Autophagy Activation Promoted by Pulses of Light and Phytochemicals Counteracting Oxidative Stress during Age-Related Macular Degeneration
Antioxidants (Basel). 2023 May 30;12(6):1183. doi: 10.3390/antiox12061183. ABSTRACT The seminal role of autophagy during age-related macular degeneration (AMD) lies in the clearance of a number...
Fungal Biotransformation of Hazardous Organic Compounds in Wood Waste
Molecules. 2023 Jun 17;28(12):4823. doi: 10.3390/molecules28124823. ABSTRACT A diverse spectrum of organisms, such as fungi, bacteria, and actinomycetes, can degrade and transform organic matter, including...
Characterization, In Vitro Biological Activity and In Vivo Cardioprotective Properties of Trametes versicolor (L.:Fr.) Quél. Heteropolysaccharides in a Rat Model of Metabolic Syndrome
Pharmaceuticals (Basel). 2023 May 25;16(6):787. doi: 10.3390/ph16060787. ABSTRACT The present study aimed to examine the biological activity and cardioprotective potential of Trametes versicolor heteropolysaccharides (TVH)...
Lignin Nanoparticles with Entrapped Thymus spp. Essential Oils for the Control of Wood-Rot Fungi
Polymers (Basel). 2023 Jun 17;15(12):2713. doi: 10.3390/polym15122713. ABSTRACT After decades of utilization of fossil-based and environmentally hazardous compounds for wood preservation against fungal attack, there...
Functional Expression of IP, 5-HT4, D1, A2A, and VIP Receptors in Human Odontoblast Cell Line
Biomolecules. 2023 May 23;13(6):879. doi: 10.3390/biom13060879. ABSTRACT Odontoblasts are involved in sensory generation as sensory receptor cells and in dentin formation. We previously reported that...
Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity
Biomolecules. 2023 May 25;13(6):887. doi: 10.3390/biom13060887. ABSTRACT Pannexin-1 (Panx1) hemichannel is a non-selective transmembrane channel that may play important roles in intercellular signaling by allowing...
The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition
Biomedicines. 2023 May 26;11(6):1546. doi: 10.3390/biomedicines11061546. ABSTRACT Neuropathic pain is a chronic disabling condition with a 7-10% of prevalence in the general population that is...
Cannabis for the Treatment of Fibromyalgia: A Systematic Review
Biomedicines. 2023 Jun 2;11(6):1621. doi: 10.3390/biomedicines11061621. ABSTRACT Fibromyalgia is a common disease syndrome characterized by chronic pain and fatigue in conjunction with cognitive dysfunction such...
Exploring the Therapeutic Potential of Cannabinoid Receptor Antagonists in Inflammation, Diabetes Mellitus, and Obesity
Biomedicines. 2023 Jun 8;11(6):1667. doi: 10.3390/biomedicines11061667. ABSTRACT Recently, research has greatly expanded the knowledge of the endocannabinoid system (ECS) and its involvement in several therapeutic...
Hydrogen Sulfide Interacting with Cannabinoid 2 Receptors during Sciatic Nerve Injury-Induced Neuropathic Pain
Antioxidants (Basel). 2023 May 30;12(6):1179. doi: 10.3390/antiox12061179. ABSTRACT Hydrogen sulfide (H2S) donors make opioids more effective in inhibiting nociception during inflammatory and neuropathic pain. We...
The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer’s Disease in AppNL-G-F Knock-In Mice
Biology (Basel). 2023 May 31;12(6):805. doi: 10.3390/biology12060805. ABSTRACT BACKGROUND: The endocannabinoid system (ECS) and associated lipid transmitter-based signaling systems play an important role in modulating...
Genetic Insights into the Molecular Pathophysiology of Depression in Parkinson’s Disease
Medicina (Kaunas). 2023 Jun 13;59(6):1138. doi: 10.3390/medicina59061138. ABSTRACT Background and Objectives: Parkinson’s disease (PD) is a clinically heterogeneous disorder with poorly understood pathological contributing factors....
The Effect of Mineral Fertilization on the Content of Bioactive Compounds in Hemp Seeds and Oil
Molecules. 2023 Jun 20;28(12):4870. doi: 10.3390/molecules28124870. ABSTRACT The popularity of hemp cultivation for industrial purposes has been steadily growing for many years. With the addition...
THC-Reduced Cannabis sativa L.-How Does the Solvent Determine the Bioavailability of Cannabinoids Given Orally?
Nutrients. 2023 Jun 6;15(12):2646. doi: 10.3390/nu15122646. ABSTRACT The bioavailability levels of cannabidiol (CBD) and tetrahydrocannabinol (THC) determine their pharmacological effects. Therefore, for medical purposes, it...
New Pieces for an Old Puzzle: Approaching Parkinson’s Disease from Translatable Animal Models, Gut Microbiota Modulation, and Lipidomics
Nutrients. 2023 Jun 16;15(12):2775. doi: 10.3390/nu15122775. ABSTRACT Parkinson’s disease (PD) is a severe neurodegenerative disease characterized by disabling motor alterations that are diagnosed at a...