Modulatory Effects of Biosynthesized Gold Nanoparticles Conjugated with Curcumin and Paclitaxel on Tumorigenesis and Metastatic Pathways-In Vitro and In Vivo Studies
Int J Mol Sci. 2022 Feb 15;23(4):2150. doi: 10.3390/ijms23042150. ABSTRACT BACKGROUND: Breast cancer is the most common cancer in women globally, and diagnosing it early...
Enhancement of anti-PD-1/PD-L1 immunotherapy for osteosarcoma using an intelligent autophagy-controlling metal organic framework
Biomaterials. 2022 Feb 17;282:121407. doi: 10.1016/j.biomaterials.2022.121407. Online ahead of print. ABSTRACT Poor immunogenicity and compromised T cell infiltration impede the application of immune-checkpoint blockade (ICB)...
Angiogenesis as Therapeutic Target in Metastatic Prostate Cancer – Narrowing the Gap Between Bench and Bedside
Front Immunol. 2022 Feb 10;13:842038. doi: 10.3389/fimmu.2022.842038. eCollection 2022. ABSTRACT Angiogenesis in metastatic castration-resistant prostate cancer (mCRPC) has been extensively investigated as a promising druggable...
Characterization of the L-Arginine/Nitric Oxide Pathway and Oxidative Stress in Pediatric Patients with Atopic Diseases
Int J Mol Sci. 2022 Feb 15;23(4):2136. doi: 10.3390/ijms23042136. ABSTRACT INTRODUCTION: L-Arginine (Arg) is a semi-essential amino acid. Constitutive and inducible nitric oxide synthase (NOS)...
Curcumin alleviates lipopolysaccharides-induced inflammation and apoptosis in vascular smooth muscle cells via inhibition of the NF-kappaB and JNK signaling pathways
Inflammopharmacology. 2022 Mar 1. doi: 10.1007/s10787-021-00912-w. Online ahead of print. ABSTRACT Curcumin plays an important role in inflammation regulation. This study aimed to investigate the...
Potentiality of curcumin on ISHAK scoring system and the expressions of BAX, IL-17A, and EGF in the treatment ofSchistosoma mansoni infection using Swiss albino mice
Trop Biomed. 2022 Mar 1;39(1):36-46. doi: 10.47665/tb.39.1.001. ABSTRACT The present study evaluated the antiparasitic effect of curcumin extract on Schistosoma mansoni in Swiss albino mice....
Characterization and in vitro release of inhalation quercetin solid lipid microparticles: Effect of lipid
J Adv Pharm Technol Res. 2022 Jan-Mar;13(1):11-17. doi: 10.4103/japtr.japtr_263_21. Epub 2022 Jan 21. ABSTRACT This study purposes to develop solid lipid microparticles (SLM) inhalation delivery...
Characterization of virulence factors and antibacterial activity of curcumin in hypervirulent Klebsiella pneumoniae
Future Microbiol. 2022 Mar 24. doi: 10.2217/fmb-2021-0222. Online ahead of print. ABSTRACT Aim: Klebsiella pneumoniae is a threat to human health due to its carbapenem-resistance...
Molecular docking studies of natural immunomodulators indicate their interactions with the CD40L of CD40/CD40L pathway and CSF1R kinase domain of microglia
J Mol Model. 2022 Mar 24;28(4):101. doi: 10.1007/s00894-022-05084-0. ABSTRACT Natural products have proved beneficial in reducing neuroinflammation in neurological diseases. Their impacts have also been...
Chemical composition and antioxidant activity of extracts from Moroccan fresh fava beans pods (Vicia Faba L.)
Rocz Panstw Zakl Hig. 2022;73(1):79-86. doi: 10.32394/rpzh.2022.0194. ABSTRACT BACKGROUND: In Morocco, fava beans are widely used as a main meal or as an ingredient in...
Dietary curcumin nanoparticles promoted the performance, antioxidant activity, and humoral immunity, and modulated the hepatic and intestinal histology of Nile tilapia fingerlings
Fish Physiol Biochem. 2022 Apr 5. doi: 10.1007/s10695-022-01066-4. Online ahead of print. ABSTRACT The current study investigated the effects of dietary curcumin nanoparticles (C-NPs) on...
Quercetin May Improve Fat Graft Survival by Promoting Fat Browning Peripherally
Aesthetic Plast Surg. 2022 Mar 24. doi: 10.1007/s00266-022-02857-z. Online ahead of print. ABSTRACT BACKGROUND: Adipose browning occurs after white fat transfer. But its location and...
Effects of ginger (Zingiber officinale) on gingival fibroblasts: An in vitro study
Clin Exp Dent Res. 2022 Apr 5. doi: 10.1002/cre2.575. Online ahead of print. ABSTRACT OBJECTIVES: Ginger, the powdered rhizome of the herb Zingiber officinale, is...
The golden spice curcumin in cancer: A perspective on finalized clinical trials during the last 10 years
J Cancer Res Ther. 2022 Jan-Mar;18(1):19-26. doi: 10.4103/jcrt.JCRT_1017_20. ABSTRACT Curcumin, the key bioactive phytochemical present in turmeric (Curcuma longa L.), is the most studied natural...
Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing the JAK1/STAT1 pathway
Biochem Cell Biol. 2022 Apr 5. doi: 10.1139/bcb-2021-0423. Online ahead of print. ABSTRACT To date, there is no effective treatment strategy for Intracerebral hemorrhage (ICH)....