(3):243-8. doi: 10.1093/chemse/bjt074. Epub 2014 Jan 5. ABSTRACT To examine whether various types of taste stimuli in the oral cavity elicit unique...
Capsaicinoids but not their analogue capsinoids lower plasma cholesterol and possess beneficial vascular activity
J Agric Food Chem. 2014 Aug 20;62(33):8415-20. doi: 10.1021/jf502888h. Epub 2014 Aug 11. ABSTRACT Capsaicinoids exist in chili peppers, whereas capsinoids are present in some...
The metabolic effects of a commercially available chicken peri-peri (African bird’s eye chilli) meal in overweight individuals
Br J Nutr. 2017 Mar;117(5):635-644. doi: 10.1017/S0007114515003104. Epub 2015 Sep 11. ABSTRACT A growing body of evidence suggests that capsaicin ingestion may lead to desirable...