Canadians’ use of cannabis for therapeutic purposes since legalization of recreational cannabis: a cross-sectional analysis by medical authorization status
BMC Med. 2024 Apr 8;22(1):150. doi: 10.1186/s12916-024-03370-7. ABSTRACT BACKGROUND: There has been a precipitous decline in authorizations for medical cannabis since non-medical cannabis was legalized...
Trends in U.S. Medical Cannabis Registrations, Authorizing Clinicians, and Reasons for Use From 2020 to 2022
Ann Intern Med. 2024 Apr 9. doi: 10.7326/M23-2811. Online ahead of print. ABSTRACT BACKGROUND: As medical cannabis availability increases, up-to-date trends in medical cannabis licensure...
Cytotoxicity phenylpropanoid amides from the seed of Cannabis sativa L
Nat Prod Res. 2024 Apr 8:1-8. doi: 10.1080/14786419.2024.2338800. Online ahead of print. ABSTRACT Two novel phenylpropanoid amides, namely huomarenamide A (1) and huomarenamide B (2),...
A narrative review on therapeutic potential of naringenin in colorectal cancer: Focusing on molecular and biochemical processes
Cell Biochem Funct. 2024 Apr;42(3):e4011. doi: 10.1002/cbf.4011. ABSTRACT Colorectal cancer (CRC) is a common and highly metastatic cancer affecting people worldwide. Drug resistance and unwanted...
Perspectives regarding cannabis use: Results from a qualitative study of individuals engaged in substance use treatment in Georgia and Connecticut
Drug Alcohol Depend Rep. 2024 Mar 24;11:100228. doi: 10.1016/j.dadr.2024.100228. eCollection 2024 Jun. ABSTRACT OBJECTIVE: Cannabis use is increasingly pervasive throughout the U.S. People in treatment...
Pharmacokinetic of two oral doses of a 1:20 THC:CBD cannabis herbal extract in cats
Front Vet Sci. 2024 Feb 23;11:1352495. doi: 10.3389/fvets.2024.1352495. eCollection 2024. ABSTRACT OBJECTIVE: To determine the pharmacokinetics (PK) of two oral doses of a Cannabis herbal...
Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons
bioRxiv [Preprint]. 2024 Mar 29:2024.02.17.579842. doi: 10.1101/2024.02.17.579842. ABSTRACT The transcription repressor REST in the dorsal root ganglion (DRG) is upregulated by peripheral nerve injury and...
Traumatic Brain Injury Outcomes After Recreational Cannabis Use
Neuropsychiatr Dis Treat. 2024 Apr 3;20:809-821. doi: 10.2147/NDT.S453616. eCollection 2024. ABSTRACT PURPOSE: Basic science data indicate potential neuroprotective effects of cannabinoids in traumatic brain injury...
Investigating the Impact of Cannabis Consumption on Hospital Outcomes in Patients With Primary Spontaneous Pneumothorax: A Nationwide Analysis
Cureus. 2024 Mar 5;16(3):e55601. doi: 10.7759/cureus.55601. eCollection 2024 Mar. ABSTRACT Introduction Existing data suggest an association between primary spontaneous pneumothorax (PSP) and cannabis consumption, although...
Cannabidiol induces ERK activation and ROS production to promote autophagy and ferroptosis in glioblastoma cells
Chem Biol Interact. 2024 Apr 5:110995. doi: 10.1016/j.cbi.2024.110995. Online ahead of print. ABSTRACT Small molecule-driven ERK activation is known to induce autophagy and ferroptosis in...
Curcumin: An innovative approach for postharvest control of Alternaria alternata induced black rot in cherry tomatoes
Fungal Biol. 2024 Apr;128(2):1691-1697. doi: 10.1016/j.funbio.2024.02.005. Epub 2024 Feb 15. ABSTRACT Curcumin, a natural bioactive compound derived from Curcuma longa, has been widely recognized for...
Efficient activity screening of new glucuronoyl esterases using a pNP-based assay
Enzyme Microb Technol. 2024 Apr 3;178:110444. doi: 10.1016/j.enzmictec.2024.110444. Online ahead of print. ABSTRACT Glucuronoyl esterases (CE15, EC 3.1.1.117) catalyze the hydrolysis of ester bonds between...
Automated Extraction and LC-MS/MS Analysis of 11-Nor-9-carboxy-tetrahydrocannabinol Isomers and Prevalence in Authentic Urine Specimens
J Anal Toxicol. 2024 Apr 6:bkae031. doi: 10.1093/jat/bkae031. Online ahead of print. ABSTRACT 11-Nor-9-carboxy-Δ9-tetrahydrocannabinol (Δ9-THCCOOH) is the most frequently detected illicit drug metabolite in the...
Quantitation of hexahydrocannabinol (HHC) and metabolites in blood from DUID-cases
J Anal Toxicol. 2024 Apr 6:bkae030. doi: 10.1093/jat/bkae030. Online ahead of print. ABSTRACT Hexahydrocannabinol (HHC) was first reported in the EU in May 2022. HHC...
Substance use and self-poisoning in schizophrenia: 11-year findings from a national clinical survey of suicide in mental health patients in England
Schizophr Res. 2024 Apr 5;267:254-260. doi: 10.1016/j.schres.2024.03.048. Online ahead of print. ABSTRACT Suicide is the leading cause of unnatural death among people with schizophrenia. Substance...