Thermodynamic Analysis to Evaluate the Effect of Diet on Brain Glucose Metabolism: The Case of Fish Oil
Nutrients. 2024 Feb 24;16(5):631. doi: 10.3390/nu16050631. ABSTRACT Inefficient glucose metabolism and decreased ATP production in the brain are linked to ageing, cognitive decline, and neurodegenerative...
Effect of Dietary Supplementation with Omega-3 Fatty Acid on the Generation of Regulatory T Lymphocytes and on Antioxidant Parameters and Markers of Oxidative Stress in the Liver Tissue of IL-10 Knockout Mice
Nutrients. 2024 Feb 24;16(5):634. doi: 10.3390/nu16050634. ABSTRACT INTRODUCTION: chronic low-grade inflammation, or inflammaging, emerges as a crucial element in the aging process and is associated...
The Maternal Omega-3 Long-Chain Polyunsaturated Fatty Acid Concentration in Early Pregnancy and Infant Neurodevelopment: The ECLIPSES Study
Nutrients. 2024 Feb 28;16(5):687. doi: 10.3390/nu16050687. ABSTRACT Omega-3 Long-Chain Polyunsaturated Fatty Acids (n-3 LCPUFAs) play a key role in early neurodevelopment, but evidence from observational...
Developmental and Nutritional Changes in Children with Severe Acute Malnutrition Provided with n-3 Fatty Acids Improved Ready-to-Use Therapeutic Food and Psychosocial Support: A Pilot Study in Tanzania
Nutrients. 2024 Feb 28;16(5):692. doi: 10.3390/nu16050692. ABSTRACT Children with severe acute malnutrition (SAM) are at high risk of impaired development. Contributing causes include the inadequate...
Effect of Lifelong Exposure to Dietary Plant and Marine Sources of n-3 Polyunsaturated Fatty Acids on Morphologic and Gene Expression Biomarkers of Intestinal Health in Early Life
Nutrients. 2024 Mar 1;16(5):719. doi: 10.3390/nu16050719. ABSTRACT Altered intestinal health is also associated with the incidence and severity of many chronic inflammatory conditions, which could...
UHPLC-qTOF-MS-Based Nontargeted Metabolomics to Characterize the Effects of Capsaicin on Plasma and Skin Metabolic Profiles of C57BL/6 Mice-An In vivo Experimental Study
Drug Des Devel Ther. 2024 Mar 5;18:719-729. doi: 10.2147/DDDT.S423974. eCollection 2024. ABSTRACT BACKGROUND: Capsaicin is the main compound found in chili pepper and has complex...
Use of sawdust for production of ligninolytic enzymes by white-rot fungi and pharmaceutical removal
Bioprocess Biosyst Eng. 2024 Mar 14. doi: 10.1007/s00449-024-02976-8. Online ahead of print. ABSTRACT Use of white-rot fungi for enzyme-based bioremediation of wastewater is of high...
Reduced Subjective Cognitive Concerns With Neurobehavioral Therapy in Functional Seizures and Traumatic Brain Injury
J Neuropsychiatry Clin Neurosci. 2024 Mar 14:appineuropsych20230138. doi: 10.1176/appi.neuropsych.20230138. Online ahead of print. ABSTRACT OBJECTIVE: Functional seizures are common among people with traumatic brain injury...
Advances in understanding migraine pathophysiology: a bench to bedside review of research insights and therapeutics
Front Mol Neurosci. 2024 Feb 28;17:1355281. doi: 10.3389/fnmol.2024.1355281. eCollection 2024. ABSTRACT The individual and global burden of migraine is of such significance that there are...
Linderane Attenuates Complete Freund’s Adjuvant-Induced Pain and Anxiety in Mice by Restoring Anterior Cingulate Cortex Microglia M2 Polarization through Activating Cannabinoid 2 Receptor
ACS Pharmacol Transl Sci. 2024 Feb 15;7(3):797-808. doi: 10.1021/acsptsci.3c00321. eCollection 2024 Mar 8. ABSTRACT Chronic pain is a common condition that causes negative emotions as...
Deformable Vesicles with Edge Activators for the Transdermal Delivery of Non-Psychoactive Cannabinoids
Curr Pharm Des. 2024 Mar 12. doi: 10.2174/0113816128289593240226071813. Online ahead of print. ABSTRACT BACKGROUND: Transdermal delivery of highly lipophilic molecules is challenging due to the...
An iPSC line (FINi003-A) from a male with late-onset developmental and epileptic encephalopathy caused by a heterozygous p.E1211K variant in the SCN2A gene encoding the voltage-gated sodium channel Nav1.2
Stem Cell Res. 2024 Feb 28;76:103367. doi: 10.1016/j.scr.2024.103367. Online ahead of print. ABSTRACT Many developmental and epileptic encephalopathies (DEEs) result from variants in cation channel...
ERRγ-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress
Redox Biol. 2024 Mar 5;71:103107. doi: 10.1016/j.redox.2024.103107. Online ahead of print. ABSTRACT Fibroblast growth factor 23 (FGF23) is a member of endocrine FGF family, along...
Therapeutic applicability of cannabidiol and other phytocannabinoids in epilepsy, multiple sclerosis and Parkinson’s disease and in comorbidity with psychiatric disorders
Basic Clin Pharmacol Toxicol. 2024 Mar 13. doi: 10.1111/bcpt.13997. Online ahead of print. ABSTRACT Studies have demonstrated the neuroprotective effect of cannabidiol (CBD) and other...
Medical cannabis use in oncology and associated outcomes: A scoping review
J Oncol Pharm Pract. 2024 Mar 13:10781552241239006. doi: 10.1177/10781552241239006. Online ahead of print. ABSTRACT BACKGROUND: Natural and synthetic cannabinoids are being used worldwide to treat...