Pre-puberty cannabichromene exposure modulates reproductive function via alteration of spermatogenesis, steroidogenesis, and eNOS pathway metabolites
Toxicol Rep. 2023 Jun 3;10:690-705. doi: 10.1016/j.toxrep.2023.06.001. eCollection 2023. ABSTRACT BACKGROUND: Cannabis and cannabinoids affect almost every system of the body and exert systemic effects...
Cannabis: a multifaceted plant with endless potentials
Front Pharmacol. 2023 Jun 15;14:1200269. doi: 10.3389/fphar.2023.1200269. eCollection 2023. ABSTRACT Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses...
A subtle structural modification of a synthetic cannabinoid receptor agonist drastically increases its efficacy at the CB1 receptor
bioRxiv. 2023 Jun 12:2023.06.10.544442. doi: 10.1101/2023.06.10.544442. Preprint. ABSTRACT The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances has posed considerable public health...
A transdiagnostic approach to negative symptoms: exploring factor structure and negative symptoms in bipolar disorders
Front Psychiatry. 2023 Jun 16;14:1136097. doi: 10.3389/fpsyt.2023.1136097. eCollection 2023. ABSTRACT BACKGROUND: Negative symptoms are increasingly recognized as transdiagnostic phenomena, linked to reduced quality of life...
Addressing the Smoking-Hypertension Paradox in Pregnancy: Insight from a Multiethnic US Birth Cohort
Precis Nutr. 2023 Jun;2(2):e00035. Epub 2023 May 24. ABSTRACT BACKGROUND: Smoking during pregnancy has been associated with reduced risk of a spectrum of hypertensive (HTN)...
Cannabidiol and cannabis-inspired terpene blends have acute prosocial effects in the BTBR mouse model of autism spectrum disorder
Front Neurosci. 2023 Jun 16;17:1185737. doi: 10.3389/fnins.2023.1185737. eCollection 2023. ABSTRACT INTRODUCTION: Cannabidiol (CBD) is a non-intoxicating phytocannabinoid with increasing popularity due to its purported therapeutic...
A subtle structural modification of a synthetic cannabinoid receptor agonist drastically increases its efficacy at the CB1 receptor
bioRxiv. 2023 Jun 12:2023.06.10.544442. doi: 10.1101/2023.06.10.544442. Preprint. ABSTRACT The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances has posed considerable public health...
Oxylipin secretion by human CD3+ T lymphocytes in vitro is modified by the exogenous essential fatty acid ratio and life stage
Front Immunol. 2023 Jun 14;14:1206733. doi: 10.3389/fimmu.2023.1206733. eCollection 2023. ABSTRACT Immune function changes across the life stages; for example, senior adults exhibit a tendency towards...
Cytokine storm associated with severe COVID-19 infections: The potential mitigating role of omega-3 fatty acid triglycerides in the ICU
FASEB J. 2023 Aug;37(8):e23066. doi: 10.1096/fj.202300396R. ABSTRACT Cytokine storm during severe COVID-19 infection increases the risk of mortality in critically ill patients in the intensive...
Ruminal responses, digestibility, and blood parameters of beef cattle fed diets with different oilseeds
Trop Anim Health Prod. 2023 Jul 1;55(4):254. doi: 10.1007/s11250-023-03682-5. ABSTRACT It aimed to evaluate the effects of different whole oilseeds in lipid-rich diets on nutrient...
Protective effect of intervention with cannabinoid type-2 receptor agonist JWH133 on pulmonary fibrosis in mice
Zhonghua Nei Ke Za Zhi. 2023 Jul 1;62(7):841-849. doi: 10.3760/cma.j.cn112138-20220907-00663. ABSTRACT Objective: JWH133, a cannabinoid type 2 receptor agonist, was tested for its ability to...
Organophosphate agent action at the fatty acid amide hydrolase enhancing anandamide-induced apoptosis in NG108-15 cells
J Toxicol Sci. 2023;48(7):421-428. doi: 10.2131/jts.48.421. ABSTRACT Organophosphate (OP) agents are continuously utilized in large amount throughout the globe for crop protection and public health,...
Cannabinoid mechanisms contribute to the therapeutic efficacy of the kratom alkaloid mitragynine against neuropathic, but not inflammatory pain
Life Sci. 2023 Jun 29:121878. doi: 10.1016/j.lfs.2023.121878. Online ahead of print. ABSTRACT AIMS: Mitragynine (MG) is an alkaloid found in Mitragyna speciosa (kratom), a plant...
Peroxisome proliferator-activated receptor gamma (PPARγ) activation: a potential treatment for ascites syndrome in broiler chickens
Poult Sci. 2023 Jun 9;102(9):102859. doi: 10.1016/j.psj.2023.102859. Online ahead of print. ABSTRACT Ascites (serous fluid accumulation in the abdominal cavity) has been observed worldwide in...
A novel aspect on different preservation methods for tomato paste by examining the protective effect of herb and spice oils
Food Chem. 2023 Jun 25;427:136715. doi: 10.1016/j.foodchem.2023.136715. Online ahead of print. ABSTRACT In this study, the effect of essential oils of herbs and spices on...