Potential Therapeutic Targets to Modulate the Endocannabinoid System in Alzheimer’s Disease
Int J Mol Sci. 2024 Apr 5;25(7):4050. doi: 10.3390/ijms25074050. ABSTRACT Alzheimer’s disease (AD), the most common neurodegenerative disease (NDD), is characterized by chronic neuronal cell...
Marijuana use among community-dwelling older adults: A population-based study
Int J Geriatr Psychiatry. 2024 Apr;39(4):e6086. doi: 10.1002/gps.6086. ABSTRACT OBJECTIVES: There is a paucity of population-level data on marijuana use and mental health and functioning...
Hemp Seed Oil Inhibits the Adipogenicity of the Differentiation-Induced Human Mesenchymal Stem Cells through Suppressing the Cannabinoid Type 1 (CB1)
Molecules. 2024 Mar 31;29(7):1568. doi: 10.3390/molecules29071568. ABSTRACT Central and peripheral mechanisms of the endocannabinoid system (ECS) favor energy intake and storage. The ECS, especially cannabidiol...
Cannabinoids and Sleep: Exploring Biological Mechanisms and Therapeutic Potentials
Int J Mol Sci. 2024 Mar 22;25(7):3603. doi: 10.3390/ijms25073603. ABSTRACT The endogenous cannabinoid system (ECS) plays a critical role in the regulation of various physiological...
Possible Role of Cannabis in the Management of Neuroinflammation in Patients with Post-COVID Condition
Int J Mol Sci. 2024 Mar 29;25(7):3805. doi: 10.3390/ijms25073805. ABSTRACT The post-COVID condition (PCC) is a pathology stemming from COVID-19, and studying its pathophysiology, diagnosis,...
Improved Long-Term Preservation of Cannabis Inflorescence by Utilizing Integrated Pre-Harvest Hexanoic Acid Treatment and Optimal Post-Harvest Storage Conditions
Plants (Basel). 2024 Mar 30;13(7):992. doi: 10.3390/plants13070992. ABSTRACT The effort to maintain cannabinoid and terpene levels in harvested medicinal cannabis inflorescence is crucial, as many...
Preliminary Results from a Phase IV Surveillance Study of Medical Cannabis Use in Australian Patients With Advanced Cancer Receiving Palliative Care
J Palliat Med. 2024 Apr 12. doi: 10.1089/jpm.2023.0358. Online ahead of print. ABSTRACT Introduction: Our research group is conducting three large randomized placebo-controlled trials of...
Investigating the Relationship Between Cannabis Expectancies and Anxiety, Depression, and Pain Responses After Acute Flower and Edible Cannabis Use
Cannabis Cannabinoid Res. 2024 Apr 12. doi: 10.1089/can.2023.0264. Online ahead of print. ABSTRACT Objective: Cannabis has been touted for a host of pharmacological and therapeutic...
Cannabinoids for Acute Pain Management: Approaches and Rationale
Curr Pain Headache Rep. 2024 Apr 12. doi: 10.1007/s11916-024-01252-4. Online ahead of print. ABSTRACT PURPOSE OF THE REVIEW: Acute pain management remains a challenge and...
Knockdown siRNA Targeting GPR55 Reveals Significant Differences Between the Anti-inflammatory Actions of KLS-13019 and Cannabidiol
J Mol Neurosci. 2024 Apr 11;74(2):41. doi: 10.1007/s12031-024-02217-3. ABSTRACT KLS-13019 was reported previously to reverse paclitaxel-induced mechanical allodynia in a mouse model of chemotherapy-induced peripheral...
Reactions to vaping cessation messaging and strategies among US young adults who use e-cigarettes
Tob Prev Cessat. 2024 Apr 11;10. doi: 10.18332/tpc/186271. eCollection 2024. ABSTRACT INTRODUCTION: Despite high rates of young adult e-cigarette use, research informing cessation interventions for...
Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases – a systematic review
Z Gastroenterol. 2024 Apr 11. doi: 10.1055/a-2279-5045. Online ahead of print. ABSTRACT Phytotherapeutics are gaining influence in the treatment of gastroenterological diseases. Their popularity and...
GPCR kinase subtype requirements for arrestin-2 and -3 translocation to the type-1 cannabinoid receptor and the consequences on G protein signalling
Biochem Pharmacol. 2024 Apr 9:116190. doi: 10.1016/j.bcp.2024.116190. Online ahead of print. ABSTRACT Arrestins are key negative regulators of G Protein-Coupled Receptors (GPCRs) through mediation of...
Characteristics of women concordant and discordant for urine drug screens for cannabis exposure and self-reported cannabis use during pregnancy
Neurotoxicol Teratol. 2024 Apr 9:107351. doi: 10.1016/j.ntt.2024.107351. Online ahead of print. ABSTRACT BACKGROUND: Increasing cannabis use among pregnant people and equivocal evidence linking prenatal cannabis...
Reduced fetal cerebral blood flow predicts perinatal mortality in a mouse model of prenatal alcohol and cannabinoid exposure
BMC Pregnancy Childbirth. 2024 Apr 11;24(1):263. doi: 10.1186/s12884-024-06436-9. ABSTRACT BACKGROUND: Children exposed prenatally to alcohol or cannabinoids individually can exhibit growth deficits and increased risk...